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Protein antioxidant, transcriptional regulation

Huang HC, Nguyen T, Pickett CB. 2002. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J Biol Chem 277 42769—42774. [Pg.421]

Favreau LV, Pickett CB. 1993. Transcriptional regulation of the rat NAD(P)H quinone reductase gene. Characterization of a DNA-protein interaction at the antioxidant responsive element and induction by 12-O-tetradecoylphorbol 13-acetate. J Biol Chem 268 19875-19881. [Pg.617]

Fatma, N., D.P. Singh, T. Shinohara and L.T. Chylack, Jr. Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress. J. Biol. Chem. 276 48899—48907, 2001. [Pg.389]

Transcriptional regulation of antioxidant proteins. Certain proteins with easily accessible Fe-S clusters, e.g., aconitase, are readily inachvated by oxidants such as perox5mitrite. At least two proteins of this type function as transcription factors in E. coli. These are known as SoxR and OxyR. The SoxR protein is sensihve to superoxide anion, which carries out a one-electron oxidahon on its Fe2S2 centers. ... [Pg.141]

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Protein transcription

Protein transcripts

Proteins antioxidant

Regulated proteins

Regulation transcription

Transcriptional regulation

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