Haematology

H. C. Neu, in J. C. Petrie, ed.. Gastrointestinal, Haematological and Infectious Disease Therapy, Elsevier Science PubHshers, Amsterdam, The Netherlands, 1985, p. 215. 

Haematological characteristics (haemoglobin level, red blood and white blood cell counts, platelet count, blood clotting time). 

Astrid Novosel, Arndt Borkhardt Universitat Dusseldorf, Children s University Hospital, Department of Paediatric Haematology Oncology Clinical Immunology, Dusseldorf, Germany... 

Gopal K, Khanna RN, Anand M, et al. 1982. Haematological changes in fish exposed to endosulfan. 

Hobara T, Kobayashi H, Higashihara E, et al. 1984. Acute effects of 1,1,1-trichloroethane, trichloroethylene, and toluene on the haematologic parameters in dogs. Arch Environ Contam Toxicol 13 589-593. 

Shaw BP, Dash S, Panigrahi AK. 1991. Effect of methyl mercuric chloride treatment on haematological characteristics and erythrocyte morphology of Swiss mice. Environ Pollut 73 43-52. 

The diagnosis of PK deficiency depends on the determination of quantitative enzyme activity or qualitative abnormalities of the enzyme. In 1979, the International Committee for Standardization in Haematology (ICSH) established methods for the biochemical characterization of red blood cell PK variants (M22). Since the establishment of these methods, many PK-deficient cases have been characterized, including 13 cases of homozygous PK deficiency. Residual red blood cell PK activity is not usually associated with phenotypic severity,whereas enzymatic characteristics such as decreased substrate affinity, thermal instability, or impaired response to the allosteric activator fructose-1,6-diphosphate (F-1,6-DP) correspond to a more severe phenotype. 

M26. Miwa, S., Luzzatto, L., Rosa, R., Paglia, D. E., Schroter, W De Flora, A., Fujii, H., Board, P. G and Beutler, E., International Committee for Standardization in Haematology Recommended methods for an additional red cell enzyme (pyrimidine 5 -nucleotidase) assay and the determination of red cell adenosine 5 -triphosphate, 2,3-diphosphoglycerate and reduced glutathione. Clin. Lab. Haematol. 11, 131-138 (1989). 

Lentner, C. (1984). Human plasma composition (Physical chemistry, composition of the blood, haematology, sonatometric data). Geigy Scientific Tables, Vol. 3. Basle, Switzerland Ciba Geigy. 

Yuen, C.T., Stoning, P.L., Tiplady, R.J. et al. (2003) Relationships between the A-glycan structures and biological activities of recombinant human erythropoietins produced using different culture conditions and purification procedures. British Journal of Haematology, 121 (3), 511-526. 

Boreham, P.F.L. and Atwell, R.B. (1983) Adverse drug reactions in the treatment of filarial parasites haematological, biochemical, immunological and pharmacological changes in Dirofilaria immitis infected dogs treated with diethylcarbamazine. International Journal for Parasitology 13, 547-556. 

It has been well documented that the anaemia of chronic disease, ACD, results in a lowering of various haematological parameters. Several mediators are involved, among them histamine, serotonin, bradykinin, prostaglandins and, as found more recently, cytokines and nitric oxide. ACD is a parameter of systemic autoimmune disorders. The severe inflammatory stimuli lead to several systemic changes, mediated by inflammation-associated cytokines, e.g. IL-6, IL-1 TNFa, TGF beta that regulate hepatic synthesis of the acute phase proteins. 

Candida albicans Haematologic malignancies with iron overload I.2a II... 

Pignatti, F., Aronsson, B., Vamvakas, S., Wade, G., Papadouli, I., Papaluca, M., Moulon, I., and Courtois, P.L. 2002. Clinical trials for registration in the European Union the EMEA 5-year experience in oncology. Critical Reviews in Oncology Haematology 42(2), 123-135. 

Hideshima, T., Podar, K., Chauhan, D., and Anderson K. 2005. Cytokines and signal transduction. Best Practice and Research Clinical Haematology 18(4), 509-524. 

Komschlies, K.L., Grzegorzewski, K.J., and Wiltrout, R.H. 1995. Diverse immunological and haematological effects of interleukin-7 implications for clinical application. Journal of Leukocyte Biology 58, 623-631. 

Miyazaki, H. and Kato, T. 1999. Thrombopoietin biology and clinical potential. International Journal of Haematology 70(4), 216-225. 

Winslow, R. 2000. Blood substitutes refocusing an elusive goal. British Journal of Haematology 111(2), 387-396. 

Marder, V. and Stewart, D. 2002. Towards safer thrombolytic therapy. Seminars in Haematology 39(3), 206-216. 

Chakrabarti, R. and Schuster, S. 1997. L-Asparaginase - perspectives on the mechanisms of action and resistance. International Journal of Pediatric Haematology /Oncology 4(6), 597-611. 

Wepener, V., J.H.J. van Vuren, and H.H. Du Preez. 1992. The effect of hexavalent chromium at different pH values on the haematology of Tilapia sparrmanii (Cichlidae). Comp. Biochem. Physiol. 101C 375-381. 

Rai, R. and M.A. Qayyum. 1984. Haematological responses in a freshwater fish to lead poisoning. Jour. Environ. Biol. 5 53-56. 

Allen, P. 1994. Changes in the haematological profile of the cichlid Oreochromis aureus (Steindachner) during acute inorganic mercury intoxication. Comp. Biochem. Physiol. 108C 117-121. 

Chliamovitch, Y.P. and C. Kuhn. 1977. Behavioural, haematological and histological studies on acute toxicity of bis(tri-n-butyltin)oxide on Salmo gairdneri Richardson and Tilapia rendalli Boulenger. Jour. Fish Biol. 10 575-585. 

Verma, S.R., S. Rani, and R.C. Dalela. 1982b. Indicators of stress induced by pesticides in Mystus vittatus haematological parameters. Indian Jour. Environ. Health 24 58-65. 

Llacna, S., et al., Effects of air pollution on haematological parameters in passerine birds, Arch. Environ. Contam. Toxicol., 31, 148, 1996. 

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