Gene regulation, development

Actinomycetes Large surface area to volume ratio should favour protein export Widely used in industrial microbiology Good expression systems being developed Promoters/gene regulation still poorly understood Rheology of fermentations important... 

The highly restricted tissue-specific transcription of c-mos poses an interesting problem in gene regulation during germ cell development. Moreover, c-mos is transcribed from different promoters in mouse spermatocytes and oocytes (Fig. 4) (Propst et al., 1987). In spermatocytes, transcription initiates approximately 280 nucleotides upstream of the c-mos ATG (Propst et al., 1987), whereas the transcription start site in oocytes has been mapped to 53 base pairs upstream of the ATG (Pal et al., 1991). Neither the spermatocyte nor oocyte promoter regions are... 

Hamdi HK, Nishio H, Tavis J, Zielinski R, Dugaiczyk A. Alu-mediated phylogenetic novelties in gene regulation and development. J Mol Biol 2000 ... 

Agger, K et al. (2007) UTX and JMJD3 are histone H3K27 demefhylases involved in HOX gene regulation and development Nature, 449, 731-734. 

Ling, X., Harkness, T.A., Schultz, M.C., Fisher-Adams, G. and Grunstein, M. (1996) Yeast histone H3 and H4 amino termini are important for nudeosome assembly in vivo and in vitro redundant and position-independent functions in assembly but not in gene regulation. Genes and Development, 10, 686-699. 

Loh, Y.H., Zhang, W Chen, X., George, J. and Ng, H.H. (2007) Jmjdla and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes and Development, 21, 2545—2557. 

Pasini, D., Hansen, K.H., Christensen, J., Agger, K., Cloos, P.A. and Helin, K. (2008) Coordinated regulation of transcriptional repression bythe RBP2 H3K4demethylase and Polycomb-Repressive Complex 2. Genes and Development, 22, 1345-1355. 

Boss, P.K., Davies, C., and Robinson, S.P., Analysis of the expression of anthocyanin pathway genes in developing Vitis vinifera L. cv. Shiraz grape berries and the implications for pathway regulation. Plant Physiol, 111, 1059, 1996. 

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