Genomics biologicals

With the onset of genomic biology, there are now many sequences derived from genome sequencing projects that are too divergent to be considered species variants of known peptidases. Of the 54,124 sequences in the MEROPS database only 18,741 (34.6%) have been assigned to an identifier. 

Peruski, L. F. Peruski, A. H. Rapid diagnostic assays in the genomic biology era Detection and identification of infectious disease and biological weapon agents. BioTechniques 2003, 35, 840-846. 

Joost, P. and Methner, A. (2002) Phylogenic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome Biology, 3, 63.1-63.16, http //genomebiology.eom/2002/3/ll/ research/0063. 

Pan W, Lin J, Le G. 2002. How many replicates of arrays are required to detect gene expression changes in microarray experiments A mixture model approach. Genome Biology 3(5) research0022.1. 

Cui, X. and Churchill, G.A. (2003) Statistical tests for differential expression in cDNA microarray experiments. Genome Biology, 4, 210. 

Minireview. Genome Biology 2 1018.1-1018.5 Harris JR, Scheffler D (2002) routine preparation of air-dried negatively stained and unstained specimens on holey carbon support films A review of applications. Micron 33 461-480... 

Hoffmann, K.F. and Dunne, D.W. (2003) Characterization of the Schistosoma transcriptome opens up the world of helminth genomics. Genome Biology 5, 203. 

Stephen W. Scherer Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario, Canada... 

Genomic biology takes a holistic approach to molecular biology and volution by studying the complete genome, its genes, and its protein expression patterns. 

Haab BB, Dunham MJ, Brown PO, Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions, Genome Biology, 2 1-13, 2001. 

Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., and Speleman, F. (2002). Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biology, 3, 0034.1-0034.11. 

Andersen MR, Lehmann L, Nielsen J (2009) Systemic analysis of the response of Aspergillus niger to ambient pH. Genome Biology 10(5) R47... 

J. Bard, S. Y. Rhee, and M. Ashbumer. 2005. An ontology for cell types, Genome Biology 6 R21. 

K. Eilbeck, S. E. Lewis, C. J. Mungall, M. Yandell, L. Stein, R. Durbin, and M. Ashbumer. 2005. The Sequence Ontology a tool for the unification of genome annotations, Genome Biology, 6 R44. 

Pace, H.C. and Brenner, C. 2001. The nitrilase superfamily Classification, structure and function. Genome Biology, 2 1-9. 

Scholl, T., Ponath, P.D., and Strominger, J.L., A factor that regulates the class II major histocompatibility complex gene DPA is a member of a subfamily of zinc finger proteins that includes a Drosophila developmental control protein, Mol. Cell. Biol. 14, 8438-8450, 1994 Kaczynski, J., Cook, T., and Urrutia, R., Spl- and Kriippel-like transcription factors. Genome Biology 4, article 206, 2003. 

D. L. Black. 2000. Protein diversity from alternative splicing A challenge for bioinformatics and post-genome biology Cell 103 367-370. (PuhMed)... 

Werck-Reichhart D and Eeyereisen R (2000) Cytochromes P450 A success story. Genome Biology 1 Epub December 8, 2000. 

Willecke K, Eiberger J, Degen J, etal. (2002) Structural and functional diversity of connexin genes in the mouse and human genome. Biological Chemistry 383 725-737. 

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