Material Safety and Data Sheet

Various medical devices based on Terathane have been approved by the U.S. FDA, including those used within the body. Formulators are cautioned, however, that FDA approval is not given genericaHy for these devices it must be appHed for separately by each manufacturer for each device. Additional data on safety of PTMEG may be found in the material safety and data sheets provided by the manufacturers. 

Terathane Polyether Glycols, Material Safety and Data Sheet, E. I. du Pont de Nemours Co., Inc., Wilmington, Del., 1991. 

Safety glasses must be worn in the laboratory at all times. Material safety and data sheets should be read prior to the start of the experiment. All chemicals should be considered hazardous from a standpoint of flammability and toxicity. Appropriate safety gloves must be worn when using organic solvents so that no skin contact is permitted. Care must be taken to use organic solvents either in a well-ventilated area or in a hood. Avoid breathing the fumes or sources of electrical sparks. The GPC instrument, including solvent reservoir and waste container, should be vented to a fume hood or other exhaust system. 

MSDS-CCOHS. 1992. Mineral spirits. Material Safety and Data Sheet-Canadian Center for Occupational Health and Safety. May 13, 1992. 

A PA is granted for a fixed period of five years after which time it must be renewed. Renewal applications should be addressed to the renewals section of the 1MB. An IMB renewal form should be submitted together with additional material. Three copies of the following are required SPC plus one electronic copy a chronological list of variations since last renewal or authorisation labels PIL and data sheet for the professions (if any). Two copies of the following should be provided Periodic Safety Update additional clinical or toxicity data (if any) quality defect reports updated stability data and updated manufacturer s authorisation. 

The ability, when known, of a chemical (e.g., ethers) to formtmstable and potentially explosive peroxides or to cause polymerization. When polymerization inhibitors are known or recommended, they have been included. According to National Safety Council Data Sheet 1-655/rev. 1982, peroxides can be rendered harmless with iron(II) sulfate (1 1) or by passing the liquid material over a bed of activated aluminum oxide [-alumina (OSHA)]. 

Inventory of material sa Qr data sheets for chemicals present in the area for Occupational Safety Health Act and Emergen Planning and Community Right Co Know Act compliance... 

To an experienced operator trained in the handling of industrial chemicals, the dimers present Httle cause for concern in handling or storage. The finished polymer coating presents even less of a health problem contact with the reactive monomer is unlikely. In the ancillary operations, such as cleaning or adhesion promotion, the operator must observe suitable precautions. Before using the process chemicals, operators must read and understand the current Material Safety Data Sheets, which are available from the manufacturers. 

When processed and used according to manufacturer s recommendations, acetal resins present no extraordinary health risks. Before the use of any plastic material, including acetal, the Material Safety Data Sheet (MSDS) appHcable to the grade in question should be consulted. 

Material Safety Data Sheets (MSDS) issued by suppHers of acetone ate requited to be revised within 90 days to include new permissible exposure limits (PEL). Current OSHA PEL (54) and ACGIH threshold limit values (TLV) (55) ate the same, 750 ppm TWA and 1000 ppm STEL. Eot comparison, the ACGIH TWA values for the common mbbing alcohols are ethyl, 1000, and isopropyl, 400 ppm. A report on human experience (56) concluded that exposure to 1000 ppm for an 8-h day produced no effects other than slight, transient irritation of the eyes, nose, and throat. 

C depending on the reference consulted). Fires may be controlled with carbon dioxide or dry chemical extinguishers. Recommended methods of handlings loadings unloadings and storage can be obtained from Material Safety Data Sheets and inquiries directed to suppHers of acetone. 

A.crolein, Material Safety Data Sheet, Union Carbide Chemicals and Plastics Company Inc., Specialty Chemicals Division, August 15,1989. 

P. Igoe, D. Wilson, and W. Silverman, Material Safety Data Sheet No. 400 in Genum s Reference Collection, Genum Publishing Corp., Schenectady, N.Y., 1989. 

In general, the acute toxicity of halogenated flame retardants is quite low. Tables 11—14 contain acute toxicity information from various manufacturers material safety data sheets (MSDS) for some of the flame retardants and intermediates Hsted in the previous tables. The latest MSDS should always be requested from the suppHer in order to be assured of having up-to-date information about the toxicity of the products as well as recommendations regarding safe handling. 

Material safety data sheets from Ethyl Corp. (EC) and Great Lakes (GL). Product data sheet from Dead Sea Bromine. 

Material safety data sheets from Dover Chemical (D), Occidental Chemical Corp. (OC), and Velsicol Chemical Co. (V). ... 

Mercury salts are highly toxic and must be handled carefliUy. It is necessary to consult the material safety data sheet prior to handling. Strict adherence to OSHA/EPA regulations is essential. The ACGIH adopted (1991—1992) TLV for mercury as inorganic compounds is TWA 0.1 mg/m and for fluorides as F 2.5 mg/m. ... 

Human and environmental welfare for lubricants and their use is addressed in Material Safety Data Sheets (MSDS). These MSDS address toxicology and health concerns based on the components in the lubricant as well as indicating the proper response in case of a spik. Environmental ha2ards of the lubricant are covered on European and Japanese MSDS as shown in Table 5. 

AH Department of Transportation (DOT), Environmental Protection Agency (EPA), and Occupational Safety and Health Act (OSHA) rules and regulations should be reviewed prior to handling hydrochloric acid and all the regulations must be followed. AH employees handling HCl must be trained to ensure that they are familiar with the appropriate materials safety data sheets and appHcable regulations. 

Occupational Safety and Health J ct. OSHA regulations deal principally with physical aspects of safety and those things generally associated with accident prevention. These federal regulations deal especially with the need for estabHshed material safety data sheets and the proper labeling of printing inks under the Hazard Communication Laws. 

The latest government regulations set forth under the Toxic Substances Control Act and in PubHc Health Service pubHcations should be checked before formulating new lubricants. Users of lubricants should request Material Safety Data Sheets for each substance involved plus certification of compliance from vendors. Lubricant compounders should insist on similar information from their suppHers for any additive packages. Manufacturers of both additives and lubricants commonly make toxicity checks on commercial products. 

National Safety Council 444 North Michigan Avenue Chicago, Id. 60611 Industrial safety data sheets on materials and materials handling and safe operation of equipment and processes. 

Material Safety Data Sheets (MSDS) and the organic peroxides producers recommendations should be followed carefljlly for handling and storage of organic peroxide compositions. 

Table 2 Hsts some of the physical, toxicity, flammabiUty, and reactivity properties of common chemicals (10,13,42,45—51). Also given are some of the quantities specified for reporting spills and for compliance with legislated requirements. The OSHA regulations require that material safety data sheets (MSDS) be developed for all process materials, so that the ha2ard data can be communicated to employees (52). Characteristics of toxicity, flammabiUty, chemical iastabiUty, reactivity and reaction energy, operatiag coaditioas, and corrosive properties of constmction materials must all be considered ia analy2iag ha2ard poteatials of chemicals and chemical operations.

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