Skin Irritation or Dermatitis

CHRONIC HEALTH RISKS prolonged exposure may cause severe skin irritation or dermatitis persons with pre-existing skin disorders or eye problems, or impaired liver, kidney or respiratory function may be more highly susceptible to the effects of this substance. 

Handling or processing conventional U.S. cotton does not cause skin irritation or dermatitis. Cellulose is essentially an inert substance and nothing on the fiber surface is known that... 

Toxicology. Frequent/prolonged contact may cause skin irritation or dermatitis TSCA listed... 

Skin eontaet with metalworking fluids may eause skin irritation or a eontaet initant dermatitis. Contaet with neat oils may eause follieulitis (oil aene). Contaet with some aqueous-mix fluids may, depending upon the additives, e.g. bioeides, eause an allergie eontaet dermatitis. Formerly the use of unrefined mineral oils posed a risk of skin eaneer. 

Eye contact with liquid cyclohexanone may cause corneal injury. The liquid is a defatting agent, and prolonged or repeated skin contact may produce irritation or dermatitis. Allergic contact dermatitis has been reported in... 

Exposure to naphthalene can cause a severe hemolytic crisis in some individuals with a genetically linked metabolic defect associated with insufficient activity of the glucose-6-phosphate dehydrogenase enzyme in red blood cells.10 Effects include anemia and marked reductions in red cell count, hemoglobin, and hematocrit. Contact of naphthalene with skin can result in skin irritation or severe dermatitis in sensitized individuals. In addition to the hemolytic effects just noted, both inhalation and ingestion of naphthalene can cause headaches, confusion, and vomiting. Kidney failure is usually the ultimate cause of death in cases of fatal poisonings. 

Appropriate procedures should be instituted for anyone overcome by nitromethane (e.g., removal from exposure to fresh air, washing skin areas, and irrigation of eyes with water). Treatment for pulmonary irritation or dermatitis may be needed if symptoms are present. 

CHRONIC HEALTH RISKS repeated or prolonged contact with skin may produce severe irritation or dermatitis lungs may be affected by repeated or prolonged exposure to dust particles. 

External applications of raw garlic may cause skin irritation, contact dermatitis, or chemical bum (Friedman et al. 2006). 

Dermatitis is an inflammation caused by defatting of the skin or by contact with an irritating or sensitizing substance. Exposure to solvents often removes oils that keep the skin soft and pliable. Without the oil, the skin is dry, scaly, and tends to crack easily. Such skin has poor resistance to bacterial infections and heals slowly when injured. A primary skin irritant causes dermatitis almost immediately by direct action on the skin. After a while, a person may become sensitized to a chemical. A sensitizer may not cause injury immediately, but will produce susceptibility to a second attack or to other substances. Where sensitivity or allergy dermatitis exists and the skin is affected even by small amounts of the chemical, the affected worker should not be allowed in areas where the chemical is used. 

Toxicolcyy High vapor cones, may cause headaches, stupor, throat/eye irritation, kidney effects extreme aspiration Into lungs may cause pneumonia or death may cause si. eye Irritation may cause skin irritation, redness, dermatitis on prolonged/repeated contact Environmental Inherently biodeg. 

Gloves of various design provide protection against a range of hazards including cuts and abrasions extremes of temperature (hot and cold) skin irritation and dermatitis and contact with toxic or corrosive liquids. Barrier creams may sometimes be used as an aid to skin hygiene in situations where gloves cannot be used. 

Properties Colorless to straw liq. mild odor insol. in water m.w. 234.32 dens. 1.059 b.p. 95-100 C (3 mm) flash pt. (COC) 123 C ref. index 1.4155 Toxicology Severe eye irritant may produce skin irritation or contact dermatitis inh. of vapors or particulates may irritate respiratory tract on contact with water this compound liberates methanol which is known to have a chronic effect on the CNS... 

