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Glycosidases 3-Glycosidase

Digestion of lactose is facilitated by the p glycosidase lactase A deficiency of this enzyme makes it difficult to digest lactose and causes abdominal discomfort Lactose intolerance is a genetic trait it is treatable through over the counter formulations of lac tase and by limiting the amount of milk m the diet... [Pg.1048]

One of the most important differences between cellulose and starch is that animals can digest starch Because the glycosidic linkages m starch are a an animal s a glycosidase enzymes can catalyze then hydrolysis to glucose When more glucose is... [Pg.1049]

Glycosaminoglycans Glycose Glyco Serve Glycosidases Glycoside Glycosides... [Pg.449]

Three classes of oral therapeutic agent are available for treating patients with diabetes mellitiis (NIDDM) the arylsulfonylureas (known simply as sulfonylureas), biguanides, and a-glycosidase inhibitors. Since 1977, only the sulfonylureas have been approved for use in the United States, although the other classes are used elsewhere. [Pg.341]

Inhibition of configuration-retaining glycosidases by lactones, piperidines, and tetrazoles 99AG(E)750. [Pg.237]

Sinnlarly, f-i- -casuralme, a pentahydroxy pyrrolizidine alkaloid, is prepared by a tandem [4-i-3 /[3-i-3 cycloadchdon involving nitroalkene, chiral vinyl ether, and vinyl silane This process creates five of the six stereocenters present in this potent glycosidase inhibitor fScheme 8 35 ... [Pg.282]

Shiga toxins and related toxins from E. coli No proteins ( ) 28S rRNA A/-glycosidase Cleavage of 28S rRNA Inhibition of protein synthesis... [Pg.246]

Qlo Glycosidase (Glycoside hydrolase) Aminodeoxyglycosidase [Glycosaminidase] Glycosiduronase [Glycuronidase] Glyculosidonase [Neuraminidase] [Sialidase]... [Pg.177]

Figure 10.31 Synthetic route to oxygenated pyrrolizidine alkaloids, and an aza-C-disaccharide as glycosidase inhibitors. Figure 10.31 Synthetic route to oxygenated pyrrolizidine alkaloids, and an aza-C-disaccharide as glycosidase inhibitors.
Rye CS, Withers SG (2000) Glycosidase mechanisms, CurrOpin Chem Biol 4 573-580 Saito M, Yu RK (1995) Biochemistry and function of sialidases. In Rosenberg A (ed) Biology of the sialic acids. Plenum, NY, pp 261-313... [Pg.151]

Zechel DL, Withers SG (2001) Dissection of nucleophilic and acid-base catalysis in glycosidases. Curr Opin Chem Biol 5 643-649... [Pg.154]

Triazoline imino sugar derivatives 297 that are prospective glycosidase inhibitors have been prepared as single diastereomers in high yield via an lAOC reaction of in situ generated azido alkene 296 (Eq. 32) [78]. m-CPBA oxidation of the dithioacetal groups in the 0-acetylated 5-azido-5-deoxydibenzyl dithio-acetal of o-xylose or D-ribose 294 to the bis-sulfone 295, followed by loss of HOAc between C-1 and C-2 provided the lAOC precursor 296. [Pg.42]

Fig. 2.—Possible Formation of an Enzyme-linked Acylal (—X = Carboxylate) from an Aldono-1,5-lactone at the Active Site of a / -Glycosidase (after Sinnot and Souchard ). Fig. 2.—Possible Formation of an Enzyme-linked Acylal (—X = Carboxylate) from an Aldono-1,5-lactone at the Active Site of a / -Glycosidase (after Sinnot and Souchard ).

See other pages where Glycosidases 3-Glycosidase is mentioned: [Pg.193]    [Pg.108]    [Pg.226]    [Pg.289]    [Pg.28]    [Pg.1014]    [Pg.270]    [Pg.199]    [Pg.290]    [Pg.295]    [Pg.102]    [Pg.1001]    [Pg.1012]    [Pg.1041]    [Pg.685]    [Pg.590]    [Pg.247]    [Pg.15]    [Pg.56]    [Pg.281]    [Pg.117]    [Pg.147]    [Pg.149]    [Pg.149]    [Pg.38]    [Pg.39]    [Pg.108]    [Pg.207]    [Pg.218]    [Pg.320]    [Pg.320]    [Pg.322]    [Pg.324]    [Pg.324]    [Pg.327]   
See also in sourсe #XX -- [ Pg.87 ]




