Material Data Safety Sheets

To ensure safe working, material safety data sheets (MSDS) have to be consulted, particularly for the phosgenation reagents listed in Table 3.2, where the relevant risk and safety (R+S) phrases are presented. Further information can be found in the appropriate section of the relevant MSDS. 

A special report on phosgene toxicology and treatment is given in [14]. 

It has been estimated that one out of every four workers in the United States handles a chemical. Development of the material safety data sheet (MSDS) for each chemical is the responsibility of the chemical manufacturer. A typical material safety data sheet has nine or ten sections, as follows  

The general steps a laboratory worker must consider in planning an experiment are highlighted in the following paragraphs. The actual execution of each step is discussed in much greater detail in the following chapters. 

Following the philosophy described in Chapter 1, the development of a laboratory culture that empha 

1 Chapter 3 Evaluating Hazards and Assessing Risks in the Laboratory 

Complete assessment of hazards should be made for all materials and suspected products associated with the experiment or procedure. Chapter 3 provides the basis for interpreting and applying much of the available hazard information. Both literature resources and knowledgeable contacts inside the local research community and in other institutions can provide additional information. If risks are determined to be unacceptable, experiments can be redesigned to minimize the volumes of chemicals used or to employ less hazardous alternatives that might do the job equally well. Some important considerations include volumes and flow rates to be employed, amounts required, physical properties of materials to be used, potential for exposure, regulatory concerns, and emergency response for unexpected events. 

The Material Safety Data Sheet (MSDS) for each hazardous chemical is one of the resources that should be incorporated into experiment planning. However, because of the inconsistent quality of information found in MSDSs, Laboratory Chemical Safety Summaries (LCSSs), which are compiled in Appendix B, should be consulted or developed for the materials involved. In any case, the experiment planner needs to be aware that the existing regulations do not necessarily represent the full complement of prudent practices for handling hazardous materials and that other input is therefore essential. 

---

Great Lakes Chemical Corp., information summarized from Material Safety Data Sheets. 

To an experienced operator trained in the handling of industrial chemicals, the dimers present Httle cause for concern in handling or storage. The finished polymer coating presents even less of a health problem contact with the reactive monomer is unlikely. In the ancillary operations, such as cleaning or adhesion promotion, the operator must observe suitable precautions. Before using the process chemicals, operators must read and understand the current Material Safety Data Sheets, which are available from the manufacturers. 

When processed and used according to manufacturer s recommendations, acetal resins present no extraordinary health risks. Before the use of any plastic material, including acetal, the Material Safety Data Sheet (MSDS) appHcable to the grade in question should be consulted. 

Dimethylacetamide, Material Safety Data Sheet, E.I. du Pont de Nemours and Co., Inc., Wilmington, Del., 1988. 

Material Safety Data Sheets (MSDS) issued by suppHers of acetone ate requited to be revised within 90 days to include new permissible exposure limits (PEL). Current OSHA PEL (54) and ACGIH threshold limit values (TLV) (55) ate the same, 750 ppm TWA and 1000 ppm STEL. Eot comparison, the ACGIH TWA values for the common mbbing alcohols are ethyl, 1000, and isopropyl, 400 ppm. A report on human experience (56) concluded that exposure to 1000 ppm for an 8-h day produced no effects other than slight, transient irritation of the eyes, nose, and throat. 

C depending on the reference consulted). Fires may be controlled with carbon dioxide or dry chemical extinguishers. Recommended methods of handlings loadings unloadings and storage can be obtained from Material Safety Data Sheets and inquiries directed to suppHers of acetone. 

A.crolein, Material Safety Data Sheet, Union Carbide Chemicals and Plastics Company Inc., Specialty Chemicals Division, August 15,1989. 

Material Safety Data Sheet ISlumherl386, BP Chemicals Inc., Cleveland, Ohio, 1989. 

P. Igoe, D. Wilson, and W. Silverman, Material Safety Data Sheet No. 400 in Genum s Reference Collection, Genum Publishing Corp., Schenectady, N.Y., 1989. 

