Prokaryotes vs, eukaryotes

See also Translation Overview, Eukaryotic vs Prokaryotic Translation, Figure 27.15, Stringent Response, Posttranscriptional Processing of rRNA and tRNA... 

See also Introns, Termination of Eukaryotic Transcription, Eukaryotic vs Prokaryotic T ranslation... 

See also Initiation of Translation, Structure of tRNAs, Structure of Prokaryotic mRNAs, Termination of Translation, Eukaryotic vs Prokaryotic Translation (from Chapter 28)... 

Abstract To understand how membrane-active peptides (MAPs) function in vivo, it is essential to obtain structural information about them in their membrane-bound state. Most biophysical approaches rely on the use of bilayers prepared from synthetic phospholipids, i.e. artificial model membranes. A particularly successful structural method is solid-state NMR, which makes use of macroscopically oriented lipid bilayers to study selectively isotope-labelled peptides. Native biomembranes, however, have a far more complex lipid composition and a significant non-lipidic content (protein and carbohydrate). Model membranes, therefore, are not really adequate to address questions concerning for example the selectivity of these membranolytic peptides against prokaryotic vs eukaryotic cells, their varying activities against different bacterial strains, or other related biological issues. 

Okazaki fragments are much smaiier in eukaryotes than in prokaryotes (about 200 nucieotides vs. 1,000 to 2,000). Because the size of eukaryotic Okazaki fragments are equivaient to the size of the DNA found in nucieosomes, it seems iikeiy that one nucieosome at a time may reiease its DNA for repiication. 

---