Photoresponsive surfaces cell adhesion, control

FIGURE 5.5.3 Control of cell adhesion on photoresponsive surfaces, (a) Access control of GRGDS peptides for biospecific cell adhesion by photoinduced cis-trans Isomerization of terminal azobenzene residues in grafted polymers (54). 

Another typical photoresponsive material for preparation of switchable surfaces is the spiropyran-merocyanine system. The spiropyran isomerizes to zwitterionic merocyanine conformation by UV exposure, and the reverse reaction can be triggered by irradiation with visible light as well as azobenzene. The changes in hydrophilic/hydrophobic properties through the isomerization of spiropyran groups also enable the control of cell adhesion/ detachment. Edahiro et al. reported photoresponsive cell culture substrates grafted... 

Edahiro, J. Sumaru, K. Tada, Y Ohi, K. Takagi, T. Kameda, M. Shinbo, T. Kanamori, T. Yoshuni, Y. In situ control of cell adhesion using photoresponsive culture surface. Biomacromolecules 2005, 6, 970-974. 

Edahiro, J. et al. (2005) In situ control of cell adhesion using photoresponsive culture surface. Biomacromolecules, 6, 970-974. 

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