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A-1,6-Glycosidase

A-Glycosidase inhibitors

A-Glycosidases

A-glycosidase enzyme

Bacterial glycosidases

Calystegines, glycosidase

Carbaaldopyranoses synthesis of glycosidase inhibitors

Carboxylates, active site, glycosidases

Castanospermine glycosidase inhibition

Charania lampas glycosidase

Competitive glycosidase inhibitors

Composition of Glycosidases

Covalent glycosidase inhibitors

Endo-Glycosidases

Endo-glycosidase

Endogenous glycosidase activity

Enol ethers 9-glycosidases

Enzymatic glycosidation glycosidases in synthesis

Enzymes glycosidases

Enzymes glycosidases mechanism

Exo-glycosidases

Exogenous glycosidases

General notes on the practical use of glycosidases

Glycoproteins 3-glycosidase

Glycoproteins glycosidases

Glycosidase

Glycosidase Catalytic Flexibility Catalysis of Substrates with Very Small Aglycon

Glycosidase Reversible Inhibitors

Glycosidase activity

Glycosidase activity of polyphenols

Glycosidase and Glycosyltransferase Structure

Glycosidase enzyme

Glycosidase enzymes, inhibition with

Glycosidase inhibitor

Glycosidase inhibitors alkaloids

Glycosidase inhibitors natural

Glycosidase inhibitors polyhydroxy plant

Glycosidase inhibitors, biologically

Glycosidase inhibitors, glucose

Glycosidase inhibitory activities

Glycosidase inhibitory flavonoids

Glycosidase inhibitory properties

Glycosidase mechanisms

Glycosidase, inverting, mechanism

Glycosidase-Catalysed Oligosaccharide Synthesis

Glycosidase-catalyzed reactions

Glycosidase-catalyzed synthesis

Glycosidases

Glycosidases

Glycosidases Glycosylation reactions

Glycosidases acarbose

Glycosidases activity

Glycosidases carba-sugars

Glycosidases carbohydrates

Glycosidases catalytic flexibility

Glycosidases catalytic mechanism

Glycosidases cellulase

Glycosidases classification

Glycosidases composition

Glycosidases configuration

Glycosidases from different sources

Glycosidases function

Glycosidases glycoconjugate synthesis

Glycosidases glycosynthases

Glycosidases hyaluronidase

Glycosidases iminosugars

Glycosidases inactivation

Glycosidases inhibition

Glycosidases inhibitors

Glycosidases inverting

Glycosidases lysozyme

Glycosidases mechanism-based

Glycosidases mechanisms

Glycosidases mutant

Glycosidases oligosaccharide synthesis

Glycosidases preparation

Glycosidases reactions

Glycosidases retaining

Glycosidases reversible inhibitors

Glycosidases transferase inhibitors

Glycosidases transition-state analogs

Glycosidases yeast

Glycosidases, enzymatic hydrolysis

Glycosidases, modification

Glycosidases, oligosaccharide synthesis with

Glycosidases, specificity

Glycosidases, structure determination

Glycosidases, uses

Glycosyl pyridinium salts P-glycosidases inhibition

Glycosyltransferases and Glycosidases

Grape glycosidases

Hydrolysis by glycosidase

Hydrolysis glycosidases

Hydrolysis retaining glycosidases

Inactivation of Glycosidases - Exo and Paracatalytic Activation

Indolizidine-type glycosidase inhibitor

Indolizidine-type glycosidase inhibitor castanospermine

Indolizidines glycosidase inhibitors

Inhibition glycosidase

Inhibitors of glycosidase activity

Inverting O-glycosidases

Inverting glycosidase

Inverting glycosidases, enzyme

Inverting glycosidases, enzyme kinetics

Isolation glycosidase inhibitor

Kinetics retaining glycosidases

Lysosomal glycosidase deficiencies

Lysosomal glycosidases

Mechanism retaining glycosidase

Microbial glycosidases

N-Glycosidase F (PNGase

O-glycosidases

Oligosaccharide synthesis glycosidases, glycosynthases

Oligosaccharides from glycosidases

Oligosaccharides glycosidases

Oligosaccharides with endo-glycosidases

P-Glycosidase

P-Glycosidases

P-glycosidase inhibitors

Peptide N-glycosidase

Piperidine glycosidase inhibitors

Piperidines glycosidase inhibitors

Plants glycosidase inhibitors

Polyhydroxy plant alkaloids glycosidase inhibitors

Polyhydroxylated glycosidase, inhibitors

Polysaccharides glycosidases

Protecting glycosidases

Pyrrolidines glycosidase inhibitors

Pyrrolizidines glycosidase inhibitors

RNA N-glycosidases

Regioselectivity of glycosidase-catalyzed

Retaining Glycosidase Families

Retaining glycosidases enzyme kinetics

Some Inverting Glycosidase Families

Structural glycosidase inhibitor

Swainsonine glycosidase inhibition

Synthesis using glycosidases

Transfer reactions, catalyzed by glycosidases

Transglycosylation glycosidases

Uracil glycosidase

Uracil-DNA-glycosidases

Winemaking glycosidases

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