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Surface cells

FIGURE 25 11 Diagram of a cell surface glycoprotein showing the disaccharide unit that IS recognized by an invading influenza virus... [Pg.1050]

A rather more specific mechanism of microbial immobilization of metal ions is represented by the accumulation of uranium as an extracellular precipitate of hydrogen uranyl phosphate by a Citrobacter species (83). Staggering amounts of uranium can be precipitated more than 900% of the bacterial dry weight Recent work has shown that even elements that do not readily form insoluble phosphates, such as nickel and neptunium, may be incorporated into the uranyl phosphate crystallites (84). The precipitation is driven by the production of phosphate ions at the cell surface by an external phosphatase. [Pg.36]

P-Endorphin. A peptide corresponding to the 31 C-terminal amino acids of P-LPH was first discovered in camel pituitary tissue (10). This substance is P-endorphin, which exerts a potent analgesic effect by binding to cell surface receptors in the central nervous system. The sequence of P-endorphin is well conserved across species for the first 25 N-terminal amino acids. Opiates derived from plant sources, eg, heroin, morphine, opium, etc, exert their actions by interacting with the P-endorphin receptor. On a molar basis, this peptide has approximately five times the potency of morphine. Both P-endorphin and ACTH ate cosecreted from the pituitary gland. Whereas the physiologic importance of P-endorphin release into the systemic circulation is not certain, this molecule clearly has been shown to be an important neurotransmitter within the central nervous system. Endorphin has been invaluable as a research tool, but has not been clinically useful due to the avadabihty of plant-derived opiates. [Pg.175]

EIA was originally developed as a histological technique to localize specific ceUular sites using the specificity of an immunological reaction (23). The resulting fluorescent antibodies can be detected in animal tissues at levels as low as 1 /tg/mL of body fluid. Eluorophore-labeled antibodies have also been used widely for flow cytometry appHcations using fluorescein antibodies to cell surface markers to detect and quantify specific cells (24). [Pg.26]

Biochemically, most quaternary ammonium compounds function as receptor-specific mediators. Because of their hydrophilic nature, small molecule quaternaries caimot penetrate the alkyl region of bdayer membranes and must activate receptors located at the cell surface. Quaternary ammonium compounds also function biochemically as messengers, which are generated at the inner surface of a plasma membrane or in a cytoplasm in response to a signal. They may also be transferred through the membrane by an active transport system. [Pg.378]

Food vitamin B 2 appears to bind to a saUvary transport protein referred to as the R-protein, R-binder, or haptocorrin. In the stomach, R-protein and the intrinsic factor competitively bind the vitamin. Release from the R-protein occurs in the small intestine by the action of pancreatic proteases, leading to specific binding to the intrinsic factor. The resultant complex is transported to the ileum where it is bound to a cell surface receptor and enters the intestinal cell. The vitamin is then freed from the intrinsic factor and bound to transcobalamin II in the enterocyte. The resulting complex enters the portal circulation. [Pg.113]

Tissue Uptake and Storage. Cell surface receptors take up the transcobalamin II—cobalamin complex, which is internalized into endosomes. The complex is dissociated and the transcobalamin II released. The mechanism by which cobalamin leaves the endosome is uncertain. [Pg.113]

The mechanism of inhibition has not been characterized, but it is probably related to the ionophoretic properties of these antibiotics. Monensin has been shown to inhibit the intracellular transport of viral membrane proteins of cells infected with Semliki Forest vims (169). The formation of syncytia, normally observed when T-lymphoblastoid cell line (CEM) cells are cocultivated with human immunodeficiency vims (HlV-l)-infected T-ceU leukemia cell line (MOLT-3) cells, was significantly inhibited in the presence of monensin (170). This observation suggests that the viral glycoproteins in the treated cells were not transported to the cell surface from the Golgi membrane. [Pg.172]

Considerable work has been done to try to explain why quats are antimicrobial. The following sequence of steps is beheved to occur in the attack by the quat on the microbial cell (/) adsorption of the compound on the bacterial cell surface (2) diffusion through the cell wall (J) binding to the cytoplasmic membrane (4) dismption of the cytoplasmic membrane (5) release of cations and other cytoplasmic cell constituents (6) precipitation of cell contents and death of the cell. [Pg.130]

