Supplemental unit

Iron Ore Statistics 1993 Supplement, United Nations Conference on Trade and Development, Geneva, Switzerland, 1993. 

USP DI and Supplements, United States Pharmacopeial Convention, Washington, D.C., 1998. 

There are three classes of SI units base, derived, and supplemental units. A base unit was decreed by the CGPM for each of eight fundamental but dimensionally independent physical quantities. These units are listed in Table 1-2. A derived unit is derived mathematically from two or more base units (Table 1 -3). A supplemental unit is a unit that conforms to the SI but that has not been classified as either base or derived. At present only the radian (for plane angles) and the steradian (for solid angles) are classified this way. 

The OPLS atom types are a superset of the AMBER united atom types and the bonding parameters are just those of AMBER, supplemented where needed by the OPLS developers. The bond stretch, angle bending, dihedral angle and improper dihedral angle terms are identical to those of AMBER. Unlike AMBER, different combination rules are used for the van der Waals parameters, no hydrogen bonding term is used and no lone pairs are used. 

Soybean meal is the most frequently used source of supplemental protein in the United States (5). Cottonseed meal is another important protein supplement. Both meals are by-products from oil extraction of the seeds. Canola meal is derived from rapeseed low in emcic acid [112-86-7] and glucosinolates. Linseed (derived from flax seed), peanut, sunflower, safflower, sesame, coconut, and palm kernel meals are other sources of supplemental protein that are by-products of oil extraction (4). 

United States International Trade Commission (USITC), Synthetic Organic Chemicals—United States Production and Sales, 1990, pubhcation 2470, Washington, D.C., Dec. 1991 R. F. Bradley, A. Leder, and Y. Sakuma, Fluorocarbons, ia Chemical Economics Handbook, SRI latematioaal, Menlo Park, Calif., 1990, sections 543.7000—543.7003, plus 1992 supplemental data. 

The demonstration unit was later transported to the CECOS faciHty at Niagara Falls, New York. In tests performed in 1985, approximately 3400 L of a mixed waste containing 2-chlorophenol [95-57-8] nitrobenzene [98-95-3] and 1,1,2-trichloroethane [79-00-5] were processed over 145 operating hours 2-propanol was used as a supplemental fuel the temperature was maintained at 615 to 635°C. Another 95-h test was conducted on a PCB containing transformer waste. Very high destmction efficiencies were achieved for all compounds studied (17). A later bench-scale study, conducted at Smith Kline and French Laboratories in conjunction with Modar (18), showed that simulated chemical and biological wastes, a fermentation broth, and extreme thermophilic bacteria were all completely destroyed within detection limits. 

Since 1960, portable stone-processing plants have grown steadily. Although such units are relatively small, companies utilize them to supplement the permanent facilities at times of peak demand or to provide stand-by capacity. 

This excess hydrogen is normally carried forward to be compressed into the synthesis loop, from which it is ultimately purged as fuel. Addition of by-product CO2 where available may be advantageous in that it serves to adjust the reformed gas to a more stoichiometric composition gas for methanol production, which results in a decrease in natural gas consumption (8). Carbon-rich off-gases from other sources, such as acetylene units, can also be used to provide supplemental synthesis gas. Alternatively, the hydrogen-rich purge gas can be an attractive feedstock for ammonia production (9). 

Fluid mixing is a unit operation carried out to homogenize fluids in terms of concentration of components, physical properties, and temperature, and create dispersions of mutually insoluble phases. It is frequently encountered in the process industry using various physical operations and mass-transfer/reaction systems (Table 1). These industries include petroleum (qv), chemical, food, pharmaceutical, paper (qv), and mining. The fundamental mechanism of this most common industrial operation involves physical movement of material between various parts of the whole mass (see Supplement). This is achieved by transmitting mechanical energy to force the fluid motion. 

