Crinum moorei

Fig. 2 shows a typical separation of 3 g of three alkaloids from a crude extract of Crinum moorei using a binary... 

Fig. 2 Chromatograms of the crude alkaloid extract of Crinum moorei obtained by pH-zone-refining CCC. Experimental conditions were as follows apparatus high-speed CCC centrifuge equipped with a multiplayer coil of 1.6 mm LD. and about 300 mL capacity solvent system methyl-ferf-butyl ether-water stationary phase (A) upper phase (5 mM triethylamine) and (B) lower phase (10 mM HCl) mobile phase (A) lower phase (5 mM HCl) and (B) upper phase (10 mM triethylamine) flow rate 3.3 mL/min sample crude alkaloid extract of C. moorei, 3 g dissolved in 30 mL of each phase revolution (A) 800 rpm (600 rpm until 66 mL of mobile phase was eluted) and (B) 600 rpm throughout.

In Zimbabwe, bulbs are used as emetics and to stimulate milk production in both women and cows. The Zulu also use bulb decoctions of Crinum moorei and C. delagoense for swelling of the body and for urinary tract problems (43,... 

Lectin-like proteins from Crinum moorei aggregated Staphyllococus aureus at 19 ag/ml and inhibited bacterial growth at a concentration of 0.8 mg/ml. No snch effects were observed against Bacillus subtilis (96). 

Also, a zone refining partition coefficient technique has been developed to separate the alkaloids present in a crude extract of Crinum moorei (32). 

Acetyllycorine was isolated from the seeds of Crinum moorei by Crowder and Wildman (74). The alkaloid, m.p. 220-221°, gave diacetyl-lycorine on acetylation and lycorine when reduced with lithium aluminum hydride. It is identical with the 1-aoetyllyoorine prepared by the acid hydrolysis of diacetyllycorine according to the method of Nakagawa et al. (103). 

The identity and structure of crinamidine itself is still the subject of controversy. The alkaloid is reasonably common in Buphane, Crinum, Habranthus, Hippeastrum, and Nerine species (11,14, 18, 20, 21, 30-32, 48). The first isolation of the alkaloid from Crinum moorei describes it as a levorotatory base (122). In the experimental section of the same paper the specific rotation was given as +24°. The alkaloid was assigned the structure CXL because it gave a positive test for a vicinal glycol and the IR-spectrum was very similar to that of powelline (123). 

Crinine C,6H,7N03 271.32 207-208 +26° (CHCI3) Hippeastrum vittatum Crinum moorei 510-67-8... 

Elgorashi EE, Drewes SE, van Staden J (2001) Alkaloids from Crinum moorei. Phytochemistry 56 637... 

Fennell CW, Elograshi EE, van Staden J (2003) Alkaloid production in Crinum moorei cultures. J Nat Prod 66 1524... 

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