Gene expression transcriptional regulation

Kato Y, Kravchenko VV, Tapping RI, Han J, et al. 1997. BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. EMBO J. 16 7054-7066. 

MTP gene expression is transcriptionally regulated by dietary intake of fat, carbohydrate, and alcohol, as well as by insulin. The promoter region of the MTP gene contains elements... 

Tyystjarvi T, Maanpaa P, Mulo P et al. D1 Polypeptide degradation may regulate psbA gene-expression at transcriptional and translational levels in Synechocysds sp PCC-6803. Photosynth Res 1996 47 111-120. 

Chromosomal localization will be augmented (e.g., by the rep gene, which allows targeting to chromosome 19) and gene expression regulated by specific transcriptional control elements (6). (Reproduced with permission from Pergamon Press.)... 

Gene expression involves a few distinct and well-regulated steps. The first major step of gene expression involves transcription of a messenger RNA (mRNA) which is a RNA sequence complementary to the anti-sense deoxyribonucleic acid (DNA) strands, or, in other words, identical in sequence to the DNA sense strand, composing the gene. 

McGowan KM, Long SD, Pekala PH (1995) Glucose transporter gene expression regulation of transcription and mRNA stability. Pharmacol Ther 66 465-505... 

Polyadenylation is a critical posttranscriptional processing step in the maturation of eukaryotic mRNA [1], The location where the pre-mRNA is cleaved (also known as the poly(A) site) marks the end of a mRNA transcript. Many eukaryotic genes possess two or more poly(A) sites [2-4], and thus are involved in alternative polyadenylation (APA). APA is a powerful pathway that entails the selection of alternate poly(A) sites in a pre-mRNA and leads to the production of multiple mature mRNA isoforms from the same gene, resulting in potential gene expression regulation [1]. 

---