Regulation of Gene Expression How and Where A Schematic Overview

Regulation of Gene Expression How and Where A Schematic Overview 

The transfer of genetic information from the level of the nudeic add sequence of a gene to the level of the amino acid sequence of a protein or to the nudeotide sequence of RNA is termed gene expression. The entire process of gene expression in eucaryotes includes the following steps  

Biochemistry of Signal Transduction and Regulation. 3rd Edition. Gerhard Krauss Copyright 2003 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 3-527-30591-2 

Transcription of genes in mammals often initially produces a pre-mRNA, whose information content can be modulated by subsequent polyadenylation or splicing. Various final mRNAs coding for proteins with varying function and localization can be produced in this manner starting from a single primary transcript. 

The use of a particular mature mRNA for protein biosynthesis is also highly regulated. The regulation can occur via the accessibility of the mRNA for the ribosome or via the 

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