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Regulated proteins

The presence of this common helix-turn-helix motif poised for DNA binding in lambda Cro and repressor provided considerable stimulus for further genetic and structural studies of these and other procaryotic DNA-binding proteins. All the results essentially supported the proposed mode of binding between these regulator proteins and DNA. [Pg.135]

Disorders caused by misfolded mutant proteins that fail to pass the quality control system of the ER (e.g., mutations of the cystic fibrosis transmembrane regulator protein (CFTR) causing cystic fibrosis). The mutant proteins are retrotranslocated into the cytosol and finally subjected to proteolysis. In some... [Pg.1017]

Pelham, H.R.B. (1986). Speculations on the functions of the mayor heat shock and glucose regulated proteins. Cell 46,959-961. [Pg.458]

Mammalian proteins are the targets of a wide range of covalent modification processes. Modifications such as glycosylation, hydroxylation, and fatty acid acylation introduce new structural features into newly synthesized proteins that tend to persist for the lifetime of the protein. Among the covalent modifications that regulate protein function (eg, methylation, adenylylation), the most common by far is phosphorylation-dephos-phorylation. Protein kinases phosphorylate proteins by... [Pg.77]

Calcineurin Cytosol A calmodulin-regulated protein phosphatase. May play important roles in cardiac hypertrophy and in regulating amounts of slow and fast twitch muscles. [Pg.566]

PKA and PKC are, however, not the only kinases to regulate TRPVl. The Ca /calmodulin-dependent kinase II (CaMKII) sensitizes TRPVl by phosphorylation [57, 58], as does phophatidylinositol 3-kinase (PI3K) via its downstream target AKT [59]. This latter finding links TRPVl to the ERK (extracellular signal-regulated protein kinase) pathway. The non-receptor tyrosine kinase Src likewise potentiates capsaicin-induced currents [60]. [Pg.150]

Ducommun, B., Draetta, P., Young, P and Beach, D. (1990). Fission yeast cdc25 is a cell-cycle regulated protein. Bichem. Biophys. Res. Commun. 167 301-307. [Pg.38]

Osmani, A. H., McGuire, S. L., and Osmani, S. A. (1991). Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans. EMBO J. 67 283-291. [Pg.48]

How might cellular growth drive Gl/S transitions A mechanism in which an unstable, translationally regulated protein limits Gl/S transitions provides one possible explanation. Consistent with this, we found that ectopic Rasvl2 or d-Myc increased levels of cyclin E, and that this effect was post-transcriptional (Prober ... [Pg.9]

Nakayama, H., Numakawa, T., Ikeuchi, T., Hatanaka, H. Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells. J. Neurochem. 79 489, 2001. [Pg.36]

A. Sreekumar, M.K. Nyati, S. Varambally, T.R. Barrette, D. Ghosh, T.S. Lawrence, and A.M. Chinnaiyan, Profiling of cancer cells using protein microarrays discovery of novel radiation-regulated proteins. Cancer Res. 61, 7585-7593 (2001). [Pg.400]

A few hours after eating, the supply of easily available nutrients has been used up and stores must be mobilized to maintain relatively constant supplies of energy and glucose (Fig. 17-7). Insulin levels drop and glucagon levels rise. Because of the increased glucagon levels, cAMP levels rise and regulated proteins become more phosphorylated. [Pg.227]


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Biomineralization Regulated by Silk Proteins

CGMP-regulated protein kinase

Calcium binding proteins regulation

Calcium-dependent regulator protein

Calcium/calmodulin-dependent protein kinases activity regulation

Cell cycle protein modulation signaling regulation

Contractile proteins tissue specific and developmentally regulated gene expression

Cystic fibrosis transmembrane conductance regulator CFTR) protein

Cystic transmembrane regulator protein

Diphtheria toxin regulator protein

Enzymes nonhistone proteins, regulated

Eucaryote signals-regulated protein

Eucaryote signals-regulated protein kinase

External signal-regulated protein kinase

Extracellular regulated protein kinase

Extracellular signal-regulated kinase MAPK protein expression

Extracellular signal-regulated protein kinase

Extracellular signal-regulated protein kinase pathway)

Ferric uptake regulation protein

G protein-coupled receptor regulation

G-protein regulators

GLUT regulator protein

Gene regulation proteins

Glucose-regulated protein

Glycogen synthase regulation protein phosphatase

HAT Proteins Function in Regulating Transcriptional Elongation

Homeostatic regulation protein

Insulin protein biosynthesis regulation

Iron regulator 7 protein

Kinetics, regulated proteins

Mitogen-activated protein kinase regulation

Mitogen-regulated protein

Phosphorylation, protein regulation

Promoters glucose-regulated protein

Protein Phosphorylation and Regulation of Glycogen Metabolism

Protein activity regulation

Protein antioxidant, transcriptional regulation

Protein biosynthesis regulation

Protein degradation, regulated

Protein expression regulation

Protein formation, mechanisms regulation

Protein kinase A in regulation of ionotropic

Protein kinase Regulation

Protein kinase activity regulation

Protein kinase calcium pump regulation

Protein kinase enzyme regulation

Protein kinase pharmacological regulation

Protein kinase regulators

Protein kinase smooth muscle contraction regulation

Protein oxidation regulation

Protein phosphatases regulation

Protein prokaryotic regulators

Protein regulated pathways

Protein regulation covalent modification

Protein stability regulator

Protein synthesis and regulation

Protein synthesis regulation

Protein synthesis-regulating receptors

Protein tyrosine kinases pharmacological regulation

Protein tyrosine kinases regulation

Protein tyrosine phosphatase Negative regulation

Protein tyrosine phosphatase Positive Regulation

Protein tyrosine phosphatase Regulation

Protein tyrosine phosphorylation intracellular calcium regulation

Protein-Nucleic Acid Interactions as a Basis for Specific Gene Regulation

Proteins biological regulation

Proteins ferric-uptake regulator

Proteins regulating sphingolipid synthesis

Proteins regulation

Proteins, introduction function, regulation

RGS proteins, regulation of G protein

RGS proteins, regulation of G protein signaling

Regulates Axin Protein Levels by Inhibiting Tankyrases

Regulation nuclear receptor proteins

Regulation of Chemokine Expression by STAT Proteins

Regulation of Eucaryotic Transcription by DNA-binding Proteins

Regulation of Protein Activity

Regulation of Protein Catabolism

Regulation of Protein Kinase

Regulation of Protein Kinase C Activity

Regulation of Protein Tyrosine Phosphatases

Regulation of Proteins by Sumoylation

Regulation of protein expression

Regulation of protein synthesis

Regulator of G-protein signaling (RGS

Regulators of G protein-signaling

Regulators of G-protein Signalling

Regulators, Cdc2 protein kinase

Retinoblastoma protein , cell cycle regulation

Signal regulated protein kinases

Sterol regulatory element-binding proteins fatty acid regulator

Stress activated protein kinases gene expression regulated

Subunit Structure and Regulation of Protein Phosphatases

Synthesis of Repair Proteins Is Regulated

The Regulation of Protein Biosynthesis

Translation expression/regulation Protein

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