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Phenotypic modulation of endothelial cell

Phenotypic modulation of endothelial cells in vitro Expression of adhesion molecules, growth factors and lytic factors. Adhesive properties of EC are not constant over time, and the normally nonadhesive endothelium becomes capable of binding neutrophils, lymphocytes and monocytes following cytokine-mediated activation after injury or inflammation, thus allowing for migration of these inflammatory cells into sites of pathological processes (Vachula and van Epps, 1992 Imhof and Dunon, 1995). [Pg.43]

Madri, J. A., Pratt, B. M., and Tucker, A. M. (1988) Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix. J. Cell. Biol. 106,1375-1384. [Pg.184]

Although HU may mediate some of its clinical benefits through its positive effect on HbF expression, these data also suggest that it may, by a yet-to-be defined mechanism of action, modulate the clinical severity of SCA. One possible pathway is that among the two incriminated interacting cell partners (sickle erythrocyte and endothelial cell) involved in vaso-adhesion and occlusion, HU may also affect the phenotype status of endothelial cells so that its adhesogenic (structural) and/or vasoregulatory (functional) properties are modified in a favorable manner. [Pg.239]


See other pages where Phenotypic modulation of endothelial cell is mentioned: [Pg.326]    [Pg.351]    [Pg.259]    [Pg.254]    [Pg.367]    [Pg.31]    [Pg.756]    [Pg.63]    [Pg.313]    [Pg.126]    [Pg.45]    [Pg.705]    [Pg.579]    [Pg.5]    [Pg.59]    [Pg.286]    [Pg.21]    [Pg.202]    [Pg.205]    [Pg.235]    [Pg.397]    [Pg.195]    [Pg.2204]    [Pg.279]    [Pg.397]    [Pg.211]    [Pg.360]   
See also in sourсe #XX -- [ Pg.43 , Pg.44 , Pg.45 , Pg.46 ]




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Endothelial

Endothelial cells

Endothelialization

Phenotype

Phenotype/phenotyping

Phenotypic

Phenotyping

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