GLUT regulator protein

Regulator proteins also play a role in how much energy is made available to muscles. An example is the GLUT regulator protein, which sits on the surface of muscle tissue. Its function is to pull glucose, an energy-rich sugar molecule, from the blood-... 

There is an intracellular feedback loop that regulates protein folding. The ER inside eukaryotic cells serves as a cellular factory where newly synthesized proteins are folded into their proper structures. If the ER cannot keep up with demands, then unfolded or misfolded proteins pile up awaiting processing. This glut of unfolded proteins is detected by a series of enzymes that then activate genes to... 

In addition to secretory cells, many non-secretory cells are capable of regulating exocytotic fusion of transport vesicles that are derived from endosomal precursors. For instance, vesicles enriched in plasma membrane transport proteins are incorporated in a regulated manner in order to alter metabolite fluxes. Examples include the glucose transporter GLUT-4 in muscle and fat tissues, a key element in the control of... 

Glucose transport activity is regulated through transcriptional and translational control of the GLUT proteins, through their activity, and through alterations of their intracellular distribution. Most importantly, the GLUT4 continuously cycles between an intracellular,... 

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