Diuretic properties

Atrial Natriuretic Factor. Atrial natriuretic factor (ANF) has natriuretic, vasorelaxant, and diuretic properties (142). It was originally discovered in atrial tissue, from which extracts were made and subsequendy injected systematically. The responses evoked from the atrial extracts estabhshed the heart as an endocrine organ. 

It has been documented in an earlier volume that appropriately substituted molecules with two strongly electron withdrawing substituents meta to one another in a benzene ring often possess diuretic properties and, even though the prototypes usually have two substituted sulfonamide moieties so disposed, other groups can replace at least one of them. An example of this is piretanide (24), where one such group is a carboxyl... 

Many benzenesulfonamides have diuretic properties, particularly those having two such functions situated meta to one another. To some extent a carboxyl group can serve in place of one of the sulfonamido groups. Bumetanide (8) is such a substance. Chlorosulfonation of p-chlorobenzoic acid leads to 5, which is nitrated, and then converted to sulfonamide 6 with ammonia. 

The diuretic properties of ethacrynic acid (95) were at one time attributed to its role as a Michael... 

Theophylline, a dimethylxanthine, causes broncho-dilation, possibly by inhibiting the enzyme phosphodiesterase in smooth muscle of the bronchioli. An other proposed mechanism of action is that of adenosine receptor antagonism. It has positive chronotropic and inotropic, CNS stimulant and weak diuretic properties. In obstructive lung disease sustained release tablets are to be preferred. Theophy-line has a narrow therapeutic index. Therapeutic plasma concentrations are between 7-15 mg/1. Theophylline undergoes N-demethylation via CYPl A2 in the liver and is eliminated in the urine as metabolites... 

N.A. Tannins, flavonoids, polyphenols, silicic acid, mucilage.99102 With astringent and diuretic properties. Treat diarrhea, hemorrhoids, expel worms. 

N.A. Akebia trifoliata (Thunb.) G. Koidz. No information is available in the literature. Control infection, stimulate the circulatory and urinary systems. Diuretic properties.345... 

N.A. Euonymus atropurpureus Jacq. Cardienolides, cardiac glycosides, asparagine, sterols, tannins.99 A gallbaldder remedy with laxative and diuretic properties. Treat biliousness, liver problems, eczema, constipation. 

Beer, from grain, especially barley, he considers as especially deleterious, as it bloats, promotes obesity, attacks the kidneys through its diuretic properties, and irritates the nervous system and the brain. 

Theobromine is an alkaloid found in the cocoa shell, tea (only in very small amounts), and kola nuts, but it is not found in coffee. In cocoa, its concentration is generally about seven times as great as CF. Although CF is relatively scarce in cocoa, it is mainly because of TB that cocoa is stimulating. TB is considerably weaker than CF and TP, having about one-tenth the stimulating effect of either. Its diuretic properties are well known (253), however, and it is also used in other applications in the pharmaceutical field. 

Benefits Significant antirheumatic and antiaithritic actions have been demonstrated in several studies, some with large groups of participants. Diuretic properties have been reported in connection with prostate problems and in cases of lower urinary tract infections. 

Agrimony is believed to possess mild astringent and diuretic properties. It is used to treat diarrhea in children, mucous colitis, grumbling appendicitis, urinary incontinence, cystitis, and as a gargle for acute sore throat and chronic nasopharyngeal catarrh. 

Buchu is believed to possess urinary antiseptic and diuretic properties. It has been used for cystitis urethritis, prostatitis, and specifically to treat acute catarrhal cystitis. 

Devil s claw is reputed to possess anti-inflammatory, antirheumatic, analgesic, sedative, and diuretic properties. It is used to treat arthritis, gout, myalgia, fibrositis, lumbago, pleurodynia, and especially rheumatic disease. 

Squill possesses expectorant, cathartic, emetic, cardioactive, and diuretic properties. Traditionally, it has been used for chronic bronchitis, asthma with bronchitis, whooping cough, and specifically for chronic bronchitis with scanty sputum. 

Used as a digestive. Its stimulant and diuretic properties are said to be of value in the treatment of dropsy, but it is rarely prescribed by modern herbalists. 

