Marketed Databases

Beilstein is a much more comprehensive database, marketed under the name of MDL Crossfire, and requires a subscription fee for access. It contains far more organic substances and lists many more properties. The search commands include ... 

Some safety issues for excipients with a history of use may be addressed by citations of the clinical and nonclinical database, marketing history, or regulatory status of the compound, e.g., GRAS status as a direct food additive may support oral administration of that product up to the levels allowed in foods. 

In a recent article, the FDA stated For excipients with a history of use, it may be possible to adequately address some or all of the safety issues through citation of the existing nonclinical and clinical database, marketing history, or regulatory status of the compound (e.g., GRAS status as a direct food additive may adequately support oral administration of that compound up to the levels permitted in foods) (25). Therefore, it appears reasonable that the FDA would consider the use safety data based on the food additive regulatory status of an excipient to evaluate the safety of the excipient. If a new excipient has undergone a food additive safety review, this may reduce the perceived risks associated with the development and use of a new excipient. 

Systems Customer database Market research systems Geo aphicinicrmaion systems... 

Kamakura, W., Wedel, M, de Rosa, F. and Mazzon, J., 2003. Cross-selling through database marketing A mixed data factor analyser for data augmentation and prediction. Intematiorud Journal of Research in Marketing 20,45-65. 

Customer Relationship Management Customer segmentation Customer analytics Data sharing Joint business goals Network market knowledge Joint technology adoption Database marketing... 

With a smart database, marketers can easily target their subscribers using demographic AND behavioral filters and... 

The marketed spectra databases are sold by institutes, constructors of mass spectrometers, editors on CD-ROM, or by download. Publicity put aside, the two most well known are, by far, the NIST database (from the American National Institute of Standard and Technology) and the WILEY database (marketed by the famous scientific editor). These are databases that index mass spectra recorded in electron ionization at 70 eV. Generally speaking, the few marketed databases devoted to chemical ionization are not very reliable. With this soft ionization mode, the characteristics of spectra depend greatly on conditions of tanperature and pressure withiu the source. For that reason, spectral reproducibility in Cl from one mass spectrometer to another is generally mediocre. 

Sf The Chemlnjbrm RX reaction database is produced by FIZ Chemie, Berlin, Germany, and marketed by MDL Information Systems, Inc., San Leandro, CA, USA. 

Data-Star. This is Europe s leading on-line database service (39) and covers worldwide business news, financial information, market research, trade statistics, business analysis, healthcare / pharmaceuticals, chemicals / petrochemicals, chemical industry, biomedicine /life science, biotechnology, and technology, with an emphasis on Europe. It was originally formed as a joint venture among BRS, Predicasts, and Radio Suisse (the Swiss telecommunications company) (37). Data-Star offers access to about 300 bibliographic, abstract, directory, and fuU-text on-line databases, of which approximately 150 are also available on Dialog (40). 

Nuclear Magnetic Resonance Spectroscopy. Bmker s database, designed for use with its spectrophotometers, contains 20,000 C-nmr and H-nmr, as weU as a combined nmr-ms database (66). Sadder Laboratories markets a PC-based system that can search its coUection of 30,000 C-nmr spectra by substmcture as weU as by peak assignments and by fiiU spectmm (64). Other databases include one by Varian and a CD-ROM system containing polymer spectra produced by Tsukuba University, Japan. CSEARCH, a system developed at the University of Vieima by Robien, searches a database of almost 16,000 C-nmr. Molecular Design Limited (MDL) has adapted the Robien database to be searched in the MACCS and ISIS graphical display and search environment (63). Projects are under way to link the MDL system with the Sadder Hbrary and its unique search capabiHties. 

Secondary sources of data are useful when they exist. Databases (qv) of pubUshed information have been assembled, and market researchers can tap them provided their company buys the service. These databases can save the market analyst many hours of work. The services also provide much of the general sociopolitical—economic background needed, such as petroleum (qv) prices, government regulations, foreign competition, etc. 

Chemically related database searches can be used to estabhsh concepts and patentable ideas. For instance, searches have identified researchers using particular monomers in a potentially patentable latex formulation found precedents for a polymeric emulsifier summarized pubHcations of people being considered as consultants, expert witnesses, employees or speakers to an industrial group and provided market description information for a new pigment manufacturing firm to identify target markets. 

Whereas Figure 1 represents worldwide data for all types of pubHcly available databases. Figure 2, showing growth in database searches, represents only a portion of those databases, ie, U.S. usage of word-oriented databases in the information center/Hbrary market. 

The Predicasts Overview of Markets and Technologies (PROMT) is a database that provides international coverage of companies, products, markets, and applied technologies for industries. PROMT abstracts more than 1000 worldwide business publications. PROMT derives information from ... 

Plastics Institute) established the materials database called Polymat. This program brings greater availability into a plastics market in which a general perspective is becoming increasingly difficult to obtain. This database contains information on plastics and elastomers, supplying about thirty to fifty properties for each material. Initially some six thousand plastics, from about seventy manufacturers, were stored. 

The concept of the Polymat database was based on the following criteria (1) the data-base is neutral, independent of raw-material manufacturers (2) anyone can use the database (3) all the products on. the European market should, if possible, be included (4) since testing is carried out in accordance with a variety of different international standards, the relevant standard, as well as the testing conditions, is registered (5) during the search, all properties should be capable of being linked with one another as desired and (6) the sources used for the database are the technical data sheets and additional information supplied by raw-material manufacturers, and various lectures, publications, and measured data from different institutes. 

The manufacturers database, Campus, provides use that is free of charge and no charges for data transmission. The actual value of the table of basic values described in Campus lies in its effect on the standardization and streamlining of testing. In the long term, the nonparticipants in the material market will not be able to remain outside this development. 

With regard to the common European market, the European Economic Community (EEC) has undertaken numerous activities concerned with materials and material information systems. In one demonstration program for material databases eleven such databases from various countries in the EEC are being cooperatively developed with joint standards for terminology, data presentation, database access, and the user interface of search commands, aids, and menus. For the materials class of plastics, Polymat was selected to participate in this cooperative work. Interesting developments occur from which the users of central material databases in the entire EEC area can benefit. 

Search MSDS on CCINFOWeb. All databases on CCINFOWeb may be searched for free. The MSDSs are contributed by North American sources, many that are multi-national companies marketing chemical products worldwide. This database meets a growing international requirement for health and safety information on specific chemical products. It helps thousands of users worldwide manage their responsibilities under workplace, environmental and other right-to-know legislation. The MSDS database can be searched quickly and easily for product names and other product identifications, manufacturer or supplier names, dates of MSDSs, or any term used in the text of the MSDS itself. 

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