Mouse cell

Faruqi a.F., Egholm M., Glazer P.M. Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells. Proc. Natl Acad. Sci. USA 1998 95 1398-1403. 

C3T3 mouse cells (BALE cell transformation assay) Cell transformation No data (+) Tuetal. 1985... 

Shaw P., Held W. and Hastie N. (1983). The gene family for major urinary proteins, expression in several secretory tissues of the mouse. Cell 32, 755-761. 

May not work well in mouse cells Signal weak in U20S ... 

Spiegel, S., Yamada, K.M., Horn, B.E., Moss, J., and Fishman, P.FL (1985) Fluorescent gangliosides as probes for the retention and organization of fibronectin by ganglioside-deficient mouse cells. /. Cell Biol. 100, 721-726. 

Aniline transformed the Balb/3T3 mouse cell line at doses of 0.8 to 100 /dose-response effect), but not the Syrian hamster embryo cells (Dunkel et al. 1981). Results were negative in DNA damage assays in Escherichia coli (Mamber et al. 1983) and Bacillus subtilis (McCarroll et al. 1981). 

Bevacizumab, a recombinant, humanized monoclonal antibody, neutralizes vascular endothelial growth factor. The addition of bevacizumab to doublet chemotherapy is recommended in advanced NSCLC of nonsqua-mous cell histology in patients with no history of hemoptysis and no CNS metastasis who are not receiving therapeutic anticoagulation. 

Acetamides of type (83) derived from various /V-heterocycles have been prepared and investigated for antileukaemic activity in the German Democratic Republic. Within this series, the pyridazine derivative (84) was found to be the only active compound inhibiting the growth of L-1210 mouse cells in vitro (IDS0 10 4 mol/I) [297],... 

Since a monoclonal antibody is a fusion product of a malignant mouse cell and an antibody-producing cell, there is some concern about the safety of the production process itself (Petricciani, 1983). Methods for the production of monoclonal antibodies raise two general safety issues (1) the theoretical risk of transferring in the product factors associated with malignancy (e.g., oncogene factors) and (2) the use of animals for antibody production that are known to harbor a number of microbial agents some of which can produce diseases in humans. 

Maltzman, W. and h. Czyzyk, UV irradiation stimulates levels of p53 cellular tumor antigen in nontrans-formed mouse cells. Mol Cell Biol,... 

Marggraf, W.D., and Anderer, F.A., 1974, Alternative pathways in the biosynthesis of phosphatidylserine in mouse cells.Physiol. Chem. 335 1299-1304. 

Allen, J. D., Jackson, S. C., and Schinkel, A. H. (2002) A mutation hot spot in the BCRPl (ABCG2) multidrug transporter in mouse cell fines selected for doxorubicin resistance. Cancer Res. 62, 2294-2299. 

TABLE 3. In contrast to mouse cells, human cells expressing MuLVs do not form syncytia after M813 infection... 

MeCP2 Contains conserved MBD motif and a transcription repression domain Represses transcription from a methylated promoter in vitro and in vivo participates in several co-repressor complexes Sin3A/HDACl-2, NCoR/Ski, Rest/CoRest Expressed in somatic tissues and in embryonic stem (ES) cells co-localizes with heavily methylated satellite DNA in mouse cells... 

MBD4 Contains MBD domain and a repair domain (T-G mismatch glycosylase) Thymine glycosylase that binds to the product of deamination at methylated CpG sites Co-localizes with heavily methylated satellite DNA in mouse cells expressed in somatic tissues and in ES cells... 

Bernstein, B.E. et ol. (2005) Genomic maps and comparative analysis of histone modifications, in human and mouse. Cell, 120, 169-181. 

Bestor, T, Laudano, A., Mattaliano, R. and Ingram, V. (1988) Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. 

Mukherjee S, Trivedi P, Dorfman DM, Klein G, and Townsend A (1998) Murine cytotoxic T lymphocytes recognize an epitope in an EBNA-1 fragment, but fail to lyse EBNA-1-expressing mouse cells. J. Exp. Med. 187 445—450. 

Spielmann H, Pohl I, Doering B, Liebsch M, Moldenhauer E (1997) The embryonic stem cell test, an in vitro embryotoxicity test using two permanent mouse cell lines, 3 T3 fibroblasts and embryonic stem cells. In Vitro Toxicol 10 119-127... 

NT078 Makonkawkeyoon, S., P. Smitamana, C. Hirunpetcharat, and N. Manee-karn. Production of mouse immunoglobulin G by a hybrid plant derived from tobacco-mouse cell fusions. Ex-perientia 1995 51(1) 19-25. 

Benedict, W. E., N. Rucker, J. Eaust, and R. E. Kouri. Malignant transformation of mouse cells by cigarette smoke condensate. Cancer Res 1975 35 857. 

Isolation and characterization of monosomal mouse cell lines and interspecific hybrid cells with single mouse chromosomes... 

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