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Toxic Substances Control Act Test

Toxic Substances Control Act Test Submissions (TSCATS)... [Pg.310]

TSCATS toxic substances control act test submissions... [Pg.603]

TSCATS Toxic Substances Control Act Test Submissions 4,200 submissions on 2,228 substances ENVIRONMENTAL PROTECTION AGENCY Unpublished health and safety studies submitted to the EPA. Provides a mechanism for ordering microfiche copies of studies... [Pg.27]

EPA. 2001k. Toxic substances control act. Testing consent order. U.S. Environmental Protection Agency. Code of Federal Regulations. 40 CFR 799.5000. http //ecffback.access.gpo.gov/otcgi/cfr. Decerrber 10, 2001. [Pg.262]

U.S. Environmental Protection Agency, Office of the Testing and Evaluation. Proposed Health Effects Test Standards for Toxic Substances Control Act Test Rules, 40 CFR, Part 772, Standards for Development of Test Data sub part D- Chronic Health Effects. Fed. Reg. 44(91) 27350, 1979. [Pg.55]

United States Environmental Protection Agency, Toxic Substances Control Act Test Guidelines, Health Effects Testing Guidelines, Subpart G, Neurotoxicity, Fed. Reg., Vol. 50, No. 188, pp. 39458-39470, 1985. [Pg.405]

Toxic Substances Control Act Test Submissions (TSCATS) Search. U.S.A. Syracuse Research Corporation. URL http // esc.syrres.com/efdb/TSCATS.htm. Use CAS numbers or chemical structures to search for chemicals use Study Type Search to narrow by acute or chronic, or even subacute toxicity alongside route of administration and organism. [Pg.65]

In the proposed Health Effects Test Standards for Toxic Substances Control Act Test Rules by the EPA (6), "chronic effects" was defined as ...disease processes which have a long latency period for development, result from long-term exposure, are long-term illnesses, or combinations of these factors." But ambiguity still exists for instance, how long is "long-term" The reason for the absence of a clear-cut definition for chronic toxicity is the complexity of events... [Pg.20]

Environmental Protection Agency, Proposed health effects test standards for Toxic Substances Control Act test rules Chronic health effects. Fed. Register 44 27356-27375 (May 9, 1979). [Pg.206]

U.S. EPA (Environmental Protection Agency). 1997. Toxic Substances Control Act test guide-hnes Final rule. 40 CFR. Part 799. [Pg.18]

To further compound the problem, test laboratories are also faced with PA s Proposed Health Effects Test Standards for Toxic Substances Control Act Test Rules and Proposed Good Laboratory Practice Standards for Health Effects. These proposed test standards were published separately for studies on chronic health effects (Federal Register, May 9, 1979, PP 2733 -27375) and for acute, subchronic, mutagenic, teratogenic, reproductive, and other health effects (Federal Register, July 26, 1979, PP ... [Pg.554]

EPA posts 8(e) reports it receives on its Web site, which are very useful for benchmarking, as well as for obtaining information about specific chemicals, though they are not very useful for guidance because they are merely industry interpretations. The EPA has also posted searchable summaries of 8(e) submissions in the Toxic Substances Control Act Test Submissions (TSCATS) database. [Pg.237]

US EPA. 2014. Toxic Substance Control Act Test Submissions, Version 2.0. Last Revision January 18, 2014. http //yosemite.epa.gov/oppts/epatscat8.nsf/ ReportSearch OpenForm (queried January 18,2014). [Pg.43]

All the PMBs are Hsted on the U.S. EPA s Toxic Substances Control Act NonConfidential Chemical Substances Inventory (Table 8). In the early to mid-1980s, pseudocumene, mesitylene, hemimellitene, and trimethylbenzene were coveted by TSCA Section 8(a) Preliminary Assessment Information Rule (PAIR) reporting requirements (22) and by TSCA Section 8(d) for health and safety data (23). Mesitylene is the subject of a test rule subacute oral toxicity and subchtonic oral toxicity in tats were underway in 1994 (24). The Safe Drinking Water Act (SDWA) allows monitoring for pseudocumene and mesitylene at the discretion of the State (25). Of the PMBs, only pseudocumene is subject to SARA Tide III section 313 annual release reporting (26). [Pg.509]

The Toxic Substances Control Act (TSCA) was enacted in 1976 to identify and control toxic chemical ha2ards to human health and the environment. One of the main provisions of TSCA was to estabUsh and maintain an inventory of all chemicals in commerce in the United States for the purpose of regulating any of the chemicals that might pose an unreasonable risk to human health or the environment. An initial inventory of chemicals was estabhshed by requiring companies to report to the United States Environmental Protection Agency (USEPA) all substances that were imported, manufactured, processed, distributed, or disposed of in the United States. Over 50,000 chemical substances were reported. PoUowing this initial inventory, introduction of all new chemical substances requires a Premanufacturing Notification (PMN) process. To be included in the PMN are the identity of the new chemical, the estimated first year and maximum production volume, manufacture and process information, a description of proposed use, potential release to the environment, possible human exposure to the new substance, and any health or environmental test data available at the time of submission. In the 10 years that TSCA has been in effect, the USEPA has received over 10,000 PMNs and up to 10% of the submissions each year are for dyes (382)... [Pg.388]