The structures of various substituted 3-aryl-anhydro-5-amino-l,2,3,4-oxatriazoline hydroxides 6 (R1 =Ar) for the treatment of asthma and thrombosis have been disclosed <1996W096/11191> and their diuretic properties have also been alluded to <2006W02006/055542>. 

Many Erythrina alkaloids possess curare-like action. Alkaloidal extracts from different parts of Erythrina species have been used in indigenous medicine, particularly in India (176). Many pharmacological effects, including astringent, sedative, hypotensive, neuromuscular blocking, CNS depressant, laxative, and diuretic properties, have been recorded for total alkaloid extracts, although not all these properties can be associated with the ery-thrinane structure alone (38, 177, 178). 

Dithiole-3-thione, methylation of, 391 Di-(trimethyisilyl) amine, reaction with A-4-thiazoline-2-thione, 396 Diuretic sulfonamide, 414 Diuretic properties, 150, 152 Dithiobiuret, 85... 

The ANF hormones, which derive from higher-molecular-weigth precursors (atriopeptigens), have diuretic properties, i.e. an administration of ANF in the rat increases diuresis and natriuresis (the release of Arg-vasopressin is inhibited) and at the same time the vessels are dilated, apparently by inhibition of catecholamines and angiotensin II. In addition, it has been shown that under volume loading the ANF peptides are released from the atria and develop their effects as hormones in renal, vascular, and other tissues. They can be considered as functional antagonists of the renin-angiotensin system. 

Tamarind preparations are recognized universally as refrigerants in fevers and as laxatives and carminatives (Morton, 1987). The laxative properties of the pulp and the diuretic properties of the leaf sap have been confirmed by modern medicinal science (Bueso, 1980). In South-east Asia,... 

The diuretic property of celery has been used to prepare herbal medicine (Houghton, 1995). The ripe seeds, herb and root are diuretic (Lust, 1983 Chiej, 1984 Grieve, 1984). The seeds are used mainly as a diuretic and can help clear toxins from the system, especially in cases of gout where uric acid crystals collect in the joints. Root tinctures have been used to cure urinary disorders, such as urinary stones, and used as a kidney stimulant and cleanser. Fresh juice from the whole plant is also used as a cure for urinary tract inflammations and urethritis (http //www.innvista.com/health/herbs/ celery.htm). The herb is used against kidney complaints (Launert, 1981). 

Celery is used both as a vegetable and a spice. It has several medicinal uses. It is believed to cure most urinary disorders. It has diuretic properties. It is also commonly used to relieve pain. Limonene is the major volatile compound in both leaf and seed oil. Phthalides, myrcene, pinene, etc., are also present. Higher nitrogen inhibited limonene... 

Aloe 2. Dandelion 3. Elder 4. Liquorice 5. Nettle 6. Rhubarb 1. Bendroflumethiazide 2. Bumetanide 3. Chlortalidone 4. Hydrochlorothiazide 5. Indapamide 6. Furosemide 7. Torasemide Low body potassium, which may give rise to lethargy and muscle weakness t potassium loss from the gut (aloe, liquorice) Possess diuretic properties (dandelion, elder, nettle, rhubarb) Avoid concomitant use. Provide potassium supplements orally. Use a potassium-sparing diuretic such as spironolactone or amiloride... 

The corresponding 8-methyl derivative, tcctochrysin 488, having diuretic properties, is synthesized by hydrogenolysis of the aminomethylated intermediate. ... 

PUFAs suppress HMG-CoA reductase and ACE activities, inhibit platelet aggregation, enhance parasympathetic activity and, thus, enhance heart rate variabihty (and thus, have actions similar to that of fS-blockers), and possess diuretic properties either by themselves and/or by increasing the formation of PGAs and PGEs that have been shown to increase renal blood flow and augment diuresis. These actions of PUFAs are similar to that of the polypill that is a combination of aspirin, fS-blockers, statins, and ACE inhibitors, which is expected to reduce cardiovascular diseases by over 70-80% (92). This suggests that PUFAs could function as an endogenous polypill the evidence for this is detailed below. 

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