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Guanylyl cyclase cell-surface receptors

Schulz S. 1992. Guanylyl cyclase a cell-surface receptor throughout the animal kingdom. Biol Bull 183 155-158. [Pg.511]

The active (G-protein a-subunit)-GTP released in response to binding of 1 mol of hormone to the cell-surface receptor will activate adenylyl cyclase or guanylyl cyclase for as long as it contains GTP The hydrolysis to yield inactive (G-protein a-subunit)— GDP occurs only relatively slowly. Therefore, a single molecule of (G-protein a-subunit)-GTP will lead to the production of many thousands of mol of cAMP or cGMP as second messenger. [Pg.297]

Mammals have several classes of hormones, distinguishable by their chemical structures and their modes of action (Table 23-1). Peptide, amine, and eicosanoid hormones act from outside the target cell via surface receptors. Steroid, vitamin D, retinoid, and thyroid hormones enter the cell and act through nuclear receptors. Nitric oxide also enters the cell, but activates a cytosolic enzyme, guanylyl cyclase (see Fig. 12-10). [Pg.886]


See other pages where Guanylyl cyclase cell-surface receptors is mentioned: [Pg.178]    [Pg.49]    [Pg.29]    [Pg.40]    [Pg.565]    [Pg.384]    [Pg.424]    [Pg.235]   
See also in sourсe #XX -- [ Pg.179 ]




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