Phenotypes definition

In close analogy with this biological definition, we will designate as molecular phenotype the ensemble of observable and computable properties of a chemical entity. These indeed are the observable expression of the core features of the... 

Fig. 1.5 Schematic representation of the evolution of life from its precursors, on the basis of the definition of life given by the authors. If bioenergetic mechanisms have developed via autonomous systems, the thermodynamic basis for the beginning of the archiving of information, and thus for a one-polymer world such as the RNA world , has been set up. Several models for this transition have been discussed. This phase of development is possibly the starting point for the process of Darwinian evolution (with reproduction, variation and heredity), but still without any separation between genotype and phenotype. According to the authors definition, life begins in exactly that moment when the genetic code comes into play, i.e., in the transition from a one-polymer world to a two-polymer world . The last phase, open-ended evolution, then follows. After Ruiz-Mirazo et al. (2004)...

Meyer UA. Genotype or phenotype the definition of a pharmacogenetic polymorphism. Pharmacogenetics 1991 1 66-67. 

W. T., Springer, T. A. (1985). The severe and moderate phenotypes of heritable Mac-1, LFA-1 deficiency Their quantitative definition and relation to leukocyte dysfunction and clinical features. J. Infect. Dis. 152,668-89. 

Loros We think there are some very subtle phenotypes in terms of fight-regulated gene expression. We are hoping definitive phenotypes may be easier to find in the WC knockout backgrounds. 

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