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Cells infection

The mechanism of inhibition has not been characterized, but it is probably related to the ionophoretic properties of these antibiotics. Monensin has been shown to inhibit the intracellular transport of viral membrane proteins of cells infected with Semliki Forest vims (169). The formation of syncytia, normally observed when T-lymphoblastoid cell line (CEM) cells are cocultivated with human immunodeficiency vims (HlV-l)-infected T-ceU leukemia cell line (MOLT-3) cells, was significantly inhibited in the presence of monensin (170). This observation suggests that the viral glycoproteins in the treated cells were not transported to the cell surface from the Golgi membrane. [Pg.172]

BVdU differs from IdU and F TdU by being specifically phosphorylated in the 5 -position by herpes simplex vims type-1 (HSV-1) induced thymidine kinase. This restricts its action to cells infected by HSV-1. It is less active against genital herpes (HSV-2). HSV-l-induced thymidine kinase converts BVdU to the corresponding 5 -mono- and diphosphate, but HSV-2-induced thymidine kinase stops at the stage of the 5 -phosphate of BVdU. Apparendy, cellular kinases phosphorylate BVdU-5 -diphosphate to the corresponding 5 -triphosphate, which inhibits HSV-1 DNA polymerase to a greater extent than similar cellular DNA polymerases. [Pg.305]

Infected Cells Infected cells are assumed to gradually, and linearly, approach the ill state as a function of the average degree of infection in their neighborhood. Define Sij t) as the average degree of infection of sites neighboring site (bi) at time ... [Pg.424]

Opportunistic infection, eg. CMV Progressive polyradiculopathy AIDS Acute, subacute Multiple, asymmetric mononeuropathies, usually painful CMV infection, Schwann cell infection demyelinating neuropathy... [Pg.53]

VZV radiculopathy or myeloradiculopathy AIDS Acute Lumbosacral pain saddle anesthesia rapidly progressive flaccid paraparesis VZV infection Schwann ceU-endothelial cells infection... [Pg.53]

Gelman BB, Wolf DA, Rodriguez-Wolf M et al (1997) Mononuclear phagocyte hydrolytic enzyme activity associated with cerebral HIV-1 infection. Am J Pathol 151 1437-1446 Giraudon P, Buart S, Bernard A et al (1997) Cytokines secreted by gUal cells infected with HTLV-I modulate the expression of matrix metalloproteinases (MMPs) and their natural inhibitor (TIMPs) possible involvement in neurodegenerative processes. Mol Psychiatry 2(107-10) 84... [Pg.168]

NK cells are a subset of lymphocytes found in blood and lymphoid tissues, especially the spleen. They are about 15 an in diameter, possess a kidney-shaped nucleus and have two or three large granules in the cytoplasm. They are derived from the bone marrow. NK cells have the ability to kill certain tumour lines and normal cells infected by virus. Killing by NK cells is not specific for viral antigenic epitopes, and is not restricted by MHC molecules. They do not possess CD3 but do express CD2, CD 16 and CD56, together with a low-affinity receptor for the Fc portion of IgG. [Pg.297]

Hepatitis At Human diploid cells infected with hepatitis A virus 1 Separation of virus from cells 2 Inactivation with HCHO 3 Adsorption toAI(OH)3gel Assay of antigen content by ELISA Inoculation of cell cultures to exclude presence of live virus... [Pg.313]

Lauer, S. A. Rathod, P. K. Ghori, N. Haider, K. A. A membrane network for nutrient import in red cells infected with the malaria parasite. Science 1997, 276, 1122-1125. [Pg.179]

Momma, Y, Nagineni, CN, Chin, MS, Srinivasan, K, Detrick, B, and Hooks, JJ, 2003. Differential expression of chemokines by human retinal pigment epithelial cells infected with cytomegalovirus. Invest Ophthalmol... [Pg.348]

Due to lack of specific reagents, products of 8- and y-stichocytes were not evaluated in irradiated larval experiments and cannot be excluded from a role in the muscle infection. Interestingly, NA were detected in nuclei of muscle cells infected by irradiated larvae, which suggested that these products may influence the infected cell phenotype but are not derived Irom a- and P-stichocytes. [Pg.138]

SCHEME 60. Galactosylated PPI dendrimers used as inhibitors of cell infectivity by HIV-1.419... [Pg.339]

Vaccination to induce an adaptive immune response is expected for a broad range of infectious diseases and cancers. Traditional vaccines are mainly composed of live attenuated viruses, whole inactivated pathogens, or inactivated bacterial toxins. In general, these approaches have been successful for developing vaccines that can induce an immune response based on antigen-specific antibody and cytotoxic T lymphocyte (CTL) responses, which kill host cells infected with intracellular organisms (Fig. 1) [1,2], One of the most important current issues in vaccinology is the need for new adjuvants (immunostimulants) and delivery systems. Many of the vaccines currently in development are based on purified subunits, recombinant... [Pg.33]

Obrig TG, Del Vecchio PJ, Brown JE, Moran TP, Rowland BM, Judge TK, Rothman SW Direct cytotoxic action of Shiga toxin on human vascular endothelial cells. Infect Immun 1988 56 2373-2378. [Pg.33]

