Chromatography application

Direct property prediction is a standard technique in drug discovery. "Reverse property prediction can be exemplified with chromatography application databases that contain separations, including method details and assigned chemical structures for each chromatogram. Retrieving compounds present in the database that are similar to the query allows the retrieval of suitable separation conditions for use with the query (method selection). 

W. H. McFadden, Techniques of Combined Gas Chromatography Applications in Organic Analysis Wiley-Interscience, New York, 1973, pp. 158—164. 

Sepharose (e.g. Sepharose CL and Bio-Gel A) is a bead form of agarose gel which is useful for the fractionation of high molecular weight substances, for molecular weight determinations of large molecules (molecular weight > 5000), and for the immobilisation of enzymes, antibodies, hormones and receptors usually for affinity chromatography applications. 

R.E. Smith (Ed.), Ion Chromatography Applications, CRC Press, Boca Raton, 1988. ISBN 0849349672. 

Samuel, C., Davis, J.M. (2002). Statistical-overlap theory of column switching in gas chromatography application to flavor and fragrance compounds. Anal. Chem. 74, 2293. 

Bordajandi, L.R., Korytar, P., De Boer, J., Gonzalez, M.J. (2005). Enantiomeric separation of chiral polychlorinated biphenyls on P-cyclodextrin capillary columns by means of heart-cut multidimensional gas chromatography and comprehensive two-dimensional gas chromatography applications to food samples. J. Sep. Sci. 28, 163-171. 

A. Bronshtein, N. Aharonson, A. Turniansky, and M. Altstein, Sol-gel-based immunoaffinity chromatography application to nitroaromatic compounds. Chem. Mater. 12, 2050-2058 (2000). 

Explosive materials (explosives), 25 340. See also Explosives and propellants degree of hazard of, 13 155-156 hydrazine in, 13 597-598 cellulose ester applications, 5 403-404 liquid chromatography applications, 6 464... 

Foreign uranium resources, 17 522 Foreman and Veatch cell, 9 664 Forensic analysts, certification of, 12 95 Forensic biology, 12 102-104 Forensic chemistry, 12 89-104 physical evidence in, 12 90-95 Forensic laboratories, local and state, 12 98 Forensics, liquid chromatography applications, 6 465 Forensic science laboratories, 12 95 Forensic science, supercritical fluid extraction in, 24 14 Forensic testing, 12 95-104 Forensic toxicology, interpretation of results in, 12 98... 

Inertodetrinite, 6 707t Infant formula, liquid chromatography applications, 6 465... 

Liquid cathode lithium cells, 3 464-466 Liquid chromatography, 4 618—620 6 375, 440-468 14 233. See also High performance liquid chromatography Ion chromatography applications, 4 625-626 6 457-465 brief overview, 6 384-388 column switching, 6 446-447 columns, 4 623 derivatization, 6 447—448 detectors, 4 622-623 6 386-387, 448 52... 

Determination of risperidone and 9-hydroxyrisperi-done in human plasma by high-performance liquid chromatography Application to therapeutic drug monitoring in Japanese patients with schizophrenia. J Pharm Biomed Anal 19(3 ) 595-601. 

Another major ion chromatography application is the analysis of active ingredient counterions. Frequently, drug substances are formulated as salts in order to achieve specific pharmaceutical properties (such as improved solubility or control of dissolution rate). The analysis of... 

Schurig V. Enantiomer separation by complexation gas chromatography — Applications in chiral analysis of pheromones and flavours, in Schreier P (ed.), Bioflavour 87, Walter de Gruyter, Berlin, Germany, pp. 35—54, 1988. 

Aires-de-Sousa, J. and Gasteiger, J. (2002) Prediction of enantiomeric selectivity in chromatography. Application of conformation-dependent and conformation-independent descriptors of molecular chirality. J. Mol. Graphics Mod. 20, 373-388. 

Golderman L, Gellert J, Teschke R. 1983. Methods and Devices. Quantitative assessment of carbon tatrachloride levels in human blood by head-space gas chromatography application in a case of suicidal carbon tetrachloride intoxication. Intensive Care Medicine 9 131-135. 

---