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Synthetic gene construction regulation

Gertz et aL investigated a library of synthetic promoters to construct a thermodynamic model that could accurately predict gene expression levels from promoter sequence in yeast. A thermodynamic model was built under the assumptions that gene regulation is controlled completely by DNA-protein and protein-protein interactions. The model calculates the probability that RNA polymerase binds to the promoter and then assumes that this results in gene transcription and protein production (Gertz et al. 2009). [Pg.195]

See other pages where Synthetic gene construction regulation is mentioned: [Pg.270]    [Pg.254]    [Pg.560]    [Pg.122]    [Pg.192]    [Pg.30]    [Pg.188]    [Pg.250]    [Pg.255]    [Pg.232]    [Pg.408]    [Pg.213]    [Pg.228]    [Pg.92]    [Pg.747]    [Pg.768]    [Pg.275]    [Pg.384]    [Pg.16]    [Pg.17]    [Pg.442]    [Pg.384]    [Pg.221]    [Pg.456]   
See also in sourсe #XX -- [ Pg.21 ]



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