Information Systems Software

Executive information system Software providing operating information for direct access by executive users. 

The basis of ALADDIN is the Daylight Chemical Information Systems software, particularly GENIE, a substructure specification language. When GENIE finds a query substructure in an input SMILES structure, it can return to the user those atoms in the structure that correspond to those hit. Since in a MENTHOR database the coordinates of the atoms are stored in the order in which they occur in the SMILES for that molecule, the coordinates of the atoms of interest are thereby identified. Thus, our geometric objects are established from this set of atoms, and geometric tests are performed on them. Steric tests are performed on molecules that meet the geometric criteria. 

SDF - structure data file, one of several formats originating from MDL Information Systems software. The MDL Molfile is a subset of the SD-file. The MDL formats are all connectivity-oriented and geared towards small molecules with up to 255 heavy atoms and structure search systems. ... 

DayCart is a software cartridge which offers a range of operation on an Oracle database, such as complete structure, similarity, and substructure search. The software can be obtained from Daylight Chemical Information Systems, Inc. (Mission Viejo CA) URL www.daylight.com... 

MDL Information Systems, Inc. MDL provides modular software systems for managing chemical information, as weU as related molecular and reaction databases for use with the software. MDL s database management programs, MACCS-II and REACCS, provide access to compound and reaction databases and also have the capabiHty to manage user-created databases (37). Although MDL is not considered to be an on-line database vendor, it is mentioned here because of the value of its information products and services to the chemical industry. 

Structure and Nomenclature Search System. This system links the collection of chemical databases found in the Chemical Information System (CIS), one of the first interactive systems for stmcture and substmcture searching. References from the separate files can be retrieved by SANSS using CAS Registry Numbers, and the database of stmctures may be searched for stmctures or substmctures. An adaptation of the SANSS software for substmcture searching has been incorporated in the Dmg Information System of the National Cancer Institute for its own use (54). 

Private (EPA) Databases. The U.S. EPA maintains a Hst of approximately 600 current information systems, as weU as some of the models and databases used within the organi2ation. The Hst is pubHshed in Information Systems Inventoy (ISI) which is updated yearly and maintained by the Information Management and Services Division of the Office of Information Resources Management (109). ISI Hsts the system name and acronym, system level, responsible organi2ation, contact person, legislative authorities, database descriptors, access information, hardware and software, system abstract, and keywords. 

Selection of LIMS software should take into account both data compatibiUty and ease of use. Since a LIMS is one information system within an organization, it may need to share data with other systems. Therefore, the software should be capable of sharing data directiy or exporting data into compatible formats. 

EE Abola, EC Bernstein, SH Bryant, TF Koetzle, J Weng. Protein data bank. In EH Allen, G Bergerhoff, R Sievers, eds. Crystallographic Databases Information, Content, Software Systems, Scientific Applications, Bonn Data Commission of the International Union of Crystallography, 1987, pp 107-132. 

There are three major steps to a patent search. (1) There is the US Patent Classification System that is a sort of subject index to all patents, (2) CASSIS is a computerized software information system provided by the USA patent office, and (3) review the patent that takes time involves the weekly official worldwide gazettes, magazines, etc. There are many ways available to search the patent database in both US and worldwide, but one web that is particularly useful to the novice or occasional searcher is one offered by IBM locate at http //www patents.IBM.com... 

IBM, a leader in information technologies, produces computer systems, software, networking systems, storage devices and microelectronics. It employs over 300,000 people and operates in over 100 countries. Business Innovation Services (BIS) is the consulting and systems integration arm of IBM Global Services. The organization is the... 

DAYLIGHT Software 4.41 (1995) Daylight Chemical Information System . Irvine, CA. 

Computers. A certain number of personal computers are necessary for report generation and regulatory submission preparation. In addition, these may be useful for record keeping, depending on the type of stability information system that the company chooses to use. Alternatively, if the information system is intended to be accessible (read only) to many users, it may be more efficient to develop a local area network of mini-computers. The size of the database will help determine the nature of the software/hardware configuration used for this function. 

Based on their corporate experience in supporting their own research and development projects as well as a number of government-sponsored activities, the development of scientific software at BBN grew out of a long history of support of a variety of scientific applications. For example, in the 1960 s, BBN developed a hospital information system for Massachusetts General Hospital which used an early minicomputer, the PDP-1, to support clinical research activities. Under the sponsorship of the National Institutes of Health, they developed a system called PROPHET (1) which provides a... 

Analysis of biological data has now become far more complex, and there is a drive to develop software to allow disparate data sets, such as sequence, literature, clinical data and expression analyses, to all be accessible and interlinked. This allows movement between information systems and provides more complex meta-ana-lyses of these data sets, allowing a holistic view of biological research, in place of the current fragmented view we have available to us. This will ultimately lead to the blurring of boundaries between different disciplines, such as the areas of che-... 

Cyber security Protection of critical information systems including hardware, software, infrastructure, and data from loss, corruption, theft, or damage. 

Abola EE, Bernstein FC, Bryant SH, Koetzle TF,Weng J (1987) In Allen FH, Bergerhoff G, Sievers R (eds) Protein data bank in crystaUographic databases-information content, software systems, scientific applications. Data Commission of the International Union of Crystallography, Bonn Cambridge Chester, pp 107-132... 

Specific guidelines for laboratory information systems include regulahons for computer conhgurahon, procedure manuals, system security, data entry/reports/ retrieval, hardware and software, and system maintenance. 

Daylight software is available from Daylight Chemical Information Systems, Inc., 27401 Los Altos, Suite 360, Mission Viejo, CA 92691. 

We thank the following Novartis Institutes for BioMedical Research for funding JH MDL Information Systems Inc. for the provision of the MDDR database Barnard Chemical Information Ltd., Daylight Chemical Information Systems Inc., the Royal Society, Tripos Inc. and the Wolfson Foundation for software and laboratory support. 

---