Regulation chemical substance

The goal of the Toxic Substances Control Act (TSCA) is to provide authority to regulate chemical substances which present an unreasonable risk of injury to health or the environment. An important feature of TSCA requires the administrator of the Environmental Protection Agency (EPA) to examine such data on existing chemicals and, when it is insufficient, to direct industry to conduct tests. 

The RoHS procedure has now combined with European Union Registration, Evaluation, Authorisation and restriction of Chemicals (REACH), which is a new European Union Regulation (EC/2006/1907 of 18 December 2006). Four additional substances are listed that will be assessed as a priority, among these substances is hexabromocyclododecane, a brominated flame retardant widely used in expanded polystyrene for which no alternatives have been found so far. REACH addresses the production and use of chemical substances and their potential impacts on both human health and the environment it has been described as the most complex legislation in the Union s history and the most important in the last 20 years. It is the strictest law to date regulating chemical substances and will impact industries throughout the world. REACH entered into force in June 2007, with a phased implementation over the next decade. 

The manufacturer and/or importer of a new surfactant in Japan is required to register it beforehand under the Chemical Substances Control Law, a law to regulate chemical substances, and the Industrial Safety and Health Law, a law to protect the health of workers. A chemical substance that is not registered beforehand or is not exempt from the registration under the laws cannot be handled as a chemical substance in Japan. If you use such a substance without registration, you must not only pay a penalty but also recall your products in the worst case. This legislation is applicable to all chemical substances including surfactants. 

The Chemical Substances Control Law regulates chemical substances produced by chemical reaction excluding natural products. However, articles and substances regulated by other laws, such as the Food Sanitation Law in Japan and the Pharmaceutical Affairs Law, and exclusively used for the purposes covered by such laws, together with substances used for research and development, are also exempt from the Law. 

Under the TSCA, the EPA has authority to regulate chemical substances and mixtures via the following mechanisms ... 

Legislation regulating chemical substances falls into 4 basic categories ... 

The TSCA regulates chemical substances [2]. In the statute, the term chemical substance is defined as any organic or inorganic substance of a particular molecular identity, including (i) any combination of such substances occurring in whole or in part as a result of a chemical reaction or occurring in nature and (ii) any element or uncombined radical [3]. The EPA states TSCA defines chemical... 

Under the Toxic Substances Control Act (TSCA), numerous nomenclature issues have arisen over the years, some of which have been discussed in this book. There will undoubtedly be new nomenclature issues to be resolved, nanoparticles being a current case in point. Issues of the past have often arisen out of administrative and sometimes arbitrary naming conventions, but risks associated with chemical substances do not depend on how they are named. Nanoparticles present different issues in the sense that the Environmental Protection Agency (EPA) stated that the TSCA regulates chemical substances of a particular molecular identity, without regard to physical properties such as size and shape. Potential for significant risk due to nanoparticles clearly exists exactly due to those physical properties. Regulators and interpreters of the TSCA must address potential risks such substances may pose even if their non-nano counterparts do not, and even if their newness does not meet the current definition of substances with different molecular identities. 

TSCA has regulations concerning virtually all industrial chemicals and many chemicals that are not typically thought of as industrial chemicals, ranging from bulk commodity chemicals and PCBs to writing ink. Its provisions regulate chemical substances and mixtures, and both of these are defined terms that circumscribe the scope of TSCA and its regulations. 

The export notification requirement applies to a TSCA regulated chemical substance, and is not dependent on its end use. For those export notifications required because the EPA has restricted certain end uses, export notification must be given to EPA without regard to the actual intended use. For example, if the EPA restricts use under 5 to permit only the manufacture of an article, notification of export must stiU be given even if the foreign purchaser intends to make other use of the chemical substance. ... 

The exporter must submit a notification of export or of intent to export a regulated chemical substance or mixture. For purposes of 12(b), exporter is defined as the person who, as the principal party in interest in the export transaction, has the power and responsibihty for determining and controlling the sending of the chemical substance or mixture to a destination out of the customs territory of the United States. 

ChemCats (Chemical Catalogs Online) from CAS is a catalog database containing information on nearly 44,000,000 commercially available chemicals and their worldwide suppliers. ChemLisi (Regulated Chemicals Listing) from CAS is a collection of more than 248,000 regulated chemical substances. 

Toxic Substances Control Act. EPA regulates the manufacture, use, and exposure to ha2ardous or toxic chemicals under a number of laws. Eor the chemical industry, the law of prime concern is the Toxic Substance Control Act (TSCA) (10), which was passed by the U.S. Congress in 1976. The two main goals of TSCA are acquisition of sufficient information to identify and evaluate potential ha2ards from chemical substances, and regulation of the production, use, distribution, and disposal of these substances. 

