GABA receptors cyclodiene toxicity

The data presented above show clearly that GABA receptors of mammalian brain are targets for the toxic action of cyclodiene, yBHC and pyrethroids. Although, the binding and flux assays, used so sucessfully to study interactions of these insecticides with mammalian brain, have had limited success when applied to insect tissues, there is ample evidence to suggest that GABA receptors of insects are targets for AVM (7, 21) cyclodienes and pyrethroids (17, 22). 

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