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Phenotype phenotyping

Gene Promoter/Receptor (Fold overexpression) Phenotype Phenotype... [Pg.299]

Phenotype Phenotype is an observable characteristic displayed by an organism. These characteristics can be controlled by genes, by the environment, or by a combination of both. The characteristic can be directly observable, such as having brown eyes. In some cases, the phenotype will be measurable, such as having high blood pressure. [Pg.211]

PEO (progressive external ophthalmoplegia) 302, 525 Pericardial effusion 414 Perioral cutaneous eruption 197 Peripheral nervous system (PNS) 118 Peritonitis 641 Pes equinovarus 95 Phenotype / phenotypic... [Pg.697]

Plasmid DNAs. Plasmids are nucleic acid molecules capable of intracellular extrachromosomal repHcation. Usually plasmids are circular DNA species, but linear and RNA plasmids are known. In nature, plasmids can assume a variety of lifestyles. Plasmids can recombine into the host chromosome, be packaged into vims particles, and repHcate at high or low copy number relative to the host chromosome. Additionally, their information can affect the host phenotype. Whereas no single plasmid is usually capable of all these behaviors, the properties of various plasmids have been used to constmct vectors for a variety of purposes. [Pg.229]

Mutagenic PGR. More recently, methods have been developed to use the PGR reaction to randomly mutagenize a defined sequence (25). The Taq polymerase used in PGR misincorporates nucleotides in a random fashion if manganese dichloride [7773-01 -5] MnGl2, is included in the reaction buffer during PGR. The Hbrary of mutagenized PGR products can be screened for the desired phenotype. [Pg.237]

About 30% of the patients on chronic procainamide dosing develop a systemic lupusfike syndrome consisting of arthralgia, myalgia, skin rash, and fever. Patients who are slow acetylator phenotypes may be prone to this condition. Some may exhibit pleuropneumonic involvement and hepatomegaly... [Pg.113]

Testosterone, the principal male sex steroid hormone, is synthesized in five steps from cholesterol, as shown below. In the last step, five isozymes catalyze the 17/3-hydroxysteroid dehydrogenase reactions that interconvert 4-androstenedione and testosterone. Defects in the synthesis or action of testosterone can impair the development of the male phenotype during embryogenesis and cause the disorders of human sexuality termed male pseudohermaphroditism. Specifically, mutations in isozyme 3 of the 17/3-hydroxysteroid dehydrogenase in the fetal testis impair the for-... [Pg.257]

Vanhanen, H. X, Blomqvist, S., Ehnholm, C., et al., 1993. Sernm cholesterol, cholesterol precursors, and plant sterols in hypercholesterolemic subjects widi different apoE phenotypes during dietary sitostanol ester treatment. Journal of Lipid Research 34 1535-1544. [Pg.258]

While recombinant systems have greatly improved the drag discovery process, pathological phenotypes still are a step away from these drag testing systems. [Pg.18]

Completely different Physiological phenotype ligand relevant agon ism or... [Pg.180]

Table 9.2b). Increasing also is the list of phenotypes associated with these dimerization processes. With the emergence of receptor dimers as possible therapeutic targets have come parallel ideas with dimerized ligands (see Section 9.5). [Pg.183]


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See also in sourсe #XX -- [ Pg.2 , Pg.6 , Pg.92 , Pg.131 ]




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ATA-7, a Bleaching Phenotype

