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Target phenotypic screens

Hart CP. Finding the target after screening the phenotype. Drug Discov Today 2005 10 513-9. [Pg.160]

Complexity and diversity are important characteristics of a library or compound collection as the eventual target of a compound in phenotypic screens can be any one of a multitude of diverse and complex proteins inside a ceU. Therefore, the overall design of the synthetic pathways in DOS should integrate both complexity and diversity. Structural complexity can, for instance, be generated in DOS through the use of tandem or domino reactions, processes involving a pair of... [Pg.188]

Undetermined targets uncovered through phenotype screening... [Pg.175]

Box 5.5 Some Methods Used for Target Identification in Phenotype Screening... [Pg.207]

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See also in sourсe #XX -- [ Pg.164 ]



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Phenotype

Phenotype/phenotyping

Phenotypic

Phenotypic screening

Phenotypic screens

Phenotyping

Screening target

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