Saccharomyces cerevisiae growth inhibition

Thomas, K.C., Hynes, S.H., and Ingledew, W.M. 2002. Influence of medium buffering capacity on inhibition of Saccharomyces cerevisiae growth by acetic and lactic acids. Applied and Environmental Microbiology 68 1616-1623. 

Empirical C18H39NO3 Properties Wh. powd. m.w. 317.51 Toxicology Potentially harmful by inh., ing. potential eye/skin irritant Hazardous Decomp. Prods. CO, CO2 Uses Preservative, antimicrobial in deodorants, skin care antimicrobial in acne preps. regulatory llpid, antibacterial barrier in the skin anti-inflammatory induction of apoptotic cell death In human cancer cells inhibits cell growth of Saccharomyces cerevisiae by inhibiting tryptophan import precursor of ceramides... 

Dining batch fermentation of Saccharomyces cerevisiae, other influential parameters can adversely influence the specific rate of growth, and inhibition can be caused either by... 

Example 12.7 Develop a model for the anaerobic batch fermentation of glucose to ethanol and coproduct CO2 using Saccharomyces cerevisiae. The starting mixture contains 10% glucose. The inoculum is 0.0005 w/w. Product inhibition stops cell growth at 14% ethanol. Assume ka = 0 but include the cannibalization of cellular material beginning when the substrate is completely consumed. 

Saccharomyces cerevisiae i i27-8b strain. The latter compound also inhibited the growth of Candida albicans 258 strains. 

Acetylenic isobutylamides and polyacetylenes occurring in Echinacea have been shown to inhibit the growth of yeast strains of Saccharomyces cerevisiae, Candida shehata, Candida kefyr, Candida albicans, Candida steatulytica, and Candida tropicalis. This growth inhibition occurred to a greater extent under ultraviolet irradiation than without it. There are other compounds in Echinacea that are suspected to be phototoxic to microbes, but this has yet to be demonstrated (16). 

Abbott, D. A. and Ingledew, W.M. 2004. Buffering capacity of whole corn mash alters concentrations of organic acids required to inhibit growth of Saccharomyces cerevisiae and ethanol production. Biotechnology Letters 26 1313-1316. 

Pearce, A.K., Booth, I.R., and Brown, A.J.P. 2001. Genetic manipulation of 6-phos-phofructo-l-kinase and fructose 2,6-bisphosphate levels affects the extent to which benzoic acid inhibits the growth of Saccharomyces cerevisiae. Microbiology 147 403-410. 

Fishbein, J.D., Dobrowsky, R.T., Bielawska, A., Garrett, S., and Hannun, Y.A. Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae. J Biol Chem, 268, 1993, 9255-9261. 

Similarly to their antibacterial activity, resorcinolic lipids exhibit fungistatic properties. However, experiments indicate that resorcinolic lipids inhibit the growth of Trichophyton mentagrophytes and Saccharomyces cerevisiae to a lower degree than observed for bacteria. No activity was shown against Candida albicans and Asperigullus niger [256]. The occurrence of 5-n-(heptadec-12-enyl) and 5-n-... 

Finally, lycorine inhibited the growth of rho+, mit and rho strains of Saccharomyces cerevisiae, while rho0 strains (devoid of mitochondrial DNA) were resistant to high concentrations of the alkaloid. Total protein synthesis and mitochondrial protein synthesis are only slightly inhibited by lycorine. It had, however, an inhibitory effect on DNA and RNA [172],... 

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