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Depression GABA, role

GABA-B receptors. There is evidence that GABA-B receptors play a role in enhancing noradrenaline release in the cortex and in this respect differ fundamentally from the inhibitory GABA-A receptors which facilitate central GABAergic transmission. A decrease in the activity of GABA-B receptors may therefore contribute to the reduced central noradrenergic tone reported to occur in depression. [Pg.162]

Kalueff A, Nutt DJ (1997) Role of GABA in memory and anxiety. Depress Anxiety 4 100-110... [Pg.243]

Evidence from preclinical and clinical data suggests that GABA plays a role both in the pathophysiology of depression and bipolar disorder and in the mechanisms of action of antidepressant agents. - Low GABA concentrations and receptor activity in the brain cause depression, palpitation, insomnia, learning disorders, and memory failure. - GABA concentration in the CSF is inversely correlated with the severity of depression. ... [Pg.33]

See other pages where Depression GABA, role is mentioned: [Pg.28]    [Pg.317]    [Pg.403]    [Pg.571]    [Pg.183]    [Pg.291]    [Pg.892]    [Pg.893]    [Pg.85]    [Pg.184]    [Pg.67]    [Pg.115]    [Pg.515]    [Pg.794]    [Pg.9]    [Pg.410]    [Pg.115]    [Pg.68]    [Pg.79]    [Pg.323]    [Pg.184]    [Pg.365]    [Pg.358]    [Pg.359]    [Pg.252]    [Pg.461]    [Pg.2314]    [Pg.479]    [Pg.556]    [Pg.532]    [Pg.479]    [Pg.556]    [Pg.2864]    [Pg.2864]    [Pg.466]    [Pg.275]    [Pg.666]    [Pg.73]    [Pg.861]    [Pg.328]    [Pg.32]    [Pg.154]    [Pg.237]    [Pg.275]    [Pg.400]    [Pg.654]    [Pg.307]   
See also in sourсe #XX -- [ Pg.356 ]



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