Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

GABA

Aminobutanoic acid known as 7 aminobutync acid (GABA) it is a 7 amino acid and is involved in the transmission of nerve impulses... [Pg.1110]

PYRROLE AND PYRROLE DERIVATIVES] (Vol 20) g-aminobutyric acid [56-12-2] (GABA)... [Pg.42]

COALCONVERSIONPROCESSES - CLEANING AND DESULFURIZATION] (Vol 6) Gamma-aminobutyric acid (GABA)... [Pg.432]

Biological Activities and Analogues. Somatostatin exerts some neurotropic actions, eg, as a tranquilizer and as a spontaneous motor activity depressor. It also lengthens barbiturate anesthesia time and induces sedation and hypothermia. These actions are consistent with the strong association between somatostatin and GABA in the primate cerebral cortex, 90—95% of somatostatin-positive ceHs also contain GABA (100). [Pg.203]

AHopregnanolone and similar A-ring-reduced pregnanes potentiate GABA effects at these receptors. These steroids mimic the effects of the benzodiazepines, changing chloride ion conductance and producing sedative and hypnotic behavioral effects (276,277). Neuroactive steroids can be therapeutically useful as anticonvulsants, anxiolytics, or anesthetics (qv) (see also Hypnotics, sedatives, anticonvulsants, and anxiolytics). [Pg.222]

A newel class of hypnotic at the pieclinical stage as of this writing (ca 1993) are the neuiosteioids, also known as the epalons and represented by (30) (9), interact with the GABA /BZ receptor complex, have shown interesting activity in preclinical models (10), and are... [Pg.533]

Benzodiazepines. Several BZs have anticonvulsant activity and ate used for the treatment of epilepsy producing their anticonvulsant actions via interactions with the GABA /BZ receptor complex to enhance inhibitory GABAergic transmission (1). The anticonvulsant actions of the BZs tend to tolerate upon chronic usage in six months, and BZs also lead to withdrawal symptomatology. Other side effects include sedation, ataxia, and cognitive impairment. [Pg.535]

The oxa2ohdinedione trimethadione [127-48-0] C H NO (50), at one time the dmg of choice for the treatment of absence sei2ures, has been replaced by ethosuximide (41) and valproate (49). (50) has a distinct profile from that of phenytoin but causes photophobia and night blindness in approximately 30% of the patients taking it and has the CNS and sedative properties seen for other anticonvulsants together with moderate neutropenia, hepatitis, and skin rashes (13). Trimethadione does not appear to produce its effects via modulation of GABA-mediated responses. [Pg.537]

Nonbenzodiazepine Benzodiazepine Receptor Ligands. The simultaneous discovery of the molecular target for the BZs, the GABA /BZ receptor complex, by two teams of workers (34,35) resulted ia the identification of a number of atypical or anxioselective anxiolytics that, whereas not having the BZ pharmacophore, interacted direcdy with the central BZ receptor. The anxioselective nature of such agents was considered to be... [Pg.540]

Lindane is used predominately as a seed dressing and soil insecticide, for the control of ectoparasites of humans and domestic animals, for the control of locusts and grasshoppers, and as a residual spray to control the Anopheles vectors of malaria. Because of its relatively high volatility it is useful to control wood-boring insects of timber, fmit trees, and ornamental plants. The mode of action is not well understood but is thought to be competitive blocking of the y-aminobutyric acid (GABA) transmitter of synaptic nerve transmission. [Pg.277]

Mode of Motion. The cyclodienes, like lindane and toxaphene, affect the nerve axon produciag hyperactivity, convulsions, prostration, and death. The biochemical lesion is the competitive inhibition of the y-aminobutyric acid (GABA) neurotransmitter binding site of the nerve axon. Spray workers with lengthy exposure to dieldrin have suffered from prolonged and repeated central nervous system disturbances produciag epileptiform coavulsioas. Similar disturbances occurred ia workers heavily exposed to chlordecoae. [Pg.278]

Avermectins and Ivermectin. The avermectias are pentacycHc lactones isolated from fermentation products of Streptomjces avermitilis and ivermectin is a semisynthetic chemical, 22,23-dihydroavermectia (46). Ivermectin is effective in very low doses for the control of red spider mites on deciduous fmits, in baits for the control of imported fire ants, and as a parasiticide for Onchocerca volvulus in humans and for catde gmbs. These insecticides appear to function as agonists for the neuroinhibitory transmitter y-aminobutyric acid (GABA) (see Antiparasitic agents, avermectins). [Pg.297]

Table 10. GABA and GABA Receptor Agonists and Antagonists... Table 10. GABA and GABA Receptor Agonists and Antagonists...