Navarro-Garcia F, Canizalez-Roman A, Luna J, Sears C, Nataro JP Plasmid-encoded toxin of enteroaggregative Escherichia coli is internalized by epithelial cells. Infect Immun 2001 69 1053-1060. [Pg.33]

Langer RC, Riggs MW Cryptosporidium parvum apical complex glycoprotein CSL contains a sporozoite ligand for intestinal epithelial cells. Infect Immun 1999 67 5282-5291. [Pg.34]

HSV in human fibroblasts was detected using biotin-labeled HSV DNA probes, streptavidin-HRP complex, and enhanced CL substrate reagent for HRP [56], The presence of HSV DNA was observed in cells infected with clinical samples known to contain the HSV virus fixed at 48 h postinfection, with a sharp topographical localization and a good preservation of cellular morphology. [Pg.491]

Trophoblastin, therefore, has been named interferon-tau (IFN-x), and is classified as a type I interferon. There are at least three or four functional IFN-x genes in sheep and cattle. The molecule displays a molecular mass of 19 kDa and an isoelectric point of 5.5-5.7, in common with other type I interferons. Interestingly, the molecule can also promote inhibition of reverse transcriptase activity in cells infected with the HIV virus. [Pg.236]

A relatively new cell line that has not to date been characterised for its use in biopharmaceutics is based on primary airway epithelial cells infected with retroviruses expressing hTERT and HPV-16 E6/E7 (NuLi-1) [54], NuLi-1 cells were cultured on plastic up to passage 30. When grown on collagen-coated, semi-permeable membranes (Millicell-PCF), NuLi-1 TEER decreased only slightly over the 30 passages from 685 31 to 389 21 ohm.cm2. The TEER of NuLi-1 is similar to that observed with the primary bronchial cultures of 532 147 ohm.cm2. Thus, NuLi-1 cells can form an electrically tight airway epithelial barrier that mimics active and passive ion transport properties of primary human bronchial epithelial cells [54],... [Pg.242]

Coburn, J., Magoun, L., Bodary, S. C., and Leong, J. M. (1998). Integrins a(v)p3 and o5pl mediate attachment of lyme disease spirochetes to human cells. Infect. Immun. 66, 1946-1952. [Pg.143]

Firon, N., Ashkenazi, S., Mirelman, D., Ofek, I., and Sharon, N. (1987). Aromatic alpha-glycosides of mannose are powerful inhibitors of the adherence of type 1 Escherichia coli to yeast and intestinal epithelial cells. Infect. Immun. 55,474-476. [Pg.145]

Hanski, E., Horwitz, P. A., and Caparon, M. G. (1992). Expression of protein F, the fibronectin-binding protein of Streptococcus pyrogenes JRS4, in heterologous streptococcal and enterococcal strains promotes their adherence to respiratory epithelial cells. Infect. Immun. 60, 5119-5125. [Pg.147]

Scaletsky, 1. C. A., Silva, M. L. M., and Trabulsi, L. R. (1984). Distinctive patterns of adherence of enteropathogenic Escherichia coli to HeLa cells. Infect. Immun. 45,534—536. [Pg.156]

Shoaf, K. D., Mulvey, G. L., Armstrong, G. D., and Hutkins, R. W. (2006). Prebiotic galactoo-ligosaccharides reduce adherence of enteropathogenic Escherichia coli to tissue culture cells. Infect. Immun. 74, 6920-6928. [Pg.157]

Sukupolvi, S., Lorenz, R. G., Gordon, J. I., Bian, Z., Pfeifer, J. D., Normark, S. J., and Rhen, M. (1997). Expression of thin aggregative fimbriae promotes interaction of Salmonella typhi-murium SR-11 with mouse small intestinal epithelial cells. Infect. Immun. 65,5320-5325. [Pg.158]

Torres, A. G., Zhou, X., and Kaper, J. B. (2005). Adherence of diarrheagenic Escherichia coli strains to epithelial cells. Infect. Immun. 73,18-29. [Pg.159]


See other pages where Cells infection is mentioned: [Pg.30]    [Pg.413]    [Pg.233]    [Pg.166]    [Pg.228]    [Pg.280]    [Pg.377]    [Pg.308]    [Pg.138]    [Pg.118]    [Pg.207]    [Pg.106]    [Pg.144]    [Pg.128]    [Pg.257]    [Pg.16]    [Pg.18]    [Pg.182]    [Pg.188]    [Pg.593]    [Pg.372]   
See also in sourсe #XX -- [ Pg.31 ]




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Cellular DNA Synthesis in Productively-Infected Cells

Cellular Gene Expression in Adenovirus-Infected Cells

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Hematopoietic stem cell transplant patient infections

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Infected cells

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Infection intestinal epithelial cells

Infections phagocytes cells

Insect cells infected

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Muscle cells, infected

Plasmodium falciparum infected red blood cells

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Posttranscriptional and Transcriptional Regulation of Ribosomal RNA Synthesis in Adenovirus-Infected Cells

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Productive Infection of Mouse Cells

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