The LD q for sodium bromide taken orally by rats is 3.5 g/kg body weight, and the TD q orally in rats is 720 mg/kg (8). RTECS Hsts data on reproductive effects in male and female rats. Sodium bromide is Hsted in the TSCA Inventory, the Canadian Domestic Substances Hst (DSL), the European Inventory of Existing Commercial Chemical Substances (EINECS), the Japanese Existing and New Chemical Substances (ENCS), and the Korean Existing Chemicals Hst (ECL). It is not regulated by the U.S. Department of Transportation. 

In the European Union, coal-derived complex chemical substances, ie, those contained in the European Inventory of Existing Commercial Chemical Substances, have been classified for carcinogenicity in the twenty-first adaptation to technical progress of the European Commission (EC) Dangerous Substances Directive 1994 67/548/EEC (57). The EC Regulation 793/93 requires data sets to be submitted by producers or importers to the... 

Thiophene and 3-methylthiophene are Hsted on the TSCA chemical substances inventory. Thiophene is regulated as a hazardous material under OSHA and also regulated under the Clean Air Act, Section 110, 40 CFR 60.489, but there are no exposure limits or controls set for 3-methylthiophene. Both materials are regulated under sections 311/312 of the Superfund Amendments and Reauthorization Act, 1986 (SARA), as materials with an acute health and fire hazard, and under the Resource Conservation and Recovery Act, as ignitable hazardous wastes (DOOl). 

All four butanols are registered ia the United States on the Environmental Protection Agency Toxic Substances Control Act (TSCA) Inventory, a prerequisite for the manufacture or importation for commercial sale of any chemical substance or mixture ia quantities greater than a 1000 pounds (454 kg). Additionally, the manufacture and distribution of the butanols ia the United States are regulated under the Superfund Amendments and Reauthorization Act (SARA), Section 313, which requires that anyone handling at least 10,000 pounds (4545 kg) a year of a chemical substance report to both the EPA and the state any release of that substance to the environment. 

Furthermore, increased governmental scmtiny of chemical substances will make it more difficult to bring a new product to market. The choice of comonomers and copolymers maybe based pardy on EPA, EDA, OSHA, and TSCA rulings. In addition to these regulations, the thmst toward recycling polymers is expected to impact copolymer production. The abiUty to recover and reprocess these materials will be a key factor for economic success. 

The Toxic Substances Control Act (TSCA) was enacted in 1976 to identify and control toxic chemical ha2ards to human health and the environment. One of the main provisions of TSCA was to estabUsh and maintain an inventory of all chemicals in commerce in the United States for the purpose of regulating any of the chemicals that might pose an unreasonable risk to human health or the environment. An initial inventory of chemicals was estabhshed by requiring companies to report to the United States Environmental Protection Agency (USEPA) all substances that were imported, manufactured, processed, distributed, or disposed of in the United States. Over 50,000 chemical substances were reported. PoUowing this initial inventory, introduction of all new chemical substances requires a Premanufacturing Notification (PMN) process. To be included in the PMN are the identity of the new chemical, the estimated first year and maximum production volume, manufacture and process information, a description of proposed use, potential release to the environment, possible human exposure to the new substance, and any health or environmental test data available at the time of submission. In the 10 years that TSCA has been in effect, the USEPA has received over 10,000 PMNs and up to 10% of the submissions each year are for dyes (382)... 

Catastrophic release Under OS HA PSM and EPA RMP, it means a major uncontrolled emission, fire, or explosion, involving one or more highly hazardous chemical substances (per OSHA) or regulated substances (per EPA) that presents serious danger to employees in the workplace (per OSHA) or imminent and substantial endangerment to public health and the environment (per EPA). 

CRS provides information on chemical substances and how they are represented in the Environmental Protection Agency regulations and data systems. A search engine for chemicals by CAS number, name, molecular formula, chemical type, definition, or other data identifiers. 

Directive 2004/10/EC of the European Parliament and of the Council of 11 February 2004 on the harmonisation of laws, regulations and administrative provisions relating to the application of the principles of good laboratory practice and the verification of their applications for tests on chemical substances... 

Council Directive 67/548/EEC of 27 June 1967 on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Annex 1 of the directive assigns Risk Phrases to chemical substances. 

Labour regulations, based on the European regulations, set a real instability code, which has to appear on the labelling of chemical substance containers. This code defines the following risk indications (decree from 10.10.1983) ... 

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