PermeOx is also used to improve the bioremediation of soils contaminated with creosote or kerosene (see Bioremediation (Supplement)), to deodori2e sewage sludges and wastewater (see Odormodification), and to dechloriaate wastewater and effluents. A special formulation of calcium peroxide, made by FMC and sold ia the United States under the trademark Trap2ene, is used for removing metal ions from acidic waste streams such as coal ash leachate and acid mine drainage (see Wastes, industrial). 

Wet Process. Over 90% of the phosphoric acid produced, both in the United States and worldwide, is wet-process phosphoric acid used almost exclusively for agricultural appHcation as both fertilizers and animal feed supplements. Although constituting a small proportion of the total wet-acid production, a significant amount of phosphoric acid for food and technical appHcations is made by purification of wet-process acid. 

An estimation of the amount of amino acid production and the production methods are shown ia Table 11. About 340,000 t/yr of L-glutamic acid, principally as its monosodium salt, are manufactured ia the world, about 85% ia the Asian area. The demand for DL-methionine and L-lysiae as feed supplements varies considerably depending on such factors as the soybean harvest ia the United States and the anchovy catch ia Pern. Because of the actions of D-amiao acid oxidase and i.-amino acid transamiaase ia the animal body (156), the D-form of methionine is as equally nutritive as the L-form, so that DL-methionine which is iaexpensively produced by chemical synthesis is primarily used as a feed supplement. In the United States the methionine hydroxy analogue is partially used ia place of methionine. The consumption of L-lysiae has iacreased ia recent years. The world consumption tripled from 35,000 t ia 1982 to 100,000 t ia 1987 (214). Current world consumption of L-tryptophan and i.-threonine are several tens to hundreds of tons. The demand for L-phenylalanine as the raw material for the synthesis of aspartame has been increasing markedly. 

Veterinary Applications. Another use for antibiotics is for veterinary appHcations and for animal feed supplements to promote growth in Hvestock (see Feeds and feed additives). Feed antibiotics used in the United States far surpass all other agricultural appHcations in terms of kilogram quantities used and approach quantities used in human medicines (25). In 1980 the USA feed antibiotic usage was estimated to be between five and six million kg. The U.S. Council of Agricultural Science and Technology estimates that feed additives save the U.S. consumer approximately 3500 million per year in meat prices, and antibiotic use accounts for most of this. 

In 1956 selenium was identified (123) as an essential micronutrient iu nutrition. In conjunction with vitamin E, selenium is effective iu the prevention of muscular dystrophy iu animals. Sodium selenite is adrninistered to prevent exudative diathesis iu chicks, a condition iu which fluid leaks out of the tissues white muscle disease iu sheep and infertility iu ewes (see Eeed ADDITIVES). Selenium lessens the iacidence of pneumonia iu lambs and of premature, weak, and stillborn calves controls hepatosis dietetica iu pigs and decreases muscular inflammation iu horses. White muscle disease, widespread iu sheep and cattle of the selenium-deficient areas of New Zealand and the United States, is insignificant iu high selenium soil areas. The supplementation of animal feeds with selenium was approved by the U.S. EDA iu 1974 (see Eeed additives). Much of selenium s metaboHc activity results from its involvement iu the selenoproteia enzyme, glutathione peroxidase. 

Iodized Salt. Iodized table salt has been used to provide supplemental iodine to the U.S. population since 1924, when producers, in cooperation with the Michigan State Medical Society (24), began a voluntary program of salt iodization in Michigan that ultimately led to the elimination of iodine deficiency in the United States. More than 50% of the table salt sold in the United States is iodized. Potassium iodide in table salt at levels of 0.006% to 0.01% KI is one of two sources of iodine for food-grade salt approved by the U.S. Food and Dmg Administration. The other, cuprous iodide, is not used by U.S. salt producers. Iodine may be added to a food so that the daily intake does not exceed 225 p.g for adults and children over four years of age. Potassium iodide is unstable under conditions of extreme moisture and temperature, particularly in an acid environment. Sodium carbonate or sodium bicarbonate is added to increase alkalinity, and sodium thiosulfate or dextrose is added to stabilize potassium iodide. Without a stabilizer, potassium iodide is oxidized to iodine and lost by volatilization from the product. Potassium iodate, far more stable than potassium iodide, is widely used in other parts of the world, but is not approved for use in the United States. 

