Inhibited radicle growth

Compounds 58 and 59 showed phytotoxic effects when tested against seedlings of A. hypochondriacus using a Petri dish bioassay. Compounds 58 [IC50 = 6.57 xM] and 59 [IC50 = 3.86 xM] inhibited radicle growth of this species with a similar potency to 2,2—dichlorophenoxyacetic acid [2,4-D IC50 = 18 xM], which was used as a positive control. 

Nicotine (43) inhibits radicle growth in Lepidium and is toxic to Lemna (Wink, 1993). It is a useful insecticide and probably serves as a defensive compound in the plant (Wink, 1993). Some coadapted insects, such as the tobacco horn-worm, Manduca sexta, are highly resistant to the effects of... 

Hyoscyamine (18) is produced in the roots of Datura (Solanaceae), but not in the leaves. This is the most common alkaloid in solanaceous plants (Cordell, 1978). This alkaloid inhibits germination of certain seeds, inhibits radicle growth in Linum, and is toxic to Lemna (Wink, 1993). Hyoscyamine, usually obtained from Hyoscyamus species) is a powerful anticholinergic drug. Hyoscyamine is a feeding deterrent for several insects (Wink, 1993). 

Williams et al., 1987). Lobeline is a feeding deterrent for several insects. The alkaloid is toxic to Lemna and inhibits radicle growth of Lepidium (Wink, 1993). 

Table III. Effect of culture broth (2 ml/petri dish) and dichloromethane extract of culture broth (0.2 mg/petri dish) on cress radicle growth, as related to presence of cyclohex-imide. Data are for all isolates tested in liquid culture whose broth inhibited cress radicle growth to 50% of controls...

Reduced germination and inhibition of radicle growth Causes morphological deformities in germinating medic seedlings by interfering with cell division and early growth of meristems... 

A. sedillense aqueous extract only inhibited the radicle growth of bean 25% but tomato radicle growth 60%. In bean root, A. sedillense aqueous extract increased the expression of 16 proteins (Table 14.1, Figs. 14.1A and 14.1B). In treated-tomato roots, 14 proteins were modified. Twelve proteins increased (1-8, 10-11, 13-14), one was detected only in this treatment (9), and another one was repressed (12) (Table 14.1 and Figs. 14.1C and 14.1D). 

Aqueous extract of L. camara inhibited 41% and 81% bean and tomato radicle growth, respectively. However, this treatment modified a similar number of proteins in both plants. In treated-bean roots, the expression of 15 proteins was modified 6 proteins were increased (2, 8-12), and 8 were decreased (3-7 13-15) (Table 14.2, Figs. 14.2A and 14.2B). In tomato treated-roots, 11 proteins were modified six proteins were increased (1-6), and 5 were decreased (7-11) (Table 14.2, Figs. 14.2B and 14.2D). 

Aqueous extract of A. sedillense inhibited the radicle growth of bean only 25% and tomato radicle growth 60%. In spite of the difference of effects on root growth, both plants showed a similar number of modified proteins (16 and 14, respectively). In both target plants, modified proteins were increased, but this effect is more obvious in bean root. 

Hyoscyamine Inhibition of germination, radicle growth in Linum — 245... 

---