Clinical liquid chromatography applications

Reinhardt TA, Horst RL, Orf JW, HoUis BW. A microassay for 1,25-dihydroxyvitamin D not requiring high performance liquid chromatography Application to clinical studies. J Clin Endocrinol Metab 1984 58 91-8. [Pg.1959]

Clinical. Liquid Chromatography Clinical Applications Pharmaceutical Applications. Microscopy Overview. Pharmaceutical Analysis Overview. Sensors Overview. [Pg.1416]

Gamiz-Gracia L, Garcia-Campana AM, Huertas-Perez JF, Lara FJ (2009) Chemiluminescence detection in liquid chromatography applications to clinical, pharmaceutical, environmental and food analysis-a review. Anal Chim Acta... [Pg.11]

Rapid Determination of Diazepam and Nordiazepam in Plasma by Electron Capture Gas-Liquid Chromatography. Application in Clinical Pharmacokinetic Studies... [Pg.273]

Lim CK, Peters TJ (1984) Urine and faecal porphyrin profiles by reversed-phase high-performance liquid chromatography in the porphyrias. Clin Chim Acta 139 55-63 Minder El, Vuilleumier JP, Vonderschmitt DJ (1992) Prototype application of robot in the clinical laboratory enabling fully automated quantification of fecal porphyrins. Clin Chem 38 516-521... [Pg.780]

An overview and discussion is given of literature methods published after 1989 devoted to the ion-interaction chromatographic determination of inorganic anions. Seventy references are quoted. Ion-interaction chromatography makes use of commercial reversed-phase stationary phase and conventional high-performance liquid chromatography instrumentation. The basis of the technique, the modification of the stationary phase surface, the choice of the ion-interaction reagent as well as the dependence of retention on the different variables involved are discussed. Examples of application in the fields of environmental, clinical and food chemistry are presented. The experimental conditions of stationary phase, of mobile phase composition as well as detection mode, detection limit and application are also summarized in tables. 1997 Elsevier Science B.V. [Pg.1198]

Lee KH, Ward BA, Desta Z, Flockhart DA (2003) Jones DR (2003) Quantification of tamoxifen and three metaoblites in plasma by high-performance liquid chromatography with fluorescence detection application to a clinical trial. J Chromatogr B 791 245-253... [Pg.139]

Beer B et al (2010) Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of tamoxifen, anastrozole, and letrozole in human plasma and its application to a clinical study. Anal Bioanal Chem 398 1791-1800... [Pg.248]

Zhu YB et al (2008) Optimizing high-performance liquid chromatography method with fluorescence detection for quantification of tamoxifen and two metabolites in human plasma application to a clinical study. J Pharm Biomed Anal 46 349-355... [Pg.249]

Electrospray ionization (ESI), a very powerful MS ionization mode, has been coupled with liquid chromatography becoming a popular tool in biomolecular analysis and drug analysis applications [1], Use of HPLC or ultra performance liquid chromatography (UPLC) combined with a mass spectrometry through the interface—ESI has become a powerful and routinely used analytical tool for many fields in scientific research, pharma industry, healthcare, and clinical diagnostic applications. [Pg.401]

Reversed-Phase Liquid Chromatography—Clinical Applications... [Pg.382]

Ion-Pair Liquid Chromatography—Environmental, Clinical, and General Applications... [Pg.384]

Since ISEs can be used in continuous flow systems or in flow systems with sample injection (flow injection analysis, FIA)21 their application is wide, not limited to discrete samples. Analysis time becomes shorter, with faster recycling. Additionally, in flow systems the experimental assembly and data analysis can be controlled automatically by microcomputer, including periodic calibration. Another development is the use of sensors for the detection of eluents of chromatographic columns in high-pressure liquid chromatography (HPLC). Miniaturization has permitted an increase in the use of sensors in foods, biological tissues, and clinical analyses in general. [Pg.308]

Baranowska, 1., Magiera, S., Baranowski, J. Clinical applications of fast liquid chromatography a review on the analysis of cardiovascular drugs and their metabolites. J. Chromatogr. B... [Pg.277]

Wang, X.-D., Li, J.-L., Lu, Y., Chen, X., Fluang, M., Chowbay, B., Zhou, S.-F. Rapid and simultaneous determination of nifedipine and dehydronifedipine in human plasma by liquid chromatography-tandem mass spectrometry Application to a clinical herb-drug interaction study. J. Chromatogr. B 852, 534—544 (2007)... [Pg.279]

In this review we examine improvements in column techniques, development of new separation media, and new applications of interest to the clinical chemist and biochemist. As a consequence of the wide nature of column chromatography, we have necessarily had to limit ourselves to fields where most progress has been made over the last few years. Thus we have confined ourselves mainly to affinity chromatography, gel chromatography, and high pressure liquid chromatography. [Pg.106]

Analysis is an integral part of research, clinical, and industrial laboratory methodology. The determination of the components of a substance or the sample in question can be qualitative, quantitative, or both. Techniques that are available to the analyst for such determinations are abundant. In absorption spectroscopy, the molecular absorption properties of the analyte are measured with laboratory instruments that function as detectors. Those that provide absorbance readings over the ultraviolet-visible (UV-vis) light spectrum are commonly used in high-performance liquid chromatography (HPLC). The above method is sufficiently sensitive for quantitative analysis and it has a broader application than other modes of detection. [Pg.1195]

E406 Adachi, Y., Inufusa, H., Yamashita, M., Kambe, A., Yamazaki, K., Sawada, Y. and Yamamoto, T. (1988). Clinical application of serum bilirubin fractionation by simplified liquid chromatography. Clin. Chem. 34, 385-388. [Pg.293]

Vogeser M. Liquid chromatography-tandem mass spectrometry-application in the clinical laboratory. [Pg.163]

The focus of this chapter is on quality assurance and quality control issues facing clinical laboratories, with emphasis on chromatographic analysis. Chromatography is a versatile analytical technique with diverse applications including gas chromatography (GC), liquid chromatography (LC), GC or LC coupled with mass spectrometry (MS) and other qualitative and quantitative bioanalytical methods. [Pg.1]

Liquid Chromatography with Inductively Coupled Plasma Mass Spectrometric Detection for Element Speciation Clinical and Toxicological Applications... [Pg.217]

In this chapter, the toxicologically and clinically relevant applications of liquid chromatography (LC) with inductively coupled plasma mass spectrometric (ICP-MS) detection are reviewed (a list of abbreviations used is given at the end of this chapter). After brief characterization of the analytical system, the speciation of arsenic, iodine, mercury, selenium and platinum is discussed. [Pg.218]

D7. Denton, M. S., Bostick, W. D., Dinsmore, S. R., and Mrochek, J. E., Continuously referenced, on-line monitoring of creatine kinase and lactate dehydrogenase isoenzymes for use in clinical diagnostics. In "Biological/Biomedical Applications of Liquid Chromatography H (G. L. Hawk, ed.), pp. 165-191. Dekker, New York, 1979. [Pg.288]

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