Nuclear factors

NF-kB is a family of pleiotropic transcription factors that regulate the expression of a wide variety of genes. These genes are involved in various biological functions 

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Regulatory proteins Insulin Somatotropin Thyrotropin lac repressor NEl (nuclear factor 1) Catabolite activator protein (CAP) API... 

Renin-Angiotensin-Aldosterone System ACE Inhibitors Nuclear Factor-icB... 

Nuclear Factor Kappa B Toll-like Receptors... 

NF-IL6 is a nuclear factor for interleukin-6, a transcription factor which is activated by IL-6 and other cytokines and stimulates stress protein gene expression. 

Nuclear factor of activated T cells cytosolic NFATc... 

Nuclear factor kappa B (NF-kB) is the generic term for a family of dimeric eukaryotic transcription factors, composed of members of the Rel family of DNA-binding proteins including the mammalian proteins RelA (or p65), cRel, RelB, p50 and p52, and the Drosophila proteins Dorsal, Dif and Relish. These proteins bind with different affinities to a consensus DNA sequence motif (called the kB site) consisting of the sequence 5 -GGGRNNYYCC-3 in which R is a purine, Y is a pyrimidine, and N is any base. 

Nuclear Factor of Activated T Cells Cytosolic NFATc... 

The Rel homology domain (RHD) is an evolutionarily conserved domain found in some eukaryotic transcription factors, including NF-kB, the nuclear factors of activated T-cells (NFATs) and the drosophila proteins Dif and Relish. Some of these transcription factors form... 

Essential for induction ofthe/Z-5 gene in inflammatory reactions is the binding site for nuclear factor kappa B (NF-kB). NF-kB responds to cytokines, stress, free radicals, ultraviolet irradiation, and bacterial, viral, or even parasitic antigens [2]. NF-kB stands for a family of subunits, which form homo-, and heterodimers. All NF-kB proteins share a highly conserved DNA-binding/dimerization domain called the Rel homology domain (RHD) consisting of two (3-strand core domains... 

Hoffmann A, Baltimore D (2006). Circuitry of nuclear factor kappaB signaling. Immunol Rev 210 171-186. 

Modulation of rat intestinal nuclear factor NF-kappaB by gum arabic. Rat small intestine by gum arabic. Digestive Diseases and Sciences, Vol. 53, No. 1, (May 2007), pp 80-87, ISSN 0163-2116. 

EPR studies on electron transfer systems where neighboring centers are coupled by spin-spin interactions can yield useful data for analyzing the electron transfer kinetics. In the framework of the Condon approximation, the electron transfer rate constant predicted by electron transfer theories can be expressed as the product of an electronic factor Tab by a nuclear factor that depends explicitly on temperature (258). On the one hand, since iron-sulfur clusters are spatially extended redox centers, the electronic factor strongly depends on how the various sites of the cluster are affected by the variation in the electronic structure between the oxidized and reduced forms. Theoret-... 

Romanelli A., Pedone C., Saviano M., Bianchi N., Borgatti M., Mischiati C., Gambari R. Molecular interactions between nuclear factor B (NF-kB) transcription factors and a PNADNA chimera mimicking NF-kB binding sites. Eur. J. Biochem. 2001 268 6066-6075. 

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