Inhibitory postsynaptic potential GABA mediating

GABA receptors are divided into two main types GABAa and GABAB. inhibitory postsynaptic potentials in many areas of the brain have a fast and slow component. The fast component is mediated by GABAa receptors and the slow component by GABAB receptors. The difference in kinetics stems from the differences in coupling of the receptors to ion channels. GABAa... 

Ge S, Niesen CE. Beta-hydroxybutyrate potentiates GABA-A mediated inhibitory postsynaptic potentials in immature hippocampal CAl neurons. Epilepsia 1998 39 (Suppl 61 135. 

Although they interfere with the insect s nervous system their mode of action is different to that of organophosphates and carbamates and is novel. It involves inhibition of a-aminobutyric acid (GABA)-mediated inhibitory potentials as well as the excitatory postsynaptic potentials at the neuromuscular junction. This stops GABA-mediated nerves from regulating peripheral muscles. 

Ionotropic receptors are ligand-gated ion channels (left half of the table). The receptors for stimulatory transmitters (indicated in the table by a ) mediate the inflow of cations (mainly Na""). When these open after binding of the transmitter, local depolarization of the postsynaptic membrane occurs. By contrast, inhibitory neurotransmitters (GABA and glycine) allow cr to flow in. This increases the membrane s negative resting potential and hinders the action of stimulatory transmitters hyperpolarization, 0). 

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