Growth inhibition

BAS 111 l-Phenoxy-3-(lH-l,2,4-tria2ole-l-yl)-4-hydroxy-5,5-dimethylhexane [9003-11-6] (BAS 111) (46) is a triazole that has plant growth inhibiting properties. It exerts its influence by inhibiting the production of gibbereUic acid in plants this has been demonstrated in canola (31,37). 

Cell Division Inhibitors. The most common mode of action of soil-appHed herbicides is growth inhibition, primarily through dkect or indkect interference with cell division (163). Such growth inhibitory activity is the basis for most pre- or post-emergent herbicides intended to control germinating weed seeds. In germinating seeds, cell division occurs in the meristems of the root and the shoot. Meristematic cells go through a cycle... 

Amino acids essential for young rats (98) and fishes (99) have been reviewed. Rats preferably eat a diet with sufficient amounts of essential amino acids rather than one that is deficient (100). Each essential amino acid, consumed in self-selection, has been reviewed (101). A protein diet with an excess of essential amino acids has been described as a poor protein diet from investigations that showed remarkable growth inhibition and occurrence of fatty fiver disease in rats (102). This is called amino acid imbalance (103). 

Some related antibacteiials are also included with the sulfonamides. The azo dye, Piontosil (3) is metabolized to sulfanilamide in and was the piogenitoi of the sulfa dmgs. Also, the antibacteiial sulfones, eg, dapsone (4), are believed to act in a similai fashion on enzymes involved with synthesis of fohc acid, leading to bacterial growth inhibition. 

Sundower Seed. Compared to the FAO/WHO/UNU recommendations for essential amino acids, sunflower proteins are low in lysine, leucine, and threonine for 2 to 5-year-olds but meet all the requirements for adults (see Table 3). There are no principal antinutritional factors known to exist in raw sunflower seed (35). However, moist heat treatment increases the growth rate of rats, thereby suggesting the presence of heat-sensitive material responsible for growth inhibitions in raw meal (72). Oxidation of chlorogenic acid may involve reaction with the S-amino group of lysine, thus further reducing the amount of available lysine. 

In summary, dispersants are effective for particle dispersion and crystal growth inhibition, but do not normally have surface-active properties such as oil emulsification. Chelants and antiprecipitants frequently inhibit crystal growth better than dispersants, but are ineffective for particle dispersion. Flocculants are effective for aggregating particles, the opposite function of a dispersant. 

Material Function Typical dosage, ppm Ratio of cation to material Oil emulsification Kaolin dispersing CaCO growth inhibition... 

Microbiol Stability. Microbial growth is hindered by reducing water activity and adding preservatives. An overview is available (30). Reduction in water activity is typically obtained by including approximately 50% of a polyalcohol such as sorbitol or glycerol. Furthermore, 20% of a salt like NaCl has a pronounced growth inhibiting effect. 

When reacted with dimethyl acetylenedicarboxylate, the amines produced ben-zotriazolylaminobutendioates 188 accompanied by A-benzotriazolyl substituted 2-pyridones only in the case of 5-amino-2-methyl-2//-benzotriazole, the triazolo-9,10-dihydrobenzo[d]azepine and an unusual cyclization product, triazolo-2-oxindole (convertible into 2-methyltriazolo[4,5-/]carbostyril-9-carboxylate) were formed. The quinolones 189 were aromatized to chloroesters 190 these in turn were hydrolyzed to chloroacids 191 and decarboxylated to 9-chlorotriazolo[4, 5-/]quinolines 192 (Scheme 58) (93H259). The chlorine atom could be replaced with 17 various secondary amines to give the corresponding 9-aminoalkyl(aryl) derivatives 193, some of which exhibit both cell selectivity and tumor growth inhibition activity at concentrations between 10 and 10 " M (95FA47). 

Wachstum, w, growth increase accretion, wachstum-fordemd, a. growth-promoting,. hemmend, a. growth-checking, growth-inhibiting. 

Foam in the bioreactor is troublesome it can reduce the oxygen transfer rate (OTR). Antifoam is use to prevent foam formation. However, excess antifoam may cause growth inhibition in the course of fermentation. The simplest device is known as a foam breaker, which is mounted on the stirrer shaft located on the surface of liquid. It is a flat blade. 

Essential oils are known to have detrimental effects on plants. The inhibitory components have not been identified, but both alde-hydic (benzol-, citrol-, cinnamal-aldehyde) and phenolic (thymol, carvacol, apiol, safrol) constituents are suspected. Muller et al. (104) demonstrated that volatile toxic materials localized in the leaves of Salvia leucophylla, Salvia apiana, and Arthemisia californica inhibited the root growth of cucumber and oat seedlings. They speculated that in the field, toxic substances from the leaves of these plants might be deposited in dew droplets on adjacent annual plants. In a subsequent paper, Muller and Muller (105) reported that the leaves of S. leucophylla contained several volatile terpenes, and growth inhibition was attributed to camphor and cineole. 

Coumarin, the lactone of o-hydroxycinnamic acid, and some of its derivatives have been isolated from many plant species 31). Thimann and Bonner 141) attributed the growth-inhibiting effects of coumarin to its action on enzyme sulfhydryl groups. Inhibitory effects of coumarin on Avena coleoptiles and pea stem sections could be overcome by 2,3-dimercaptopropanol (BAL). Coumarin has also been reported to disrupt mitosis 29,30). 

Figure 2. Structural formulas of some lactones isolated from plants which have a growth-inhibiting action...

Ailanthus altissima (tree of heaven) grows in pure stands, hence, secretion of a toxic principle is implied. Mergen (98) prepared aqueous extracts of the foliage and found growth inhibition produced in 45 of 46 species of test plants. 

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