See other pages where GABA is mentioned: [Pg.251]    [Pg.42]    [Pg.42]    [Pg.42]    [Pg.430]    [Pg.430]    [Pg.430]    [Pg.430]    [Pg.430]    [Pg.430]    [Pg.202]    [Pg.204]    [Pg.222]    [Pg.530]    [Pg.530]    [Pg.531]    [Pg.532]    [Pg.534]    [Pg.535]    [Pg.536]    [Pg.537]    [Pg.538]    [Pg.541]    [Pg.95]    [Pg.381]    [Pg.516]    [Pg.517]    [Pg.529]    [Pg.547]    [Pg.547]    [Pg.547]    [Pg.548]    [Pg.549]    [Pg.549]    [Pg.574]    [Pg.574]    [Pg.446]   
See also in sourсe #XX -- [ Pg.461 , Pg.478 ]

See also in sourсe #XX -- [ Pg.291 , Pg.292 , Pg.293 , Pg.294 , Pg.295 , Pg.296 , Pg.297 , Pg.298 , Pg.299 ]

See also in sourсe #XX -- [ Pg.210 , Pg.219 ]

See also in sourсe #XX -- [ Pg.24 , Pg.28 , Pg.190 ]

See also in sourсe #XX -- [ Pg.1793 ]

See also in sourсe #XX -- [ Pg.96 ]

See also in sourсe #XX -- [ Pg.18 , Pg.51 , Pg.53 , Pg.74 , Pg.76 ]

See also in sourсe #XX -- [ Pg.31 ]

See also in sourсe #XX -- [ Pg.1160 ]

See also in sourсe #XX -- [ Pg.243 ]

See also in sourсe #XX -- [ Pg.18 , Pg.80 , Pg.99 , Pg.113 , Pg.285 ]

See also in sourсe #XX -- [ Pg.419 ]

See also in sourсe #XX -- [ Pg.165 , Pg.240 , Pg.247 ]

See also in sourсe #XX -- [ Pg.165 , Pg.240 , Pg.247 ]

See also in sourсe #XX -- [ Pg.130 ]

See also in sourсe #XX -- [ Pg.30 , Pg.77 , Pg.135 ]

See also in sourсe #XX -- [ Pg.11 , Pg.25 , Pg.29 ]

See also in sourсe #XX -- [ Pg.392 ]

See also in sourсe #XX -- [ Pg.165 , Pg.240 , Pg.247 ]

See also in sourсe #XX -- [ Pg.55 , Pg.326 ]

See also in sourсe #XX -- [ Pg.23 ]

See also in sourсe #XX -- [ Pg.190 ]

See also in sourсe #XX -- [ Pg.13 , Pg.21 , Pg.25 , Pg.30 , Pg.84 , Pg.89 , Pg.514 , Pg.536 , Pg.537 , Pg.627 , Pg.782 , Pg.783 , Pg.787 ]

See also in sourсe #XX -- [ Pg.2 , Pg.3 , Pg.137 , Pg.138 , Pg.139 , Pg.239 ]

See also in sourсe #XX -- [ Pg.199 , Pg.200 ]

See also in sourсe #XX -- [ Pg.2 , Pg.3 , Pg.137 , Pg.138 , Pg.139 , Pg.239 ]

See also in sourсe #XX -- [ Pg.12 , Pg.91 , Pg.537 ]

See also in sourсe #XX -- [ Pg.776 ]

See also in sourсe #XX -- [ Pg.776 ]

See also in sourсe #XX -- [ Pg.73 ]

See also in sourсe #XX -- [ Pg.73 ]

See also in sourсe #XX -- [ Pg.505 ]

See also in sourсe #XX -- [ Pg.14 ]

See also in sourсe #XX -- [ Pg.400 ]

See also in sourсe #XX -- [ Pg.7 , Pg.146 , Pg.265 , Pg.376 ]

See also in sourсe #XX -- [ Pg.505 , Pg.512 ]

See also in sourсe #XX -- [ Pg.57 , Pg.58 ]




