GABA high affinity transporter

Miller, J. W Kleven, D. T., Domin, B. A., and Fremau Jr., R. T. (1997) Cloned sodium-land chloride-) dependent high affinity transporters for GABA, glycine, proline, betaine, taurine, and creatine, in Neurotransmitter Transporters Structure, Function, and Regulation (Reith, M. E. A., ed.). Humana Press, Totowa, NJ, pp. 101-150. 

Larsson, O. M., Krogsgaard-Larsen, R, and Schousboe, A. (1980) High-affinity uptake of (RS)-nipecotic acid in astrocytes cultured from mouse brain. Comparison with GABA transport. J. Neurochem. 34, 970-977. 

Several GABA transporter proteins, that are active in the high-affinity uptake of... 

Roberts P J (1976) Gamma-aminobutyric acid homoexchange in sensory ganglia Brain Res 113, 206-209 Roskoski R (1978) Net uptake of L-glutamate and GABA by high-affinity synaptosomal transport systems / Neurochem 31, 493-498 Rubin R P (1970) The role of calcium in the release of neurotransmitter substances and hormones Pharmacol Rev 22, 389-498. 

Following the release of dopamine, the primary mode of removal from the synapse is reuptake into the presynaptic neuron via the dopamine transporter (DAT). DAT is dependent upon the energy created by the Na+/K+ pump and is a member of the Na+/Cl -dependent plasma membrane transporter family, as are the norepinephrine and 7-aminobutyric acid (GABA) transporters. Imaging studies utilizing compounds with highly specific affinity for DAT... 

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