Allergy dermatitis

Lamb SR, Wilkinson SM. Contact allergy to progesterone and estradiol in a patient with multiple corticosteroid allergies. Dermatitis 2004 15 78-81. 

Toxicity Picric acid causes adverse effects on the skin of animals and humans like allergies, dermatitis, irritation, and sensitization. Absorption of picric acid by the system causes headache, fever, nausea, diarrhea, and coma. In high concentrations, picric acid is known to cause damage to erythrocytes, kidney, and liver.68 69... 

Synonyms and trade names picronitric acid, 2,4,6-trinitrophenol, trinitrophenol Use and exposure Picric acid is a white to yellowish crystalline substance and highly flammable. It is used in the manufacture of fireworks, matches, electric batteries, colored glass, explosives, and disinfectants. Pharmaceutical, textile, and leather industries also make use of picric acid. Bouin s picro-formol is used as a preservative solution for biological specimens in laboratories. Toxicity and health effects Picric acid causes different adverse effects on the skins of animals and humans, like allergies, dermatitis, irritation, and sensitization. Absorption of picric acid by the system causes headache, fever, nausea, diarrhea, and coma. In high concentrations, picric acid is known to... 

Ni Allergies, dermatitis, lung cancer, vertigo, dizziness... 

Dermatitis is an inflammation caused by defatting of the skin or by contact with an irritating or sensitizing substance. Exposure to solvents often removes oils that keep the skin soft and pliable. Without the oil, the skin is dry, scaly, and tends to crack easily. Such skin has poor resistance to bacterial infections and heals slowly when injured. A primary skin irritant causes dermatitis almost immediately by direct action on the skin. After a while, a person may become sensitized to a chemical. A sensitizer may not cause injury immediately, but will produce susceptibility to a second attack or to other substances. Where sensitivity or allergy dermatitis exists and the skin is affected even by small amounts of the chemical, the affected worker should not be allowed in areas where the chemical is used. 

In humans, cases of dermatitis have been described after contact with DHBs. Combined exposure to hydroquinone and quinone airborne concentrations causes eye irritation, sensitivity to light, injury of the corneal epithelium, and visual disturbances (126). Cases with an appreciable loss of vision have occurred (127). Long-term exposure causes staining due to irritation or allergy of the conjunctiva and cornea and also opacities. Resorcinol and catechol are also irritants for eyes. 

Its chief use is as a component in photographic developers. Because the free compound is unstable in air and light, it is usually marketed as the sulfate salt [55-55-0] Metol, mp 260°C (dec.). It also finds appHcation as an intermediate for fur and hair dyes and, under certain circumstances, as a corrosion inhibitor for steel. Prolonged exposure to 4-(/V-methy1amino)pheno1 has been associated with the development of dermatitis and allergies. 

Prolonged contact with certain chromium compounds may produce allergic reactions and dermatitis in some individuals (114). The initial response is usually caused by exposure to Cr(VI) compounds, but once the allergy is estabUshed, it is extended to the trivalent compounds (111,115). There is also limited evidence of possible chromium associated occupational asthma, but there is insufficient data to estimate a dose for assumed chromium-induced asthma. Reference 116 provides a summary and discussion of chromium hypersensitivity. 

Some niekel eompounds may be irritant to skin and eyes and dermal eontaet with niekel ean result in allergie eontaet dermatitis. Niekel earbonyl is extremely toxie by inhalation and should be handled in totally enelosed systems or with extremely effieient ventilation. Air monitors linked to alarms may be required to deteet leaks. Respiratory equipment must be available for dealing with leaks. Biologieal eheeks (e.g. niekel in urine) should be eonsidered for routine operations involving niekel eatalysts. 

Skin eontaet with metalworking fluids may eause skin irritation or a eontaet initant dermatitis. Contaet with neat oils may eause follieulitis (oil aene). Contaet with some aqueous-mix fluids may, depending upon the additives, e.g. bioeides, eause an allergie eontaet dermatitis. Formerly the use of unrefined mineral oils posed a risk of skin eaneer. 

Breit S, Rueff F, PrzybiUa B Deep impact contact allergy after subcutaneous injection of local anesthetics. Contact Dermatitis 2001 45 296-297. Orasch CE, Helbling A, Zanni MP, Yawalkar N. Hari Y Pichler WJ T-cell reaction to local anaesthetics relationship to angioedema and urticaria after subcutaneous application-patch testing and LTT in patients with adverse reaction to local anaesthetics. Clin Exp Allergy 1999 29 1549-1554. 

Dermal Effects. Some humans experienced dry throats following acute inhalation exposure to trichloroethylene at 200 ppm (Stewart et al. 1970). Persons working with trichloroethylene for intermediate periods sometimes develop skin rashes and dermatitis (Bauer and Rabens 1974 El Ghawabi et al. 1973). It is reported that some people may be particularly sensitive to trichloroethylene and develop allergies when exposed to high levels in the air or on their skin during oeeupational exposures of intermediate duration (Cziijak et al. 1993 Goh and Ng 1988 Nakayama et al. 1988 Phoon et al. 1984). Exposure to... 

Skin diseases are the second most common form of occupational disease with contact dermatitis accounting for 10 to 15% of all occupational illnesses with an annual associated cost of at least 1 billion [7], Although irritant dermatitis accounts for the majority of cases of contact dermatitis, studies have reported that contact allergies are relevant in between 20 to 50% of contact dermatitis cases [8], In 2003 there were 49 cases of occupational skin disease reported for every 100,000 workers in private... 

Smith, H.R., et al., Irritant thresholds in subjects with colophony allergy. Contact Dermatitis, 42, 95, 2000. 

Bassioukas, K., Orton, D., and Cerio, R., Occupational airborne allergic contact dermatitis from garlic with concurrent Type I allergy, Contact Dermatitis, 50, 39, 2004. 

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