Properties Water-wh. oily liq. hydrocarbon odor sol. 1.4 ppm in water (38 C) sp.gr. 0.809 (16 C) vapor pressure 1.1 Torr (38 C) m.p. < -70 C b.p. 150 C flash pt. (TCC) 65 C Toxicology High vapor cones, may cause headaches, stupor, throat/eye irritation, kidney effects extreme aspiration into lungs may cause pneumonia or death may cause si. eye irritation may cause skin irritation, redness, dermatitis on prolonged/repeated contact suspected carcinogen TSCA listed Environmental Inherently biodeg. 

Water and other liquids make leather slippery and cause it to deteriorate. Wet gloves are uncomfortable to wear and they may also cause skin irritation or even irritant contact dermatitis (Estlander and Jolanki 1988). 

Many chemicals used in the workplace can damage the body. Effects range from skin irritation and dermatitis to chronic lung diseases such as silicosis and asbestosis or even cancer. The body may be harmed at the point where a chemical touches or enters it. This is called a local effect. When the solvent benzene touches the skin, it can cause drying and irritation (local effect). 

Note 8 Warning—Harmful if inhaled. High concentrations can cause unconsciousness or death. Contact may cause skin irritation and dermatitis. 

Toxicology LD50 (oral, rat) > 5 g/kg mineral oil mist ACGIH TWA Omg/m, STEL 10 mg/m prolonged or repeated contact may lead to skin irritation by dermatitis or oil acne oil deposits in lungs may lead to fibrosis and reduced pulmonary function aspiration may cause pulmonary edema or aspiration pneumonia TSCA listed... 

Toxicology Severe eye Irritant can cause skin Irritation or contact dermatitis resp. tract Irritant... 

Hydrogen chloride in air can also be a phytotoxicant (88). Tomatoes, sugar beets, and fmit trees of the Pmnus family are sensitive to HCl in air. Exposure of concentrated hydrochloric acid to the skin can cause chemical bums or dermatitis. Whereas the irritation is noticed readily, the acid can be water flushed from the exposed area. Copious use of miming water is the only recommended safety procedure for any external exposure. Ingestion is seldom a problem because hydrochloric acid is a normal constituent of the stomach juices. If significant quantities are accidentally swallowed, it can be neutrali2ed by antacids. 

Uncured resins are skin sensitizers and contact should be avoided, as weU as breathing the vapor, mist, or dust. Novolak-based pulverized products generally contain hexamethylenetetramine, which may cause rashes and dermatitis. PhenoHc molding compounds and pulverized phenoHc adhesives must be controUed as potentially explosive dusts. In addition, they contain irritating or toxic additives. 

Eye contact can cause irritation or bums. Repeated skin contact can result iu dermatitis. Exposure to excessive vapor concentrations irritates the eyes and respiratory tract. Very high concentrations have a narcotic effect (43). 

The first -PDA antiozonants were low molecular weight -diaLkyl-/)-PDAs which caused skin irritations. Current higher molecular weight -dialkyl or A/-alkyl-AT-aryl derivatives are not primary skin irritants. A notable exception is A/-(I-methylethyl)-A7-phenyl-/)-PDA, which causes dermatitis. However, since some individuals are more sensitive than others, antiozonants should always be handled with care (46). When skin contact does occur, the affected area should be washed with mild soap and water. In case of eye contact, flush weU with water. Inhalation of mbber chemicals should be avoided, and respiratory equipment should be used in dusty areas. 

Dinitrofluorobenzene (Sanger s reagent) [70-34-8] M 186.1, m 25-27 , b 133 /2mm, 140-141 /5mm, d 1.483. Crystd from ether or EtOH. Vacuum distd through a Todd Column (see p. 174). If it is to be purified by distn in vacuo, the distn unit must be allowed to cool before air is allowed into the apparatus otherwise the residue carbonises spontaneously and an EXPLOSION may occur. The material is a skin irritant and may cause serious dermatitis. 

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