Antiparallel beta (P) structures comprise the second large group of protein domain structures. Functionally, this group is the most diverse it includes enzymes, transport proteins, antibodies, cell surface proteins, and virus coat proteins. The cores of these domains are built up by p strands that can vary in number from four or five to over ten. The P strands are arranged in a predominantly antiparallel fashion and usually in such a way that they form two P sheets that are joined together and packed against each other. [Pg.67]

Many cell-surface receptors contain immunoglobulin-like domains. [Pg.318]

Many other cell-surface proteins involved in immunological recognition utilize immunoglobulin-like domains as structural elements. Immunoglobulin domains have been classified into five types, namely V (like antibody variable... [Pg.318]

Class 1 and class II MHC molecules bind peptide antigens and present them at the cell surface for interaction with receptors on T cells. The extracellular portion of these molecules consists of a peptide-binding domain formed by two helical regions on top of an eight-stranded antiparallel p sheet, separated from the membrane by two lower domains with immunoglobulin folds. These domains are differently disposed between the two protein subunits in class I and class II molecules. [Pg.320]


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Acetylcholine cell-surface

Adhesion, cell surface

Adsorption of microbial cells to surfaces

Alveolar epithelial cells surface area

Alveolar surface cells

Anti- Cell surface sugars

Antigen on the cell surface

Antigens cell surface sialic acid masking

Antigens, cell surface

Bacteria cell surface components

Bacteria cell-surface polysaccharides

Bacterial cell outer surface

Bacterial cell surface

Bacterial cell surfaces, alteration

Bacterial cell surfaces, highly reactive

Bacterial cell-surface proteins, interactions

Bacterial cell-surface proteins, interactions with antibodies

Basolateral cell membrane surfaces

Basolateral cell surface membrane receptors

Biotin cell surface receptors

Biotinylation cell surface

CELL SURFACE GLYCOLIPIDS

Cancer cell surface changes

Cancer immunity Cell surface proteins

Carbohydrate cell surface

Carbohydrates on Cell Surfaces

Cell (cont surface

Cell Surface Heparan Sulfate Proteoglycans

Cell Surface Reductases

Cell Surface of Bacteria

Cell culture growth surface

Cell fate control surface composition

Cell membranes surface receptors role

Cell proliferation surface receptors

Cell surface activation markers

Cell surface alterations

Cell surface alterations, mechanism

Cell surface alterations, mechanism resistance

Cell surface analytes, detection

Cell surface binding proteins, identification

Cell surface carbohydrates, in development

Cell surface carbohydrates, in development and diseases

Cell surface carbohydrates, recognition with

Cell surface display

Cell surface glycans

Cell surface glycans acid into

Cell surface glycans affinity

Cell surface glycans ligands

Cell surface glycoconjugates other glycoproteins

Cell surface glycoprotein

Cell surface glycosyltransferases

Cell surface hydrophobicity

Cell surface interactions

Cell surface labelling

Cell surface membrane, experimental

Cell surface modifications

Cell surface molecules

Cell surface molecules involved

Cell surface oligosaccharides

Cell surface oligosaccharides glycosylation process

Cell surface oligosaccharides metabolic oligosaccharide engineering

Cell surface polarity

Cell surface presentation, modified

Cell surface presentation, modified sialic acids

Cell surface proteins

Cell surface receptor dimerization

Cell surface receptor interactions

Cell surface receptor interactions cadherins

Cell surface receptor trafficking

Cell surface receptors

Cell surface receptors activation

Cell surface receptors and their ligands

Cell surface receptors antigenic

Cell surface receptors hormonal

Cell surface receptors recognition

Cell surface receptors structure

Cell surface receptors, biomaterials

Cell surface, effect

Cell surface, receptor/ligand binding

Cell surfaces periplasmic space

Cell surfaces, heparan sulfate

Cell walls surfaces

Cell-Surface Carbohydrates and Carbohydrate Vaccines

Cell-adhesive surfaces, biocompatibility

Cell-compatible surfaces

Cell-surface attachment

Cell-surface carbohydrate recognition

Cell-surface carbohydrate recognition binding

Cell-surface carbohydrate recognition interactions

Cell-surface carbohydrates, functions

Cell-surface dynamics, platelet

Cell-surface dynamics, platelet adhesion

Cell-surface elastin receptor

