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Genes regulator

In the 1980s, advances in biotechnology had a considerable impact on steroid research. During this period, the mechanism of steroid hormone-activated gene regulation became more clearly defined. These mechanistic studies stiH receive considerable attention in the primary Hterature. [Pg.414]

More than 30 years ago Jacob and Monod introduced the Escherichia coli lac operon as a model for gene regulation. The lac repressor molecule functions as a switch, regulated by inducer molecules, which controls the synthesis of enzymes necessary for E. coli to use lactose as an energy source. In the absence of lactose the repressor binds tightly to the operator DNA preventing the synthesis of these enzymes. Conversely when lactose is present, the repressor dissociates from the operator, allowing transcription of the operon. [Pg.143]

Another example is a recently discovered second mode of action by which nuclear receptors modulate transcription. In contrast to DNA-binding-dependent mechanisms, cross talk refers here to gene regulation by protein-protein-interaction of nuclear receptors with other transcription factors, such as AP-1 or NF-kB. Consequently, the nuclear receptor acts as a corepressor or coactivator of transcription. [Pg.397]

Turner BM (2001) Chromatin and Gene Regulation. Blackwell Science Ltd., Oxford... [Pg.595]

Burbach JP, Luckman SM, Murphy D et al (2001) Gene regulation in the magnocellular hypothalamo-neurohypophysial system. Physiol Rev 81 1197—1267... [Pg.1278]

Gene regulation by tocopherols has mainly been associated with PKC because of its deactivation by a-tocopherol and its contribution in the regulation of a number of transcription factors (NF-kappaB, API). A direct participation of the pregnane X receptor (PXR)/ retinoid X receptor (RXR) has been also shown. The antioxidant-responsive element (ARE) and the TGF-beta-responsive element appear in some cases to be implicated as well. The obser ved immunmodulatory function of a-tocopherol may also be attributed to the fact that the release of the proinflammatory cytokine interlukin-l 3 can be inhibited by a-tocopherol via... [Pg.1296]

Baler, R., Welch, W.J., Voellmy, R. (1992). Heat shock gene regulation by nascent polypeptides and denatured proteins hsp70 as a potential autoregulatory factor. J. Cell. Biol. 117, 1151-1159. [Pg.451]

Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS (2003) Expression profihng reveals off-target gene regulation by RNAi. Nat Biotechnol 21 635-637... [Pg.259]

McAdams HH, Arkin AP. Gene regulation towards a circuit engineering discipline. Curr Biol 2000 10 R318-R20. [Pg.159]

Small nuclear RNAs (snRNAs), a subset of these RNAs, are significantly involved in mRNA processing and gene regulation. Of the several snRNAs, Ul, U2, U4, U5, and U6 are involved in intron removal and the processing of hnRNA into mRNA (Chapter 37). The U7 snRNA may be involved in production of the correct 3 ends of histone mRNA—which lacks a poly(A) tail. The U4 and U6 snRNAs may also be required for poly(A) processing. [Pg.311]

All steps—from changes in DNA template, sequence, and accessibility in chromatin to RNA stability—are subject to modulation and hence are potential control sites for eukaryotic gene regulation. [Pg.357]

To date, this system provides the best understanding of the molecular events involved in gene regulation. [Pg.383]

GENE REGULATION IN PROKARYOTES EUKARYOTES DIFFERS IN IMPORTANT RESPECTS... [Pg.391]


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See also in sourсe #XX -- [ Pg.409 ]

See also in sourсe #XX -- [ Pg.11 , Pg.48 , Pg.304 , Pg.305 ]




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1,25-Dihydroxyvitamin gene regulation

A Potential Role of RORs in Xeno- and Endobiotic Gene Regulation

Androgen regulated gene

Androgens gene regulation

Breast cancer gene regulation

Contractile proteins tissue specific and developmentally regulated gene expression

Coordinately regulating multiple genes

Corticosteroids gene expression regulation

Cystic fibrosis transmembrane conductance regulator CFTR) gene

Cystic fibrosis transmembrane conductance regulator gene

Cystic fibrosis transmembrane regulator gene

Cystic transmembrane regulator gene

Early growth-regulated genes

Enteric bacteria gene regulation

Estradiol-regulated genes

Estrogen regulated genes

Estrogens gene regulation

Eukaryotics, gene regulation

Fatty acids, dietary gene expression regulation

GATA Gene Regulating Fat Body and Hemocyte Development

Gene Expression Is Also Regulated at the Levels of Translation and Polypeptide Processing

