Mouse male germ cell

Nickel water-soluble salts were also reported to induce chromosome aberrations in CHO cells [444, 445] and in mouse mammary carcinoma cells [260, 446], Changes in growth control and chromosome aberrations in human bronchial cells were demonstrated in vitro after exposure to nickel sulphate the changes were insufficient to cause the cells to be tumourigenic [447], Nickel chloride was unable to produce chromosome aberrations in vivo in mammalian male germ cells [448],... 

Wang R-A,Nakane PK, Koji T. 1998. Autonomous cell death of mouse male germ cells during fetal and postnatal period. Biol. Reprod. 58 1250-56... 

Heinlein, U. A.O., Wallat, S., Senftleben, A., and Lemaire, L. (1994). Male germ cell-expressed mouse gene T AZ83 encodes a putative, cysteine rich transmembrane protein (cyritestin) sharing homologies with snake venom toxins and sperm egg fusion proteins. Dev. Growth and Diff. 36 49-58. 

De SK, McMaster MT, Dey SK, Andrews GK (1989) Cell-specific metallothionein gene expression mouse decidua and placentae. Development 107 611-621 De SK, Enders GC, Andrews GK (1991) High levels of metallothionein mRNAs in male germ cells of the adult mouse. Mol Endocrinol 5 628-636 Dorian C, Gattone II VH, Klaassen CD (1992) Renal cadmium deposition and injury as a result of accumulation of cadmium-metallothionein (Cd-MT) by the proximal convoluter tubules. Toxicol Appl Pharmacol 114 173-181 Dudley RE, Gammal LM, Klaassen CD (1985) Cadmium-induced hepatic and renal injury in chronically exposed rats likely role of hepatic cadmium-metallothionein in nephrotoxicity. Toxicol Appl Pharmacol 77 414-426 Ershoff BH (1948) Conditioning factors in nutritional disease. Physiol Rev 28 107-137... 

Mutter, G. L., and Wolgemuth, D. J. (1987). Distinct developmental patterns of c-mos protooncogene expression in female and male mouse germ cells. Proc. Nad. Acad. Sci. USA 84 5301-5305. 

Ponzetto, C., and Wolgemuth, D. J. (1985). Haploid expression of a unique c-abl transcript in the mouse male germ line. Mol. Cell. Biol. 5 1791-1794. 

Dominant lethal tests are usually conducted in mice or rats. The mouse dominant lethal test is more economical, but the rat dominant lethal test is more informative, as corpora lutea may be accurately enumerated in pregnant female rats, but not in mice, to assess preimplantation loss. Although dominant lethal tests may be performed with treated females, the tests are commonly performed with treated males in order to identify stages sensitive to mutation induction during germ cell development because the knowledge of stage sensitivity is important for risk evaluation. In a typical dominant lethal test, males... 

TABLE 1. Results of Experiments to Detect Chemically Induced Recessive Visible Mutations in Male Mouse Germ Cells by the Specific-Locus Method ... 

A, Leonard and Gh. Deknudt, The sensitivity of various germ-cell stages of the male mouse to radiation induced translocations. Can. J. Genet. Cytol. 10, 495—507... 

S. Qinghua, T. E. Schmid and I.-D. Adler, Griseofulvin-induced aneuploidy and meiotic delay in male mouse germ cells detected by using conventional cytogenetics and three-color FISH, Mutat. Res., 1999, 441, 181-190. 

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