Material Safety Data Sheet updating

An overall review of the management of change documentation package should be performed to ensure documentation update items (including material safety data sheets) are addressed and that PHA action items are complete. This can be done by one person but is often best achieved by a PSSR Team. The process needs to account for ... 

Also, if you obtain new information or test data about products or hazards, make sure you convey this information to your customers by way of updated material safety data sheets (MSDSs) and product information. 

A product-specific material safety data sheet (MSDS) is prepared for each product that has been formulated for a customer. Any time a change in the formula or an ingredient substitution is made in that product, a new update of the MSDS information is performed. In addition, the customer is notified that the original product has changed and the new MSDS is the document that should be consulted for product health, safety, and environmental information. The most current product MSDS then accompanies each shipment of product from the manufacturing facility. 

Material Safety Data Sheet. 2001. Acetic anhydride. Mallinnckrodt Baker, Inc., New Jersey (updated 2007). 

Major elements of a CHP plan include listing of responsibilities for employers, employees, and a chemical hygiene officer. Also among the items that have to be covered in the plan is the stipulation that every laboratory must have a complete chemical inventory that is updated annually. A copy of the Material Safety Data Sheet (MSDS), which defines each chemical as toxic, carcinogenic, or dangerous, must be on file and readily accessible and available to aU employees 24 hours a day, 7 days a week. The MSDS contains important information for the benefit of laboratory employees. The chemical manufacturer s information as supplied on the MSDS is used to ascertain whether a certain chemical is hazardous. Each MSDS must give the product s... 

Chemical manufacturers or importers shall ensure that distributors and manufacturing purchasers of hazardous chemicals are provided an appropriate material safety data sheet with their initial shipment, and with the first shipment after a material safety data sheet is updated. The chemical manufacturer or importer shall either provide material safety data sheets with the shipped containers or send them to the manufacturing ptirchaser prior to or at the time of the shipment. If the material safety data sheet is not provided with the shipment, the manufacturing purchaser shall obtain one from the chemical manufacturer, importer, or distributor as soon as possible. 

Distributors shall ensure that material safety data sheets, and updated information, are provided to other distributors and manufacturing purchasers of hazardous chemicals. 

The review team will determine if all documentation such as P IDs and material safety data sheet (MSDS) have been updated. 

Hazardous material (HAZMAT)-. Effective HMIS (hazardous material identification system) and MSDS (material safety data sheet) programs are both essential elements of a safety program The HMIS system identifies and labels substances that may pose some hazard to those who use them. The MSD sheets, provided by the suppliers of materials deemed to be hazardous, are kept on file to quickly identify all hazards and the appropriate responses in emergency situations. This mandated part of a safety program can be handed off to a subteam that ensures the MSDS database in updated and the HMIS labeling program is audited for compliance. 

Graf provided updated recommendations in a paper in an article published in 1966. Material Safety Data Sheets are provided by the manufacturer when perchloric acid is purchased. An excellent summary of safety practices is given in the Internet reference at the end of this section. The recommendations from these and other sources are combined and summarized below. 

In addition, in response to users of Prudent Practices 1981 who have emphasized the value of the information on how to handle compounds that pose special hazards, the committee has compiled Laboratory Chemical Safety Summaries (Appendix B) that provide chemical and toxicological information for 88 substances commonly found in laboratories. Although most of the information provided for these compounds will maintain its value, data on some properties, especially toxicological ones, should be updated frequently. Accordingly, the most recent Material Safety Data Sheets provided by the manufacturer or other updated sources should be consulted before work is done with hazardous compounds. 

Many authors used government and company websites as sources for updated Material Safety Data Sheets (MSDS) and information on the threshold limit values (TLV) for the airborne concentration of filler dusts in the workplace. Reliable information on possible risks to human health or the environment is extremely important to current and potential users of existing fillers, or new fillers of different origin and different particle size/shape characteristics. It should be recognized that health issues have been responsible in the past for the withdrawal from certain plastics markets of natural and synthetic fibrous fillers with unique properties such a as chrysotile asbestos, microfibers, whiskers and the recently mandated very low content of crystalline silica in mineral fillers. 

The MPIs should be dated and updated in a controlled manner. The MPIs should also include the appropriate materials safety data sheets (MSDSs) for the materials being used. In many cases the MPIs should be reviewed with the R D staff that have been involved in writing the specifications to ensure that mistakes are not made. The R D staff should be included in process review meetings for the same reason (see Appendix A). In some cases, MPIs and specifications must be written from an existing process. Care must be taken that the operators reveal all of the important steps and parameters to the person documenting the process. 

A PA is granted for a fixed period of five years after which time it must be renewed. Renewal applications should be addressed to the renewals section of the 1MB. An IMB renewal form should be submitted together with additional material. Three copies of the following are required SPC plus one electronic copy a chronological list of variations since last renewal or authorisation labels PIL and data sheet for the professions (if any). Two copies of the following should be provided Periodic Safety Update additional clinical or toxicity data (if any) quality defect reports updated stability data and updated manufacturer s authorisation. 

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