Material Safety Data Sheet C41, Trimethjhlpropane, Elake Celanese Canada Inc., Montreal, 1990. 

In general, the acute toxicity of halogenated flame retardants is quite low. Tables 11—14 contain acute toxicity information from various manufacturers material safety data sheets (MSDS) for some of the flame retardants and intermediates Hsted in the previous tables. The latest MSDS should always be requested from the suppHer in order to be assured of having up-to-date information about the toxicity of the products as well as recommendations regarding safe handling. 

Material safety data sheets from Ethyl Corp. (EC) and Great Lakes (GL). Product data sheet from Dead Sea Bromine. 

Material safety data sheets from Dover Chemical (D), Occidental Chemical Corp. (OC), and Velsicol Chemical Co. (V). ... 

Nocolok 100 Flux, Material Safety Data Sheet, Alcan Aluminum Corp., Apr. 1986. 

Mercury salts are highly toxic and must be handled carefliUy. It is necessary to consult the material safety data sheet prior to handling. Strict adherence to OSHA/EPA regulations is essential. The ACGIH adopted (1991—1992) TLV for mercury as inorganic compounds is TWA 0.1 mg/m and for fluorides as F 2.5 mg/m. ... 

Human and environmental welfare for lubricants and their use is addressed in Material Safety Data Sheets (MSDS). These MSDS address toxicology and health concerns based on the components in the lubricant as well as indicating the proper response in case of a spik. Environmental ha2ards of the lubricant are covered on European and Japanese MSDS as shown in Table 5. 

AH Department of Transportation (DOT), Environmental Protection Agency (EPA), and Occupational Safety and Health Act (OSHA) rules and regulations should be reviewed prior to handling hydrochloric acid and all the regulations must be followed. AH employees handling HCl must be trained to ensure that they are familiar with the appropriate materials safety data sheets and appHcable regulations. 

Occupational Safety and Health J ct. OSHA regulations deal principally with physical aspects of safety and those things generally associated with accident prevention. These federal regulations deal especially with the need for estabHshed material safety data sheets and the proper labeling of printing inks under the Hazard Communication Laws. 

Material Safety Data Sheet, Keduced Iron, MaUinkrodt Specialty Chemicals Co., Paris, Ky., Jan. 1993. 

The latest government regulations set forth under the Toxic Substances Control Act and in PubHc Health Service pubHcations should be checked before formulating new lubricants. Users of lubricants should request Material Safety Data Sheets for each substance involved plus certification of compliance from vendors. Lubricant compounders should insist on similar information from their suppHers for any additive packages. Manufacturers of both additives and lubricants commonly make toxicity checks on commercial products. 

Erom Material Safety Data Sheets from commercial suppliers ia parentheses. 

Niobium BaseMlloy Powders Material Safety Data Sheet, No. 516, Teledyne Wab Chang Corp., Albany, Oieg., 1992. 

Material Safety Data Sheets (MSDS) and the organic peroxides producers recommendations should be followed carefljlly for handling and storage of organic peroxide compositions. 

Material Safety Data Sheet, Amoco TA-33, Amoco Chemical Co., Chicago, hi., Dec. 1993. 

Table 2 Hsts some of the physical, toxicity, flammabiUty, and reactivity properties of common chemicals (10,13,42,45—51). Also given are some of the quantities specified for reporting spills and for compliance with legislated requirements. The OSHA regulations require that material safety data sheets (MSDS) be developed for all process materials, so that the ha2ard data can be communicated to employees (52). Characteristics of toxicity, flammabiUty, chemical iastabiUty, reactivity and reaction energy, operatiag coaditioas, and corrosive properties of constmction materials must all be considered ia analy2iag ha2ard poteatials of chemicals and chemical operations.

Nylon 6,6 Material Safety Data Sheet, Du Pont, Wilmington, Del., rev. Eeb. 19,1991 technical data. Sigma-Aldrich Corp., Milwaukee, Wis. 

---