Gene Expression and Regulation

Gene Regulation Answers

Gene Regulation in Prokaryotes

Gene activity regulation

Gene expression auxin-regulated

Gene expression developmentally regulated

Gene expression light-regulation

Gene expression metal-regulated

Gene expression natural regulation

Gene expression negative regulation

Gene expression positive regulation

Gene expression regulators

Gene expression, regulation

Gene expression/regulation Transcription

Gene expression/regulation Translation

Gene expression/regulation attenuation

Gene expression/regulation basic-leucine zipper

Gene expression/regulation catabolite repression

Gene expression/regulation constitutive

Gene expression/regulation corepressors

Gene expression/regulation definition

Gene expression/regulation enhancers

Gene expression/regulation factors

Gene expression/regulation histones

Gene expression/regulation homeodomains

Gene expression/regulation levels

Gene expression/regulation ligand binding

Gene expression/regulation mediators

Gene expression/regulation methylation

Gene expression/regulation nuclear hormone receptors

Gene expression/regulation nucleosomes

Gene expression/regulation operon model

Gene expression/regulation posttranscriptional

Gene expression/regulation regulated

Gene expression/regulation tissue-specific

Gene expression/regulation transcriptional

Gene expression/regulation translational

Gene function, regulation

Gene regulation

Gene regulation

Gene regulation bacteria

Gene regulation epigenetic mechanisms

Gene regulation in eukaryotes

Gene regulation mammalian cells

Gene regulation mechanism

Gene regulation mechanisms activator

Gene regulation mechanisms positive

Gene regulation mechanisms repressor

Gene regulation prokaryotes

Gene regulation proteins

Gene regulation, development

Gene regulation, during

Gene transcription, regulation

Gene-Regulated Responses

Genes for Ribosomes Are Coordinately Regulated

Glucocorticoids gene regulation

Glucokinase gene, regulation

HIF as master regulator of hypoxia responsive gene expression

Hemopexin gene regulation

Histone methylation, gene regulation, and heterochromatin

Hypoxia-Regulated Gene Expression The EPAS-1 Story

Induction and Regulation of MT Gene Expression

Inflammatory genes, transcriptional regulators

Iron in redox-regulated and nitric oxide-induced gene expression

Lipogenic genes, regulation

Mechanisms of Gene Regulation in Eukaryotes

Mechanisms of gene regulation

Metabolic gene regulation principles

Metallothionein gene regulation

NO and Gene Regulation

Negative regulation of gene

Negative regulation of gene expression

Negative regulators, of gene expression

Nuclear receptor-regulated gene

Nuclear receptor-regulated gene transcription

Obese gene regulation

Other Metal-Regulated Genes

Phytoestrogens Up-regulate Antioxidant Genes

Post-Transcriptional Regulation of Gene Expression

Protein-Nucleic Acid Interactions as a Basis for Specific Gene Regulation

Redox- or Oxygen-Dependent Regulation of the EPO Gene

Regulating genes

Regulation and Polymorphisms in Phase II Genes

Regulation at the Gene Level

Regulation of Gene Expression

Regulation of Gene Expression How and Where A Schematic Overview

Regulation of Gene Expression in Prokaryotes

Regulation of Gene Expression with Pyrrole-Imidazole Polyamides

Regulation of Gene Rearrangement

Regulation of TH gene

Regulation of Tyrosine Hydroxylase Gene Expression by Hypoxia in Neuroendocrine Cells

Regulation of gene transcription by growth factors and cytokines

Regulation of gene transcription by hormones

Regulation of iNOS Gene Expression

Retinoic acid, gene transcription regulated

Retinoids gene regulation

Ribosome gene regulation

Secondary metabolites gene regulation

Shear stress gene expression regulated

Steroid hormones gene regulation

Stress activated protein kinases gene expression regulated

Stress responses gene regulation

Synthetic gene construction regulation

Temporal regulation, of genes

The Antioxidant Responsive Element and Phase II Gene Regulation

The Regulation of Gene Expression

Thyroid hormones gene regulation

Transcriptional Regulation of the TH Gene

Transcriptional regulation inducible nitric-oxide synthase gene

Transgenic mice gene regulation

Zinc — Lewis Acid and Gene Regulator

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