Urinary tract stimulation

As gastrointestinal and urinary tract stimulants in postoperative abdominal distention and urinary retention... 

O The lower urinary tract symptoms and signs of benign prostatic hyperplasia are due to static, dynamic, or detrusor factors. The static factor refers to anatomic obstruction of the bladder neck caused by an enlarged prostate gland. The dynamic factor refers to excessive stimulation of a-adrenergic receptors in the smooth muscle of the prostate, urethra, and bladder neck. The detrusor factor refers to irritability of hypertrophied detrusor muscle as a result of long-standing bladder outlet obstruction. 

Echinacea (Echinacea purpurea) Uses immune system stimulant prevention/Rx of colds, flu as supportive th apy for colds chronic infxns of the resp tract lower urinary tract Action Stimulates phagocytosis cytokine production T resp cellular activity topically exerts anesthetic, antimicrobial, anti-inflammatory effects Efficacy Not established may X severity duration of URI Available forms Caps w/ powdered herb equivalent to 300-500 mg, PO, tid pressed juice 6-9 mL, PO, once/d tine 2-4 mL, PO, tid (1 5 dilution) tea 2 tsp (4 g) of powdered herb in 1 cup of boiling water Noles/SE Fever, taste p -version, urticaria, angioedema Contra w/ autoimmune Dz, collagen Dz, progressive systemic Dz (TB, MS, collagen-vascular disorders), HIV, leukemia, may interfere w/ immunosuppressive therapy Interactions t Risk of disulfiram-like reaction W/ disulfiram, metronidazole T risk of exacerbation of HIV or AIDS W/ chinacea amprenavir, other protease inhibitors X effects OF azathioprine, basiliximab, corticosteroids, cyclosporine, daclizumab, econazole vag cream, muromonab-CD3, mycophenolate, prednisone, tacrolimus EMS Possible immunosuppression... 

Although anticholinesterase agents can be used in the treatment of atony of the bladder and adynamic ileus, they are contraindicated in cases of mechanical obstruction of the intestine or urinary tract. Caution should also be used in giving these drugs to a patient with bronchial asthma or other respiratory disorders, since they will further constrict the smooth muscle of the bronchioles and stimulate respiratory secretions. 

Mexico. Decoction of the bark and dried branches is taken orally as an abortive and for diabetes. Decoction of the dried root is taken orally by pregnant humans as an abortive and for diabetes . Infusion of the shade-dried entire plant is taken orally to treat infectious diseases ". Decoction of the dried leaf is taken orally for treatment of diabetes. Hot water extract of the dried leaf is taken orally as a blood purifier to treat kidney problems, urinary tract infections, and frigidity for gallstones, rheumatism and arthritis, diabetes, wounds, and skin injuries, displacement of the womb, and paralysis and to dissolve tumors 5 United States. Hot water extract of the dried leaf is taken orally as a stimulating expectorant and tonic, for tuberculosis, and is drank by Indians of the Southwest for bowel cramps, as a diuretic, and for venereal disease. Hot water extract of the dried leaf is used externally for wound healing . Hot water extract of the dried plant is taken orally for cancer. Effects described are from multicomponent reaction ". 

N.A. Styrax benzoin Dryander Cinnamic, benzoic, sumaresinolic acid esters, benzoic acid, benzaldehyde, vanillin.99 Antiseptic, astringent. Externally for wounds and ulcers, internally to settle cramps, stimulate coughing, disinfect the urinary tract. 

Due to repeat dose toxicity study findings being restricted to high dose levels with reversibility demonstrated, it is concluded that HP-P-CD is a well tolerated excipient. For carcinogenicity study, urinary tract changes were reported as due to osmotic necrosis, intestinal tumours were related to increased osmotic activity and pancreatic tumours were shown to be due to rat-specific hormonal stimulation... 

Methylchromone (Tricromyl or Crodimyl) possesses muscle relaxant properties and exerts a vasodilator effect on coronary blood vessels, whilst the flavone derivative Flavoxate (Urispas) (725) is an antispasmodic agent which reduces smooth muscle spasm in the urinary tract. The isofiavone Formononetin (726) is a diuretic and Dimeffine (Remeflin) (727) is a respiratory stimulant. 

