Disease control disease

Phenylpyruvic acid can cause mental retardation m infants who are deficient m the enzymes necessary to convert l phenylalanine to l tyrosine This disorder is called phenylketonuria, or PKU disease PKU disease can be detected by a simple test rou tmely administered to newborns It cannot be cured but is controlled by restricting the dietary intake of l phenylalanine In practice this means avoiding foods such as meat that are rich m l phenylalanine... 

Aquatic animals are susceptible to a variety of diseases including those caused by viruses, bacteria, fungi, and parasites. A range of chemicals and vacciaes has been developed for treating the known diseases, although some conditions have resisted all control attempts to date and severe restrictions on the use of therapeutants ia some nations has impaired that abiUty of aquaculturists to control disease outbreaks. The United States is a good example of a nation ia which the variety of treatment chemicals is limited (Table 6). 

Centers for Disease Control, Morbid. Mortal Weekly Rep. 45, 29 (1996). 

NIOSH Alert, Requestfor Assistance in Preventing Adverse Health Effectsfrom Exposure to Dimethjlformamide (DMF), DHHS (NIOSH) PubUcation No. 90-105, Center for Disease Control, U.S. Dept, of Health and Human Services, Washington, D.C., Sept. 1990. 

Mechanism of Action. The mechanisms by which antibiotic adrninistration at subtherapeutic levels enhance growth rate and efficiency of gain in growing animals have not been clarified. Possible modes of action include disease control, nutrient sparing, and metaboHc effects. There is extensive evidence that the principal benefit from subtherapeutic use of antibiotics results from the control of harmfiil microorganisms. 

The alimentary symptoms may be overshadowed by neuromuscular dysfunction, accompanied by signs of motor weakness that may progress to paralysis of the exterior muscles or the wrist (wrist drop), and less often, of the ankles (foot drop). Encephalopathy, the most serious result of lead poisoning, frequendy occurs in children as a result of pica, ie, ingestion of inorganic lead compounds in paint chips this rarely occurs in adults. Nephropathy has also been associated with chronic lead poisoning (147). The toxic effects of lead may be most pronounced on the developing fetus. Consequendy, women must be particulady cautious of lead exposure (148). The U.S. Center for Disease Control recommends a blood level of less than 10 p.m per 100 mL for children. 

R. J. Lewis, Sr. and R. L. Tatkin, eds.. Registry of Toxic Effects of Chemical Substances, 8th ed.. National Institute for Occupational Safety and Health, Pubhc Health Service Center for Disease Control, U.S. Government Printing Office, Washington, D.C., 1979. 

Biology and Control ofMedes aegypti, Hector Topics No. 4 and Dengue Surveillance Survey No. 9, U.S. PubHc Health Service, Centers for Disease Control and Prevention, Adanta, Ga., 1979 and 1983. 

Chemical treatment of diseases is not common, because of legislative controls and costs caused by the difficulty of appHcation through the leaf canopy. Breeding of resistant varieties is the main weapon for disease control. Some diseases, chiefly ratoon stunting disease, are controlled by hot water treatment of cane (6,8). 

Vaccines are used in either the general population of children or adults or for special groups. Recommendations for vaccine usage are made by the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control. The Committee on Infectious Diseases of the American Academy of Pediatrics (Redbook Committee) also makes recommendations for infants through adolescents, and the American Academy of Family Physicians makes recommendations for adults. An excellent review of vaccine history, development, usage, and related regulatory issues is available (2). 

Gonorrhea. Gonorrhea, caused by Neisseriagonorrheae is the most commonly reported communicable disease in the United States. Approximately lO cases were reported to the Center for Disease Control (CDC) in 1979, but actual cases could be two to three times higher (99,100). In addition, an increasing number of strains are becoming resistant to penicillin, the antibiotic that is usually used to treat this disease. 

Mobidity and Mortality Weekly Report (MMWR) Vol. 44, RR 5, Centers for Disease Control, Adanta, Ga., June 1993. 

Eegistry of Toxic Effects of Chemical Substances, NIOSH, U.S. Dept, of Health and Pubhc Services, Pubhc Health Service, Centers for Disease Control, Cincinnati, Ohio, (CCINFO disc as format), 1995. 

Suggested Health and Safety Guidelines for Public Spas and Hot Tubs, U.S. Department of Health and Human Services PubHcation No. 99-960, Centers for Disease Control, Atianta, Ga., 1985. 

Malaria affects an estimated 270 million people and causes 2—3 million deaths annually, approximately one million of which occur in children under the age of five. While primarily an affliction of the tropics and subtropics, it has occurred as far north as the Arctic Circle. The disease essentially has been eradicated in most temperate-zone countries, but some 1100 cases of malaria in U.S. citizens returning from abroad were reported to the Centers for Disease Control during 1990. Malaria is seen today in Southeast Asia, Africa, and Central and South America. It is on the increase in Afghanistan, Brazil, China, India, Mexico, the Philippines, Sri Lanka, Thailand, and Vietnam. Escalation of the disease is because of the discontinued use of the insecticide DDT which effectively kills mosquito larvae, but has been found to be toxic to Hvestock and wildlife. Also, chloroquine (6), a reUable dmg for the prophylaxis and treatment of falcipamm malaria, is ineffective in many parts of the world because of the spread of dmg-resistant strains. 

Intensive or extensive culture of aquatic animals requires chemicals that control disease, enhance the growth of cultured species, reduce handling trauma to organisms, improve water quality, disinfect water, and control aquatic vegetation, predaceous insects, or other nuisance organisms. The aquacultural chemical need for various species have been described for rainbow trout, Oncorhjnchus mjkiss (1) Adantic and Pacific salmon, Salmo and Oncorhjnchus sp. (2) channel catfish, Ictaluruspunctatus (3) striped bass, Morone saxatilis (4) milkfish, Chanos chanos (5) moUusks (6) penaeid (Penaeus sp.) shrimp (7) and a variety of other marine species (8). 

Gainesville (Florida) Sun, quoting Pierre Payment, Institute Arm an d-Frappier (Montreal), Judy Lew and Christine Moe at Centers for Disease Control, Adanta, and Phillip Berger, EPA, 5A, Dec. 8, 1990. 

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