The Project Database

Within a contract, the partitioning into elements should reflect well-understood areas of competence and responsibility within the organisation. 

The partitioning should be chosen so that the interfaces are minimised and, where possible, in accordance with industry interface standards. This applies to information exchange interfaces as well as physical interfaces, such as voltage levels, flange sizes, standard packaging (container) sizes, etc. 

Examine the use of Commercial-Off-The-Shelf (COTS) elements at the flrst opportunity in the development of the PBS, as there would have to be a robust cost-effectiveness argument (taking development risk into account) for choosing anything else. 

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Validation of computer aided review tools, which may be used by in-house or regulatory reviewers to explore the project database on a read-only basis, should address both the system and project-specific aspects. 

Consistency of the viewed data with the project database... 

For submission of the sampling protocols by the participants, a server has been prepared and established at the ICTP network, providing a web-based interface to the project database. Also all necessary information for the participants was offered via this system. The system was found to work in a satisfactory and robust manner, also as an example for possible arrangements for future exercises. In this frame ... 

The design support software tools employed in the case study are of a completely different nature. They include commercial as well as legacy tools. Examples are Microsoft Excel, various process simulators such as Polymers Plus from Aspen Technology, gPROMS from PSE, MOREX, BEMFlow and BEMView from Institut filr Kunststoffverarbeitung at RWTH Aachen University, the project database Comos PT from innotec, the document manage-... 

Since 2007, monitoring data available through NORMAN project participants, NORMAN contact points, reference laboratories and other network members have started to be entered in the database. Whenever possible, the existing databases are uploaded directly into the project database via specific software interfaces. For collection of the other data, simple pre-programmed Excel sheets matching the structure of the database are used. 

Figure 7.2 Principle of the project database. The register database comprises three cross-tables Bs, , Man, and Man 2. All serum TSH, T3, and T4 results are imported into Bs, where primarily TSH and, in case of abnormal value, T3 and T4 are evaluated. Cases of biochemical overt hyper- or hypothyroidism are copied to cross-table Man, which consists of two subsections known cases (already registered in the database) and possible new case (without any prior database registration). All possible new cases are manually cross-checked (see text). All new cases are copied to cross-table Man 2 and after that registered as known cases. Data taken from Pedersen et al., (2002) with permission from Elsevier.

All sub-processes of the development process, beginning with the perception of deficiencies, require the analysis of process data. The data characterizes the system s performance and behaviour. This is necessary to parametrize the simulation model and build a credible basis for comparing the model s behaviour and reality. A common database maintained by both modellers and managers allows linking necessary and available information. A lack of data may lead to uncertainty, more complexity, and a loss in accuracy. Uncertainty is reflected e.g. by stochasticity at variables which in turn may lead to a larger number of simulation experiments and more volatile performance measures. On the other hand, the information collected in the project database needs to be relevant for the project. Otherwise, a flood of data to be evaluated and analysed hinders an efficient development process as it is time and resource consuming. 

When producing any risk assessments, which include a significant contribution from the low frequency high consequence type events for which there is little or no historical experience, it is necessary to make predictions on the likelihood and consequences of the specific outcomes following the occurrence of a hazardous event. This process inevitably leads to the requirement for judgement-based assumptions. The accuracy of the overall risk results is therefore sensitive to the accuracy of the assumptions made. All assumptions made within the model are justified and recorded within the project database and associated documentation. 

Which documents present in the project database, if any, can be modified from site (Perhaps only to raise them to as-built status) ... 

This presentation will not attempt to present all these projects, but instead focus on the ongoing network activities and the available sources for further information through the Commission s information services, with the CORDIS database being the prime source of information (see details at the end of the paper). 

Factual databases mainly contain alphanumeric data on chemical compounds. In contrast to bibliographic databases, factual databases directly describe the objects primary data on chemical compounds) and provide the required information on them. Factual databases can be divided into numeric databases, metadatabases, research project databases, and catalogs of chemical compounds. 

Nuclear Magnetic Resonance Spectroscopy. Bmker s database, designed for use with its spectrophotometers, contains 20,000 C-nmr and H-nmr, as weU as a combined nmr-ms database (66). Sadder Laboratories markets a PC-based system that can search its coUection of 30,000 C-nmr spectra by substmcture as weU as by peak assignments and by fiiU spectmm (64). Other databases include one by Varian and a CD-ROM system containing polymer spectra produced by Tsukuba University, Japan. CSEARCH, a system developed at the University of Vieima by Robien, searches a database of almost 16,000 C-nmr. Molecular Design Limited (MDL) has adapted the Robien database to be searched in the MACCS and ISIS graphical display and search environment (63). Projects are under way to link the MDL system with the Sadder Hbrary and its unique search capabiHties. 