Benefits A bitter aromatic herb with a fig/date-like flavour that is claimed to be a nerve stimulant and was used to treat nervous exhaustion and anxiety of a sexual nature. It is claimed to be a mild irritant of the genito-urinary tract. 

The diuretic property of celery has been used to prepare herbal medicine (Houghton, 1995). The ripe seeds, herb and root are diuretic (Lust, 1983 Chiej, 1984 Grieve, 1984). The seeds are used mainly as a diuretic and can help clear toxins from the system, especially in cases of gout where uric acid crystals collect in the joints. Root tinctures have been used to cure urinary disorders, such as urinary stones, and used as a kidney stimulant and cleanser. Fresh juice from the whole plant is also used as a cure for urinary tract inflammations and urethritis (http //www.innvista.com/health/herbs/ celery.htm). The herb is used against kidney complaints (Launert, 1981). 

Is commonly known as Spanish fly and is derived from blister beetles. Karras speculates that it may be a more common cause of morbidify than is recognized [12]. It is used as a sexual stimulant and is an ingredient in some wart removal remedies [13]. Poisoning is noteworthy for its dramatic effect on the gastrointestinal and urinary tracts, as well as occasionally inducing cardiac abnormalities and seizures [12,13]. The patient... 

Intravesical BCG promotes an inflammatory reaction ir the urinary bladder that is a.ssociatcd with reduction incatii-noma in situ lesions. The mechanism of action is not knosa in detail, but a variety of processus that stimulate the imnwnr response have been considered. Toxic effects of BCG in elude hematuria, dy.suria. and bacterial urinary tract infections. 

There is widespread use of Crinum species throughout the African Continent for the treatment of a variety of ailments. In southern Africa, Crinum bulbispermum is used by the Zulu and Tswana for the treatment of aching joints, rheumatism, varicose veins, backache, septic sores and abscesses. Tswana also use the bulb to treat kidney or bladder infections while in Sotho cultures the bulb is used for stimulation of milk production (44, 43). Bulb decoctions of Crinum maco-wanii are taken for the treatment of swelling of the body and treatment of urinary tract problems by the Zulu and for itchy rashes by the Xhosa (43, 44,... 

In Zimbabwe, bulbs are used as emetics and to stimulate milk production in both women and cows. The Zulu also use bulb decoctions of Crinum moorei and C. delagoense for swelling of the body and for urinary tract problems (43,... 

Acute toxicity includes pupillary constriction, stimulation of GI tract (cramps, nausea, vomiting, and diarrhea [NVD]) and urinary tract (incontinence, urination), bronchoconstriction (wheezing, dyspnea), increased glandular secretions (sweating, salivation, lacrimation), bradycardia and hypotension, skeletal muscle fasciculations and then paralysis (e.g., respiratory muscles), and CNS effects (behavioral excitation, depression of cardiovascular [CV] and respiratory centers). 

Bethanechol incorporates the stabilizing structural features of both methacholine and carbachol. Thus it is like carbachol in that no appreciable cholinesterase hydrolysis takes place, and like methacholine it does not stimulate ganglia or skeletal muscle. This dmg appears to show some specificity of action in the gastrointestinal and urinary tracts. Thus, it has clinical applications in postoperative distention of the abdomen and bladder in the latter case it relieves the urinary retention that results following surgery. The drug is even orally effective. 

GASTROINTESTINAL AND URINARY TRACTS Although stimulation of vagal input to the gastrointestinal (GI) tract increases tone, amplitude of contraction, and secretory activity of the stomach and intestine, such responses are inconsistently seen with administered ACh. Poor perfusion of visceral organs and rapid hydrolysis by plasma butyrylcholinesterase limit access of systemically administered ACh to visceral muscarinic receptors. Parasympathetic sacral innervation causes detrusor muscle contraction, increased voiding pressure, and ureter peristalsis, but for similar reasons these responses are not evident with administered ACh. 

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