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Human cytomegalovirus

Stuyver LJ, McBrayer TR, Thamish PM, Qark J, HoUecker L, Lostia S, Nachman T, Grier J, Bennett MA, Xie M-Y, Schinazi RE, Morrey JD, Inlander JL, Eurman PA, Otto MJ (2006) Inhibition of hepatitis C repUcon RNA synthesis by P-D-2 -deoxy-2 -fluoro-2 -C-methylcytidine a specific inhibitor of hepatitis C virus replication. Antiviral Chem Chemother 17 79-87 Sullivan V, Talarico CL, Stanat SC, Davis M, Coen DM, Biron KK (1992) A protein kinase homo-logue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells. Nature 359 85... [Pg.83]

Xiong X, Smith JL, Chen MS (1997) Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation. Antimicrob Agents Chemother 41 594-599... [Pg.84]

Darke PL, Cole JL, Waxman L, Hall DL, Sardana MK, Kuo LC (1996) Active human cytomegalovirus protease is a dimer. J Biol Chem 271 7445-7449 De Francesco R, Carfi A (2007) Advances in the development of new therapeutic agents targeting the NS3 A serine protease or the NS5B RNA-dependent RNA polymerase of the hepatitis C virus. Adv Drug Deliv Rev 59 1242-1262... [Pg.104]

Margosiak SA, Vanderpool DL, Sisson W, Pinko C, Kan CC (1996) Dimerization of the human cytomegalovirus protease kinetic and biochemical characterization of the catalytic homodimer. Biochemistry 35 5300-5307... [Pg.106]

Tong L, Qian C, Massariol MJ, Bonneau PR, Cordingley MG, Lagace L (1996) A new serine-protease fold revealed by the crystal structure of human cytomegalovirus protease. Nature 383 272-275... [Pg.109]

In this chapter, we have described the spectrum of antiviral activities that have been discovered beyond the world of nucleoside analogues, protease and fusion inhibitors. The compounds and mechanisms described here may one day add significantly to the armamentarium of antiviral agents, not only against Herpes Simplex, Hepatitis B and Human Immunodeficiency Virus, but also against Hepatitis C and Human Cytomegalovirus. [Pg.170]

Bogner E (2002) Human cytomegalovirus terminase as a target for antiviral chemotherapy. Rev Med Virol 12 115-127... [Pg.171]

Chee MS, Bankeir AT, Beck S, Bohni R, Brown CM, Cerny R, Horsnel T, Hutchinson CAI, Kouzarides T, Martignetti JA, Preddie E, Satchwell SP, Tomlinson P, Weston KM, Barrel BG (1990) Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169, Curr Top Microbiol Immunol 154 125-170 Chiu TK, Davies DR (2004) Structure and function of HIV-1 integrase. Curr Top Med Chem 4 965-977... [Pg.171]

Ealagas ME, Paya C, Ruthazer R, Badley A, Patel R, Wiesner R et al. (1998) Significance of cytomegalovirus for long-term survival after orthotopic liver transplantation a prospective derivation and validation cohort analysis. Transplantation 66 1020-1028 Field AK (1999) Human cytomegalovirus challenges, opportunities and new drug development. Antivir Chem Chemother 10 219-232... [Pg.172]

Harada K, Eizuru Y, Isashiki Y, Ihara S, Minamishima Y (1997) Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir. Arch Virol 142 215-225... [Pg.172]

Hwang J-S, Bogner E (2002) ATPase activity of the terminase subunit pUL56 of human cytomegalovirus. J Biol Chem 27 6943-6948... [Pg.173]

Sarasini A, Baldanti F, Furione M, Percivalle E, Brerra R, Barbi M et al (1995) Double resistance to ganciclovir and foscamet of 4 human cytomegalovirus strains recovered from AIDS patients, J Med Virol 47 237-244... [Pg.174]

Underwood M, Harvey R, Stanat S, Hemphill M, Miller T, Drach J, Townsend L, Biron K (1998) Inhibition of human cytomegalovirus DNA maturation by a benzimidazole ribonucleoside is mediated through the UL89 gene product. J Virol 72 717-725 Van Maele B, Debyser Z (2005) HlV-1 integration an interplay between HIV-1 integrase, cellular, and viral proteins. AIDS Rev 7 26 3... [Pg.175]

Jiwa, N. M., etal. (1989). Rapid detection of human cytomegalovirus DNA in peripheral blood leukocytes of viremic transplant recipients by the polymerase chain reaction. Transplantation 48,... [Pg.233]

Nolte, F. S., et al. (1995). Early detection of human cytomegalovirus viremia in bone marrow transplant recipients by DNA amplification. J. Clin. Microbiol. 33,1263-1266. [Pg.234]

Toyama, R. and Okayama, H. (1990) Human chorionic gonadotropin alpha and human cytomegalovirus promoters are extremely active in the fission yeast Schizosaccharomyces pombe. FEBS Letters, 268 (1), 217-221. [Pg.56]

Kenzelmann M et al. Transcriptome analysis of fibroblast cells immediate-early after human cytomegalovirus infection. J Mol Biol 2000 304 741-751. [Pg.115]

Chamber J et al. DNA microarrays of the complex human cytomegalovirus genome profiling kinetic class with drug sensitivity of viral gene expression. J Virol 1999 73 5757-5766... [Pg.115]

L. Authier, C. Grossiord, P. Brossier, and B. Limoges, Gold nanoparticle-based quantitative electrochemical detection of amplified human cytomegalovirus DNA using disposable microband electrodes. Anal. Chem. 73, 4450-4456 (2001). [Pg.479]

Human cytomegalovirus glycoprotein B Tobacco seed gB-specific antigenic activity. - 42, 96... [Pg.145]

The problem of quality control in donor blood and blood products is of great importance for a health service in practice. Among infectious agents that contaminate blood, mention should be made of human immunodeficiency vims, hepatitis B and C vimses, and human cytomegalovirus (Ender, 2004 Mohr, 2000). In the past decade, the role of... [Pg.107]

Gao, J. L., Murphy, P. M. (1994) Human cytomegalovirus open reading frame Us28 encodes a functional beta-chemokine receptor. J. Biol. Chem. 269, 28539-28542. [Pg.180]

Pleskoff, O., Treboute, C., Brelot, A., Heveker, N., Seman, M., and Ahzon, M. (1997) Identification of a chemokine receptor encoded by human cytomegalovirus as a cofactor for HIV-1 entry. Science 276, 1874-1878. [Pg.180]

Bein, G., Bitsch, A., Hoyer, J., and Kirchner, H. (1991) The detection of human cytomegalovirus immediate early antigen in peripheral blood leucocytes. J. Immunol. Meth. 137, 175-180. [Pg.70]

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