Stevioside and rebaudioside A are diterpene glycosides. The sweetness is tainted with a bitter and undesirable aftertaste. The time—intensity profile is characteristic of naturally occurring sweeteners slow onset but lingering. The aglycone moiety, steviol [471 -80-7] (10), which is the principal metaboHte, has been reported to be mutagenic (79). Wide use of stevia ia Japan for over 20 years did not produce any known deleterious side effects. However, because no food additive petition has been presented to the FDA, stevioside and related materials caimot be used ia the United States. An import alert against stevia was issued by the FDA ia 1991. In 1995, however, the FDA revised this import alert to allow the importation and use of stevia as a diet supplement (80), but not as a sweetener or an ingredient for foods. Several comprehensive reviews of stevia are available (81,82). 

Vitamins are sold for direct appHcation to foods and animal feeds. In addition, they are further processed into nutritional supplements. This last market is particularly significant in the United States. In many other countries, vitamins are regulated as dmgs, leading to a much lower supplement usage. 

The primary uses of pyridoxine hydrochloride are in multivitamin supplement tablets and for fortification of human food and animal feed, especially for poultry and pigs. Most breakfast cereals and infant formulas in the United States are supplemented. Lesser amounts are used therapeutically to correct deficiencies or to treat specific disorders. Pyridoxine hydrochloride has been used experimentally to treat a variety of conditions with varying degrees of effectiveness (4,23). Pyridoxine hydrochloride is readily incorporated into premixes and foods. 

Thiamine requirements vary and, with a lack of significant storage capabiHty, a constant intake is needed or deficiency can occur relatively quickly. Human recommended daily allowances (RDAs) in the United States ate based on calorie intake at the level of 0.50 mg/4184 kj (1000 kcal) for healthy individuals (Table 2). As Httle as 0.15—0.20 mg/4184 kJ will prevent deficiency signs but 0.35—0.40 mg/4184 kJ are requited to maintain near normal urinary excretion levels and associated enzyme activities. Pregnant and lactating women requite higher levels of supplementation. Other countries have set different recommended levels (1,37,38). 

Cmde oil containing about 30% asphalt can be refined completely in an atmospheric unit to an asphalt product. However, most cmde oil cannot be distilled satisfactorily to an asphalt product at atmospheric pressure because of the presence of substantial proportions of high boiling gas oil fractions. Thus, as a supplement to the atmospheric process, a second fractionating tower (a vacuum tower) is added (Fig. 1). 

British and U.S. courts began developing case law to protect trademarks against infringement in the early 1800s. In 1883, the United Kingdom adopted a statute that provided for registration of fancy words as trademarks. The United States enacted its first federal trademark statute in 1870, but the statute was declared unconstitutional in 1879. Subsequent federal trademark statutes were adopted in the United States in 1881, 1905, and 1920 the present comprehensive statute, known as the Lanham Act, was enacted in 1946. The Lanham Act was substantially revised for the first time in 1988 by the Trademark Law Revision Act of 1988. The 1988 act, which became effective on November 16, 1989, both modified and supplemented the earHer statute. 

United States Trademark Association, The State Trademark Statutes, New York, 1989. A looseleaf book (with supplements) containing the trademark laws of the 50 states. 

In the procedure for the surface test (313), the vims is grown in a monolayer of baby hamster kidney cells and incubated in Eagles medium supplemented with tryptose phosphate broth and calf semm. After separation of the vims from the cells by sonification and centrifugation, amounts of the suspension containing 3 x 10 plaque-forrning units are dried on coversHps. The inoculated coversHps are placed in 5 ml of the disinfectant for 1, 5, or 10 min, then rinsed, sonicated, and assayed. 

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