SEARCH



3-Isobutyl GABA

7-Acetylenic GABA

7-aminobutanoic acid (GABA

Agonists GABA receptors

Amino acid transmitters Aspartate, GABA, Glutamate

Antagonists of GABA

Antagonists, GABA

Anxiolytics GABA receptors

Ascaris GABA receptors

Autoradiographical localization, GABA

Barbiturates GABA receptors

Biological Functions of GABA

Brain GABA balance

Chloride channel, GABA receptor

Chloride channels GABA-gated

Depression GABA, role

Dieldrin insect GABA receptor

Drug GABA-agonists

Effect on GABA response

Electrophysiology, GABA receptors

Epilepsies GABA transmission

Epilepsy GABA receptors

GABA (gamma-aminobutyric

GABA (gamma-aminobutyric cells

GABA (y-aminobutyric acid

GABA -gated

GABA A

GABA Accumulation

GABA Dynamics

GABA Gabaculine

GABA R

GABA action

GABA activation

GABA aetiology of anxiety

GABA agonism

GABA agonist

GABA agonists and antagonists

GABA alcohol

GABA aminotransferase

GABA analog

GABA analogues

GABA anatomical distribution

GABA and

GABA and Depression

GABA and Parkinsons Disease

GABA anesthetics

GABA antagonists synthesis

GABA antiepileptic action

GABA antiepileptics

GABA anxiolytics

GABA as neurotransmitter

GABA benzodiazepines

GABA breakdown

GABA carbamazepine

GABA cell-surface

GABA cloning

GABA depolarization evoked

GABA depression

GABA discovery

GABA drug target

GABA from glutamic acid

GABA gated Cl-channels

GABA glycine receptors

GABA high affinity

GABA high affinity transporter

GABA hypotensive effect

GABA imaging

GABA inhibitors

GABA ion channels

GABA iontophoretic application

GABA lithium

GABA mammalian

GABA mania

GABA mechanisms

GABA membrane steroid receptors

GABA metabolism

GABA molecular biology

GABA neurons

GABA neurosteroids

GABA neurotransmitter, 12-13 (

GABA opioids

GABA production

GABA receptor acid derivatives

GABA receptor binding

GABA receptor ligand

GABA receptor protein

GABA receptor subunits

GABA receptors

GABA receptors GABAa

GABA receptors GABAb

GABA receptors and

GABA receptors antagonists

GABA receptors autoradiographic localization

GABA receptors benzodiazepine binding

GABA receptors benzodiazepines

GABA receptors binding sites

GABA receptors cerebellum

GABA receptors complex

GABA receptors cyclodiene toxicity

GABA receptors distribution

GABA receptors for

GABA receptors hypnotic drugs

GABA receptors isoforms

GABA receptors oocyte

GABA receptors partial allosteric modulators

GABA receptors pharmacology

GABA receptors presynaptic

GABA receptors striatal

GABA receptors structure

GABA receptors subtypes

GABA regulation

GABA release

GABA release during sleep

GABA reuptake inhibitor

GABA schizophrenia

GABA seizures

GABA site ligands

GABA storage

GABA structure

GABA subtypes

GABA superfamily

GABA synaptic transmission

GABA synthesis

GABA tea

GABA three-dimensional structure

GABA transamination

GABA transmission

GABA transport

GABA transporters

GABA types

GABA uptake

GABA uptake inhibitor

GABA valproate

GABA vesicular transporter

GABA, heterocyclic analogues

GABA, inhibition

GABA, receptor GABAA/benzodiazepine complex

GABA, y-amino butyrate

GABA- receptors, description

GABA-A ligands

GABA-A receptor ligands

GABA-A receptors

GABA-A receptors subunits

GABA-B receptor

GABA-T (

GABA-benzodiazepin-chloride channel

GABA-benzodiazepin-chloride channel receptor

GABA-benzodiazepine agonist drugs

GABA-ergic Compounds

GABA-ergic receptor

GABA-gated cation channels

GABA-rich Chlorella

GABA-shunt

GABA-transaminase

GABA-transaminase inhibitor

GABA-uptake inhibition

GABA/GABAergic

GABA/benzodiazepine receptor complex

GABAb receptor GABA release

Gamma-aminobutyric acid (GABA

Gamma-aminobutyric acid (GABA GABAa receptor

Gamma-aminobutyric acid (GABA sleep

Glutamate and AAT in GABA synthesis

Heterocyclic analogues of GABA

Inhibition by GABA

Inhibitor of GABA

Inhibitory postsynaptic potential GABA mediating

Insecticides Interfering with GABA-Gated Chloride Channels

Insects GABA receptors

Ionotropic GABA

Ionotropic GABA receptors

Manufacturing GABA tea

Metabolize GABA

Metabotropic GABA

Metabotropic glutamate receptors GABA release inhibition

Natural GABA agonists

Neurons GABA Norepinephrine

Neurotransmission GABA)

Neurotransmitters Include Norepinephrine, Acetylcholine, Dopamine, Serotonin, and GABA

Oxoglutarate Dehydrogenase and the y-Aminobutyric Acid (GABA) Shunt

P-Chlorophenyl GABA

Pantoyl GABA

Partial GABA agonist

Pathway for the Formation of GABA in Tea

Resistance GABA receptors

Reversal potential for GABA

Schizophrenia inhibitory GABA

Side Effects of GABA Boosting Medications

Sleep GABA)

Spiny cell local collaterals inputs (GABA and peptide)

Substantia nigra GABA neurons

Succinic acid from GABA

Synaptic transmission GABA release

Thiamin GABA shunt

Transamination of GABA

Turnover of GABA

Turnover of GABA by Infusion With Labeled Precursors

Tying a GABA from Copenhagen to Chicago The Chemistry of Tiagabine

Tyrosine GABA receptors

Use of GABA-T Inhibitors

Valerian GABA activity

Vertebrates GABA receptor subunits

Vinyl GABA

Y-Acetylenic-GABA

Y-Amino butyric acid (GABA

Y-Vinyl-GABA

© 2024 chempedia.info