GORE. The CORE Electronic Chemistry Library is a joint project of Cornell University, OCLC (On-line Computer Library Center), Bell Communications Research (Bellcore), and the American Chemical Society. The CORE database will contain the full text of American Chemical Society Journals from 1980, associated information from Chemical Abstracts Service, and selected reference texts. It will provide machine-readable text that can be searched and displayed, graphical representations of equations and figures, and full-page document images. The project will examine the performance obtained by the use of a traditional printed index as compared with a hypertext system (SUPERBOOK) and a document retrieval system (Pixlook) (6,116). 

In this chapter, we will discuss the present status of CHIRBASE and describe the various ways in which two (2D) or three-dimensional (3D) chemical structure queries can be built and submitted to the searching system. In particular, the ability of this information system to locate and display neighboring compounds in which specified molecular fragments or partial structures are attached is one of the most important features because this is precisely the type of query that chemists are inclined to express and interpret the answers. Another aspect of the project has been concerned with the interdisciplinary use of CHIRBASE. We have attempted to produce a series of interactive tools that are designed to help the specialists or novices from different fields who have no particular expertise in chiral chromatography or in searching a chemical database. 

If some fields may be empty in the sublevels, all the fields in the main level are required for each entry. A new chiral separation record can be added in CHIRBASE solely if the authors correctly identify both sample and CSP. Since the beginning of the project, our policy has been to contact the authors of all publications containing incomplete, ambiguous or inconsistent data and to ask for additional information. Providing the separations with unique case numbers helps us considerably in this essential task, and also facilitates avoiding redundancies in the database. When chiral separations are reported for the second time in a new publication with exactly the same chromatographic conditions, this is stated in a footnote added in the field comments . In this field, miscellaneous information that cannot appear elsewhere are listed (detection limit, description of a reported chromatogram, racemization study, mobile phase limitations, etc.). 

We are providing these tools to enter data into the database and trying to convince chemists that it is in their own interest to participate with their data for use by the community. This is a very important aspect of the project, as an increasing number of results obtained as a result of analytical chiral methods are published without adequate description of these tools. 

With the onset of genomic biology, there are now many sequences derived from genome sequencing projects that are too divergent to be considered species variants of known peptidases. Of the 54,124 sequences in the MEROPS database only 18,741 (34.6%) have been assigned to an identifier. 

The DIPPR databases were developed in the United States by the Design Institute for Physical Properties of the American Institute of Chemical Engineers. The DIPPR projects are aimed at providing evaluated process design data for the design of chemical processes and equipment (www.aiche.org/dippr/projects.htm). The Project 801 has been made available to university departments see Rowley et al. (2004) and http.//dippr.byu. edu/description/htm. 

Information about the prevalence of other oxygenates in the environment is limited. However, there is evidence that other oxygenates may be found at sites contaminated with MTBE non-MTBE oxygenates were identified as a contaminant at 29 of the projects in U.S. EPA s database. In addition, several surveys have assessed the nature and extent of contamination with other oxygenates within the United States.11-14 15... 

Of the projects in the database, four completed projects using pump-and-treat provided performance data for initial and final MTBE concentrations. Median concentrations were 27,000 pg/L for before treatment and <1 pg/L for after treatment. The median project duration for these projects was 14 months. Note that these treatment performance figures are based on the data provided by project managers and others in the source materials used to prepare the treatment profiles website. 

Within the project we also evaluated alternative methods as tools to obtain information on the toxicological and physicochemical profile of the pollutants. In this paragraph, an example of the application of QSARs models is reported a comparison is done between predicted values from different models or between QSARs evaluation and experimental values from internationally recognized databases. 

Inventory (NFI) site and will thus help link the newly acquired data with that database. Partly because of the pilot aspect of the project and partly because of all the partners involved (7 different departments/ agencies), a large number (19) of samples from various soil horizons was collected at each site (Fig. 2). Such... 

It is the responsibility of the Central Safety Testing Lab staff to scan test results into the database and to serve as database administrators. 2. It is the responsibility of the Product Safety and Product Regulatory Programs to develop MSDSs and Workplace Precaution Statements. 3. It is the responsibility of the project/process leader to ensure the Survey Sheets have been completed, and that MSDSs or workplace precaution statements have been requested. ... 

For more information about proposed CCS projects refer to CERA (2007), IEA (2006), or the IEA GHG R D Programme (www.ieagreen.org.uk) general C02 projects database is also available at www.co2captureandstorage.info. 

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