Cytomegalovirus interferons

Dalod M, Hamilton T, Salomon R, et al. Dendritic cell responses to early murine cytomegalovirus infection subset functional specialization and differential regulation by interferon alpha/beta. J Exp Med 2003 197(7) 885-898. [Pg.100]

Cheeseman SH, Rubin RH, Stewart JA, Tolkoff-Rubin NE, Cosimi AB, Cantell K, Gilbert J, Winkle S, Herrin JT, Black PH, Russell PS, Hirsch MS. Controlled clinical trial of prophylactic human-leukocyte interferon in renal transplantation. Effects on cytomegalovirus and herpes simplex virus infections. N Engl J Med 1979 300(24) 1345-9. [Pg.1842]

Human diploid cell lines have been utilized classically as in vitro hosts for the propagation of polio, mumps, rubella, cytomegalovirus, varicella-zoster, rabies, hepatitis A, respiratory syncytial virus, parainfluenza and many other viruses. Other uses in the biotechnology industry include large-scale cultivation for the production of various cellular products, such as human interferon beta. [Pg.259]

Human Cytomegalovirus Hepatitis C Virus Hepatitis Delta Virus Human Herpes Virus-6 Human Immunodeficiency Virus Herpes Simplex Virus Interferons... [Pg.556]

ORF, open-reading frame NA, not available KS, Kaposi s sarcoma KSHV, Kaposi s sarcoma-associated herpesvirus GPCR, G protein-coupled receptor CMV, cytomegalovirus MCMV, mouse cytomegalovirus MCK, murine cytomegalovirus chemokine CCL5, CC chemokine ligand 5 IFN, interferon IL, interleukin NF-kB, nuclear factor kB Tp, T helper NK, natural killer. [Pg.85]

Cytokine responsive gene 2 Cytotoxic T lymphocyte Dendritic cell Epidemic polyarthritis Formalin-inactivated RSV Fractalkine Gamma interferon Glycosaminoglycans Heparin-binding domains Herpes simplex virus Human cytomegalovirus Human herpesvirus Human immunodeficiency virus Human leukocyte antigen Interferon... [Pg.119]

Compels UA, Macaulay HA (1995) Characterization of human telomeric repeat sequences from human herpesvirus 6 and relationship to replication. J Gen Virol 76 451-458 Goodbourn S, Didock L, Randall RE (2000) Interferons cell signalling, immune modulation, antiviral responses and viral countermeasures. J Gen Virol 81 2341-2364 Hengel H, Flohr T, Hammerling GJ, Koszinowski UH, Momburg F (1996) Human cytomegalovirus inhibits peptide translocation into the endoplasmic reticulum for MHC class I assembly. J Gen Virol 77 2287-2296... [Pg.20]

Zhu H, Cong JP, Shenk T (1997) Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs induction of interferon-responsive RNAs. Proc Natl Acad Sci USA 94 13985 13990... [Pg.21]

Borysiewicz LK, Rodgers B, Morris S, Graham S, Sissons JG (1985) Lysis of human cytomegalovirus infected fibroblasts by natural killer cells demonstration of an interferon-independent component requiring expression of early viral proteins and characterization of effector cells. J Immunol 134 2695-2701... [Pg.125]

Darnell JE Jr, Kerr IM, Stark GR (1994) Jak-Stat pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264 1415-1421 David M (1995) Transcription factors in interferon signaling. Pharmacol Ther 65 149-161 Davignon J-L, Castanie P, Yorke JA, Gautier N, Clement D, Davrinche C (1996) Anti-human cytomegalovirus activity of cytokines produced by CD4+ T-cell clones specifically activated by lEl peptides in vitro. J Virol 70 2162-2169 Doherty P (1995) Immunity to viruses. The Immunologist 3 231-233... [Pg.166]

Gribaudo G, Ravaglia S, Caliendo A, Cavallo R, Gariglio M, Martinotti MG, Landolfo S (1993) Interferons inhibit onset of murine cytomegalovirus immediate-early gene transcription. Virology 197 303-311... [Pg.167]

Jonjic S, Pavic I, Lucin P, Rukavina D, Koszinowski UH (1990) Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes. J Virol 64 5457 5464 Joseph J, Knobler RL, Lublin FD, Hart MN (1991) Mouse hepatitis virus (MHV-4, JHM) blocks gamma interferon-induced major histocompatibility complex class H antigen expression on murine cerebral endothelial cells. J Neuroimmunol 33 181 190... [Pg.167]

Lucin P, Jonjic S, Messerle M, Polic B, Hengel H, Koszinowski UH (1994) Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor. J Gen Virol 75 101-110... [Pg.168]

Schindler C, Shuai K, Prezioso VR, Darnell JE (1992) Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257 809-813 Scholz M, Hamann A, Blaheta RA. Auth MK, Encke A, Markus BH (1992) Cytomegalovirus- and interferon-related effects on human endothelial cells cytomegalovirus infection reduces upregulation of HLA class II antigen expression after treatment with interferon-gamma. Hum Immunol 35 230-238... [Pg.169]

Schut RL, Gekker G, Hu S, Chao CC, Pomeroy C, Jordan MC, Peterson PK (1994) Cytomegalovirus replication in murine microglial cell cultures suppression of permissive infection by interferon-gamma. J Infect Dis 169 1092-1096... [Pg.169]

IL-8 also acts on nonleukocytic cells such as melanoma cells and synovial fibroblasts (16) in vitro. IL-8 enhances viral replication, particularly cytomegalovirus, in human fibroblasts in vitro (7 7). IL-8 significantly inhibits the antiviral activities of interferon-a (18). IL-8 also increases the adhesion to unstimulated human umbilical cord vein endothelial cells (HU VECs) (19), enhances transendothelial migration (20), and induces angiogenesis in rat cornea (21). [Pg.70]

To date the antiviral activity of interferon has been demonstrated only in tissue culture or in animal systems and not in man. In one study (16) interferon Induced by measles vaccine was found not to affect the shedding of cytomegalovirus of chronically infected children. However, this was not unexpected since this virus is highly resistant to the effect of interferon in tissue culture. [Pg.116]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...