Another section of the EPA, the Office of Prevention, Pesticides, and Toxic Substances (OPPT), has recently updated and harmonized its testing guidelines for evaluating the developmental and reproductive effects of pesticides and industrial chemicals to include an assessment of endocrine disrupting properties. These guidelines will be used in future testing of pesticides under both the Toxic Substances Control Act (TSCA) and the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA). [Pg.24]

The Toxic Substances Control Act of 1976 was enacted by Congress to test, regulate, and screen all chemicals produced or imported into the U.S. Many thousands of chemicals and their compounds are developed each year with unknown toxic or dangerous characteristics. To prevent tragic consequences, TSCA requires that any chemical that reaches the consumer market be tested for possible toxic effects prior to commercial manufacture. Any chemical that poses health and... [Pg.26]

Fourteen formulations of chemical alternatives were submitted to EPA under confidentiality and they were assessed based on numerous human health and ecotoxicity endpoints in addition to bioaccumulation potential and environmental persistence. They were also screened for potential exposure to workers, users and the aquatic environment. Where data gaps existed, EPA experts used models and chemical analogs to estimate the hazard for a particular endpoint. The literature and test data reviews were published in the final report, Environmentally Preferable Options for Furniture Fire Safety Low Density Furniture Foam . In addition, each hazard endpoint was ranked with a concern level (High, Moderate or Low) based on the criteria used by the EPA s New Chemicals Program to rate the concern level of new chemicals submitted under the Toxic Substance Control Act (TSCA). As seen in Figure 8.2, where the hazard endpoint rankings are bold, the value is based on experimental data. Where the hazard endpoints are presented in italic font, the value is estimated based on models or chemical analogs. In this way, detailed hazard information was summarized and presented in a clear and concise format. [Pg.285]

TSCATS is an online index to unpublished, nonconfidential studies covering chemical testing results and adverse effects of chemicals on health and ecological systems. The studies are submitted by US industry to EPA under several sections of the Toxic Substance Control Act (TSCA). There are four types of documents in the database Section 4 chemical testing results, Section 8(d) health and safety studies, Section 8(e) substantial risk of injury to health or the environment notices, and voluntary documents submitted to EPA known as a For Your Information (FYI) notice. [Pg.310]

The only regulations found for organophosphate ester hydraulic fluids were for aryl phosphates. Two proposed rules for aryl phosphates address 1) exclusion from hazardous waste regulations and 2) additional testing, recordkeeping, and reporting under the Toxic Substances Control Act (TSCA). [Pg.331]

Most of the provisions of the Toxic Substances Control Act (TSCA) of 1976 (PL 94-469) rely in some way on risk assessment of chemicals. Under the reporting requirements of the statute, any manufacturer, processor, or distributor of a chemical for commercial purposes must inform the EPA immediately after discovering any information which "reasonably supports the conclusion" that a chemical substance or mixture "presents a substantial risk of injury to health or to the environment" unless the EPA Administrator has been adequately informed already. EPA is mandated to establish regulations for testing new or existing substances when it is determined that there is not enough health or environmental information, that testing is necessary to develop such information and that the chemical or mixture "may present an unreasonable risk of injury to health or the environment."... [Pg.91]

U.S. Environmental Protection Agency Toxic Substances Control Act (U.S. EPA TSCA) Chemical Inventory and Test Submission Data Base, 13 694 U.S. EPA Tier 2 specification, gasoline sulfur content, 10 54. See also Environmental Protection Agency (EPA)... [Pg.986]

The goal of the Toxic Substances Control Act (TSCA) is to provide authority to regulate chemical substances which present an unreasonable risk of injury to health or the environment. An important feature of TSCA requires the administrator of the Environmental Protection Agency (EPA) to examine such data on existing chemicals and, when it is insufficient, to direct industry to conduct tests. [Pg.67]

Environmental Protection Agency (EPA). (1979). Toxic Substances Control Act Premanufacture testing of new chemical substances. Guidance for premanufacture testing Discussion of policy issues, alternative approaches and tests methods. 44 FR 16240-16292. [Pg.524]

Besides, the list also includes the Toxic Substances Control Act in the USA (1976). the Canadian Environmental Protection Act (1994 ), the Chemical Substances Control Law in Japan (1973), and the Australian Chemicals Act (1989). These regulations, which also affect pigments, demand that all new products be registered. Various toxicological test results have to be presented, depending on the country. The discussed legal requirements are supplemented by many other more or less specific environmental acts, not only in the countries thus mentioned, but also in practically all other industrialized nations. [Pg.586]

Walker JD. 1990. Review of chemical fate testing conducted under section 4 of the toxic substances control act Chemicals, tests, and methods. J Bacteriol 13 78-90. [Pg.126]

More than 50,000 chemicals are currently listed in the Toxic Substance Control Act (TSCA) inventory, but physical-chemical properties are available for a relatively small percentage and biological endpoints for even less. The costs associated with thoroughly testing all chemicals are prohibitive, so models are needed to (1) predict the environmental effects of a new chemical, or (2) assess whether the chemical should be subject to a detailed testing regime (J ). Although models are available to... [Pg.148]


See other pages where Toxic Substances Control Act Test is mentioned: [Pg.603]    [Pg.505]    [Pg.603]    [Pg.505]    [Pg.386]    [Pg.301]    [Pg.250]    [Pg.6]    [Pg.67]    [Pg.123]    [Pg.154]    [Pg.161]    [Pg.171]    [Pg.510]    [Pg.301]   


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