Cell-surface engineering

Cell-surface expression

Cell-surface glycoprotein modification

Cell-surface glycoproteins, glycosylation

Cell-surface glycosaminoglycan

Cell-surface immunoglobulins

Cell-surface interactions migration

Cell-surface ketones

Cell-surface lectin-reactive

Cell-surface receptor proteins

Cell-surface receptor proteins specificity

Cell-surface receptors, usage

Cell-surface thiols

Cell-surface, Lectin-reactive Glycoproteins

Cell-surface, isolation

Cell-type specific surface markers

Cells Cell surface receptors, drug

Cells, surface area/volume ratio

Cells, surface plasmon resonance

Charged surfaces cell response

Chemokine coated cell surfaces

Chemokine receptors cell-surface expression

Collagen cell surface binding

Columnar cells apical surface

Direct Cell-Surface Electron Transfer

Dopamine cell surface expression

Electrode reactions, fuel cells platinum surface

Endothelial Cell Surface Heparan Sulphate,

Endothelial cell interactions surface

Epidermal growth factor cell-surface receptors

Epithelial cell apical surfaces

Epithelial cells, ovarian surface

Epitope cell surface

Ethanol production yeast cell—surface engineering

Extracellular matrix cell culture surfaces

Flow cytometry cell surface markers

Fuel cells surface stability

Functions of Cell Surface Heparan Sulfate Proteoglycans

Future application of temperature-responsive cell culture surface to support and promote regenerative medicine field

GABA cell-surface

Glutamic cell surface structure

Glycans metabolically engineered, cell surface

Glycoconjugates, cell surface

Glycolipids cell surface labelling

Glycoproteins cell surface labelling

Glycosphingolipids cell-surface

Guanylyl cyclase cell-surface receptors

Hydrolysis cell surface

In cell surface

Integrin sequences, cell surface

Islet cell surface antibodies

Jurkat cell surfaces

Lipid cell surface

Living cells, surface energies

Macrophage cell surface antigen

Major histocompatibility markers cell surface antigens

Mammalian cell surfaces, analysis

Mammalian cells, surface modification

Membrane cell surface

Metal cell surfaces

Mitogen-activated protein kinase cell-surface receptors

Molecular cell surface membrane

Mucin-epithelial cell surfaces

Muscle cell surfaces

Muscle-cell surface chicken

Muscle-cell surface skeletal

Natural killer cell surface antigen

Open cell surface

Part-time Cell Surface Heparan Sulfate Proteoglycans

Peptidases cell-surface peptidase

Phage libraries cell surface selection

Phagocyte-Induced Exposure of PAMPS on the Fungal Cell Surface

Phosphatase alkaline, cell surface marker

Phosphatidylserine on the cell surface

Photoelectrochemical solar cells surface states

Photoresponsive surfaces cell adhesion, control

Physicochemical cell surface properties

Planar cell surface area

Polysaccharides as cell-surface antigens

Preparation cell surfaces

Protein interactions cell surface

Protein-Mediated Cell Adhesion on Biomaterial Surfaces

Proteins, cell surface display

Proteoglycans cell surface

Receptor at cell surfaces

Receptor on cell surfaces

Receptors Located on the Cells Surface

Regulating blood cell adhesion via surface modification of polyurethanes

Role of Cell Surface Carbohydrates in Development and Disease

Sandwich cell geometry, surface

Sialic Acid The Viral Cell-Surface Receptor Ligand

Sialic acids cell surface presentation

Signaling pathways binding, cell surface receptors

Subject cell surface

Sugars, cell surface

Surface Charge Characteristics of Blood Cells Using Mainly Electrophoresis and to a Limited Extent Sedimentation Potential Techniques

Surface SSFLC cells

Surface Structure-Other Than Cell Walls

Surface epithelial cells

Surface film cells

Surface migration cell

Surface nanotopography-cell interactions

Surface of cells

Surface potentials, Voltaic cells

Surface properties cells

Surface tension fuel cell

Surface tension, water cell wall

Surface treatments to enhance biocompatibility for stem cell culture

Surface unit cell

Switchable surfaces cell adhesion

Synapse cell-surface receptors

Temperature-responsive cell culture surface

Temperature-responsive cell culture surface characteristics

Temperature-responsive cell culture surface methods

The Masking of Cell-Surface Antigens by Sialic Acid

The Role of Cell Surface Carbohydrates in Cancer

Thermoresponsive cell culture surface

Transplantation, cell surface

Tumor cells surface

Tumor progression, cell surface carbohydrates

Virus, cell-surface receptor

Yeast cell—surface engineering

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