Acetylator phenotype

Adult phenotype

Albino phenotype

Antibiotic resistance phenotypic

Asian phenotypes

Asian phenotypes function

Assays high-content/phenotypic

Bacteria, lactic acid phenotypic

Behavioral phenotype

Biochemical Characteristics of Phenotypes

Biofilm phenotypes

Biofilm-specific phenotype

Biological Studies Phenotypic Screening for Antimitotic Effects

Biomaterial phenotypes

Biotransformation reaction phenotyping

CYP, reaction phenotyping

Cardiovascular phenotype

Chemokine phenotypes

Classic phenotypic screening

Clinical phenotypes

Clinical phenotypes genetic variation

Clinical phenotyping, importance

Cognitive phenotypes

Conjugation Phenotyping

Contractile phenotype

CpG island methylated phenotype

Dichotomous phenotype

Disease phenotype

Disruption phenotypes

Distribution and Phenotype

Dominant Mutant Phenotypes

Dopaminergic phenotype

Dose Individualization of Amonafide Based on N-Acetylator Phenotype

Drosophila phenotypes

Drug discovery reaction phenotyping

Drug phenotypic assays

Dwarf phenotype

Effector phenotypes, memory cells

Embryo lethal phenotype

Endothelial cell interactions Phenotypic modulation

Enzyme mapping phenotyping

Enzyme-based phenotyping tests

Evolution, phenotypic

Examples of Phenotypic Screens

Exceptional phenotypes

Extended phenotype

Faah-Knockout Phenotype

Flow phenotypic analysis

Functional phenotypes

G-protein coupled-receptor phenotypes

Genes and phenotypes

Genetic causes intermediate phenotypes

Genetic diseases phenotypic expression

Genetic diversity phenotypic variation, sources

Genome phenotype

Genome-wide association studies phenotypic traits

Genotype, and phenotype

Genotype-phenotype correlation

Genotype-phenotype coupling systems

Genotype-phenotype interaction

Genotype-phenotype linkages

Genotype-phenotype mapping

Genotypes phenotypes

Genotyping linking phenotype

Gilbert phenotype

Growth promotion and the tumour phenotype

High altitude phenotype

Human liver microsomes reaction phenotyping

Image-based phenotypic screen

Intermediate phenotypes

Intermediate phenotypes genetic studies

Keratin phenotypes

Knockout mice phenotyping

Knockouts cardiac phenotypes

Knockouts phenotypes, other

Knockouts vascular phenotypes

Lineage phenotype

Linking Genotype and Phenotype

Lymphocyte phenotypic markers

Lymphocytes phenotype

MDR phenotype

Malignant phenotype

Matching, phenotypic

Microglia phenotypes

Molecular phenotype

Molecular phenotyping

Molecule-phenotype association

Mutator phenotype

N -acetylator, phenotype

Nonradiolabeled Reaction Phenotyping

Optimal phenotype

Parasites/parasitism phenotype evolution

Parkinson phenotype

Permeases Phenotype

Pharmacogenetics phenotypes

Pharmacogenomic Pathways and Phenotypes

Phenol phenotype

Phenotype

Phenotype

Phenotype Screens

Phenotype behavior

Phenotype cancer

Phenotype carcinogenesis

Phenotype cells)

Phenotype characterization

Phenotype complexity

Phenotype mapping

Phenotype matching

Phenotype matching recognition alleles

Phenotype phenotypic response

Phenotype protein marker related

Phenotype self-reported

Phenotype space

Phenotype study techniques

Phenotype tests

Phenotype-based screens

Phenotypes Phenotypic variation

Phenotypes assay

Phenotypes cardiac

Phenotypes changes

Phenotypes characters

Phenotypes definition

Phenotypes hemodynamic

Phenotypes in Depression and Molecular Levels

Phenotypes other

Phenotypes phenotypic profiles

Phenotypes vascular

Phenotypes, relationship with cancer

Phenotypic

Phenotypic

Phenotypic Curing

Phenotypic Screen for Mitotic Inhibitors

Phenotypic Screening on iPSC-Derived Disease Models

Phenotypic adaptation

Phenotypic alterations

Phenotypic analysis

Phenotypic analysis, dominant

Phenotypic anchoring

Phenotypic and Genotypic Diagnosis of Malignancies. Muin S.A. Tuffaha

Phenotypic assay design

Phenotypic assay measured

Phenotypic assays

Phenotypic assays technology

Phenotypic cell-viability assay

Phenotypic characters

Phenotypic correction of immune response

Phenotypic disease-relevant phenotypes developed

Phenotypic diversity

Phenotypic diversity immunology

Phenotypic effect

Phenotypic high-content screening

Phenotypic markers

Phenotypic mass selection

Phenotypic modulation of endothelial cell

Phenotypic noise

Phenotypic plasticity

Phenotypic plasticity diversity

Phenotypic screen discovery

Phenotypic screen readout

Phenotypic screening

Phenotypic screens

Phenotypic sex

Phenotypic traits and

Phenotypic value

Phenotypic variability

Phenotypic variation

Phenotypic variation, molecular

Phenotypic-based drug discovery

Phenotypical identification

Phenotypical mixing

Phenotypically Unstable Mutants

Phenotyping

Phenotyping

Phenotyping approaches

Phenotyping clinical applications

Phenotyping of human immunodeficiency virus

Phenotyping patients

Phenotyping testing considerations

Polymer phenotypic selectivity

Poor Metabolizer Phenotype

Protein-Ligand Interactions phenotype

Proteomics phenotype

Quantitative In vitro Radiolabeled Reaction Phenotyping Studies

Quantitative Reaction Phenotyping Expressed or Purified Enzyme Systems

Radiolabeled Reaction Phenotyping

Reaction phenotyping

Reaction phenotyping appropriate

Reaction phenotyping correlation analysis

Reaction phenotyping defined

Reaction phenotyping processes

Reaction phenotyping protein concentration

Reaction phenotyping substrate concentration, selecting

Recessive phenotype

Relationship with genetic phenotype

Resistant phenotype, maintenance

Role of biofilm-specific phenotype

Schizophrenia clinical phenotype

Screening phenotype

Selection and Methods to Link Genotype with Phenotype

Serotonin transporter phenotypes

Signaling mechanism phenotypes

Skin cancer phenotype

Sterility phenotype

Synthetic phenotype

TPMT phenotyping

Target phenotypic screens

Terms Based on Phenotypic Consequences

The Missing Link—Adaptive Immunity Controls Microglia Phenotype Needed for Survival, Regrowth, and Renewal

Trait phenotypic

Transformation Phenotypic changes

Transparent testa phenotype

Transporter phenotyping

Tumour phenotype changes

Typical Phenotypic Assays

UGT Reaction Phenotyping

Vascular smooth muscle cells phenotypes

Wound response phenotype

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